PedAM
Pediatric Disease Annotations & Medicines
| Disease | tuberculosis |
| Symptom | |infection |
| Sentences | 645 |
| PubMedID- 22912845 | infection with tuberculosis (tb) remains the leading cause of mortality among hiv-infected people worldwide 1. |
| PubMedID- 23383015 | tuberculosis is strongly associated with hiv infection, but melioidosis is not. |
| PubMedID- 21931620 | On days 2 and 4, the cells were fed by changing 75% of the media and non-adherent cells were harvested on day 6. prior to infection with m. tuberculosis, cells were seeded into 48-well plates at 2×105 cells/well. |
| PubMedID- 24205032 | The guinea pig model of low dose aerogenic infection with virulent m.tuberculosis has been preferentially used to elucidate the events in the pathogenesis of pulmonary tuberculosis . |
| PubMedID- 26039731 | Many animal studies have shown that both type 1 diabetes mellitus (t1dm) and t2dm lead to increased susceptibility to infection with mycobacterium tuberculosis (mtb), which is responsible for human tuberculosis (tb) . |
| PubMedID- 23824716 