PedAM
Pediatric Disease Annotations & Medicines
| Disease | tuberculosis |
| Symptom | C0009450|infection |
| Sentences | 645 |
| PubMedID- 26493989 | During the early stages of infection with tuberculosis there is a high t helper (th) 1, and to some extent th17, immune response to m.tb antigens . |
| PubMedID- 22927933 | infection with mycobacterium tuberculosis (mtb) kills about 2 million people each year and goes hand-in-hand with hiv-1. |
| PubMedID- 21674801 | Evidence of infection with mycobacterium tuberculosis, the causative agent of tb, has been dated to the neolithic period (7000 bc) and has been observed in egyptian mummies (2050–500 bc) 1, 2. reference is made to tb in literature from both ancient china and india dating to 4000–2000 bc as well as in biblical scripture 3. historically known as consumption in the west, tb was a common disease that led to the death of many historic figures (e.g. |
| PubMedID- 23355991 | From 2007 to 2010, 229 newly notified tuberculosis (tb) cases with hiv infection were reported. |
| PubMedID- 26319069 | Mycobacterium tuberculosis (m.tb) infection leads to active tuberculosis (tb), a disease that kills one human every 18s. |
| PubMedID- 24209898 | Dual infection with m. tuberculosis and b. pseudomallei has been reported previously including a case presenting with a neck abscess . |
| PubMedID- 22679504 | Active tuberculosis disease (tb) resulting from infection with beijing strains has frequently been associated with tb outbreaks , antituberculosis drug resistance , , , treatment failure and relapse –. |
| PubMedID- 25407624 | Background: infection of livestock with bovine tuberculosis (btb; mycobacterium bovis) is of major economical concern in many countries; approximately 15 000 to 20 000 cattle are infected per year in ireland. |
| PubMedID- 22675328 | Follow-up studies comparing the h. pylori infection status of active tuberculosis cases and non-progressing household contacts revealed a significantly higher h. pylori seroprevalence in the latter group. |
| PubMedID- 25252198 | The heparin-binding haemagglutinin (hbha) appears to be a promising vaccine candidate, as it was shown to afford protection to mice against a challenge infection with mycobacterium tuberculosis when combined with the strong adjuvant dda/mpl (dimethyldioctadecyl-ammonium bromide/monophosphoryl lipid a), a tlr4 ligand. |
| PubMedID- 26091535 | Visible cell aggregation occurred on day 3 post-infection with m. tuberculosis (fig 3a, b). |
| PubMedID- 23853585 | Mice deficient in the expression of socs3 either in myeloid or lymphoid cells were extremely susceptible to infection with m. tuberculosis as measured by elevated bacterial levels, worsened pathology and reduced survival. |
| PubMedID- 23110184 | Co-infection with m. tuberculosis and pbnk65 therefore is a highly relevant model to study the effects of malaria-induced pulmonary pathology on the outcome of tuberculosis. |
| PubMedID- 20096113 | After infection with m. tuberculosis, the site of disease is likely determined by interactions between the pathogen and the host immune response. |
| PubMedID- 24818083 | Background: urine tests for mycobacterial lipoarabinomannan might be useful for point-of-care diagnosis of tuberculosis in adults with advanced hiv infection, but have not been assessed in children. |
| PubMedID- 22363768 | The other 9 mice in each group were retained for the infection experiment with m. tuberculosis virulent strain h37rv. |
| PubMedID- 22265677 | These animals also succumb rapidly to aerosol lung infection with mycobacterium tuberculosis (dorhoi et al., 2010). |
| PubMedID- 26495323 | Based on careful surveys of the literature and published works from our group, we have come to the following conclusions:the balance between resistance and susceptibility to infection with m. tuberculosis is a very complex mechanism and presents several controversies over the cytokine profiles of t helper cell subpopulations.il-10 appears to have an important role in shaping the repertoire of t helper lymphocytes, irrespective of other cytokines that define their subpopulations.chronic infection in the presence of il-10 appears to exert a regulatory role and minimize tissue damage, but without compromising the immune mechanisms involved in the control of m. tuberculosis and other related microorganisms. |
| PubMedID- 24819223 | We assessed bacterial community composition and diversity prior to infection with m. tuberculosis cdc1551 and throughout infection until death. |
| PubMedID- 23671394 | Childhood outcome parameters reviewed were: (1) the onset of physician diagnosed asthma; (2) lower respiratory tract infection (lrti) with wheezing, latent tuberculosis infection/wheezing diagnosed on physical examination; (3) nonsurgical hospitalization; (4) atopic disease (eye/skin/nasal-sinus disease); (5) infections: ear, lrti, sinus. |
| PubMedID- 22894713 | In cameroon for instance, the prevalence of hiv infection among those with smear-positive pulmonary tuberculosis increased from 16.6% in 1997 to about 29.3% in 2007 . |
| PubMedID- 25114132 | In sub-saharan africa, mdr/xdr tuberculosis with hiv coinfection is common, and concurrent treatment of hiv infection and mdr/xdr tuberculosis is required. |
| PubMedID- 22509293 | We have reported the down regulation of ifngr1 following infection with m. tuberculosis, . |
| PubMedID- 22078446 | Aim: to study the production of nitric oxide and secretion of cytokines after infection of macrophages with mycobacterium tuberculosis h37ra. |
| PubMedID- 21345183 | In the majority of humans, an effective immune response develops after infection with m. tuberculosis and restricts the spread of the pathogen and clinical manifestation of the disease is seen in less than 10% of those infected. |
| PubMedID- 20824975 | Some inmates were already exposed to infection due to m. tuberculosis outside before imprisonment given that four (36.4%) of the 11 inmates who had spent only ≤3 months in the prison at the time of screening, including the new inmate who had spent only two days, were tst-positive. |
| PubMedID- 26091717 | Stimuli used were direct infection with m. tuberculosis strain h37rv or conditioned medium from m. tuberculosis–infected monocytes (comtb). |
| PubMedID- 25819058 | Phylogenetic works examining the available materials (dnaa) suggest that mycobacterium tuberculosis, the cause of tuberculosis infection in humans and cattle (aurochs), would have had a co-evolutionary process. |
| PubMedID- 26175777 | The diagnosis of ptb was considered to be definitive if (1) microbiological testing (acid-fast bacillus staining, polymerase chain reaction, or culture) using lower respiratory tract specimens confirmed infection with mycobacterium tuberculosis or (2) the patient's clinical presentation met the criteria for clinical active ptb established by the world health organization2021. |
| PubMedID- 24778828 | The authors suggested that infection with m. tuberculosis during childhood might alter immunogenic responses that may act to reduce the incidence of atopic diseases. |
| PubMedID- 24722524 | This is exemplified by the potent pro-inflammatory cytokine and acute phase responses that follow infection with m. tuberculosis, and their reduction upon antibiotic treatment . |
| PubMedID- 24133190 | After infection of cells with mycobacterium tuberculosis, bacterial burden was determined. |
| PubMedID- 20659314 | Ltbi was defined as infection with m. tuberculosis, without any clinical manifestation, and was diagnosed if tst ≥ 10 mm or igra > 0.35 iu/ml after exclusion of active tb regardless of cxr results due to the low sensitivity and specificity of cxr for the diagnosis of ltbi. |
| PubMedID- 22084651 | This is the first case of combined infection with tuberculosis and mucormycosis reported in such a host, with a favourable outcome. |
| PubMedID- 23474302 | Recently, it was shown that interferon-gamma mediated immune responses, which play a major role in the control of infection with mycobacterium tuberculosis (mtb), can be inhibited by type i interferons. |
| PubMedID- 24568242 | Hiv increases the risk of rapid tb progression after primary infection or re-infection with mycobacterium tuberculosis (mtb) and increases the risk of reactivating latent tb infection . |
| PubMedID- 26032055 | On logistic regression sex, tobacco use, perceived health status and facing discrimination due infection with tuberculosis were found to be factors associated with alcohol use. |
| PubMedID- 26258152 | infection with mycobacterium tuberculosis (mtb), the causative agent of tuberculosis (tb), was responsible for 1.5 million deaths and 9 million cases of tb in 2013, according to the world health organization 1. |
| PubMedID- 21483732 | However, the risk of infection with m. tuberculosis and progression to tuberculosis disease is influenced by host factors and especially risk of progression depends on the hosts' immune status, which may be reduced due to concomitant hiv infection, diabetes, and other underlying diseases , . |
| PubMedID- 20950462 | Similar uptake was observed at different multiplicities of infection with m. tuberculosis (p > 0.05 for each moi). |
| PubMedID- 20735862 | Furthermore, not all instances of mycobacterial infection may be due to m. tuberculosis, as mycobacterium avium and others also account for reactivated disease . |
| PubMedID- 25691598 | The host-pathogen interplay during infection with m. tuberculosis is incredibly complex and, despite accelerating progress in research, remains poorly understood, particularly with regard to the human processes involved. |
| PubMedID- 26187708 | Screening for the presence of latent infection with mycobacterium tuberculosis and targeted preventive treatment to reduce the risk of progression to tb is mandatory in these patients. |
| PubMedID- 24255121 | To assess the role of cor in vivo, we compared the outcomes of mouse infection with wild-type m. tuberculosis, the cor mutant, and the complemented strain. |
| PubMedID- 26318132 | On the other hands, the caseation necrosis and multinucleated giant cells were observed on an excised cervical lymph node, suggesting infection with the m. tuberculosis (fig. |
| PubMedID- 21203587 | infection with m. tuberculosis can be diagnosed using the tuberculin skin test; tests for tb itself include chest x-rays and sputum cultures (in which bacteriologists try to grow m. tuberculosis from sputum samples, mucus brought up from the lungs by coughing). |
| PubMedID- 23230324 | indicated that helminth infection coincident with m. tuberculosis significantly diminishes m. tuberculosis-specific th1 (il-12/ifn-γ) and th17 (il-23/il-17) responses in latent tuberculosis. |
| PubMedID- 20174568 | During the mouse infection with m. tuberculosis h37ra, we implanted wild type mice and tlr9 knockout mice with a 25 mg sustained-release morphine pellet, while control mice received a comparable placebo pellet for different time periods and determined apoptotic cells using the tunel technique. |
| PubMedID- 24336213 | tuberculosis initiates infection in the relatively sterile environment of the lower respiratory tract, rather than in the upper respiratory tract, where resident microflora and inhaled environmental microbes may continually recruit microbicidal macrophages through tlr-dependent signalling. |
| PubMedID- 19926735 | However, these tests cannot discriminate between recently acquired infection (higher risk of progression to active tuberculosis) and remote ltbi. |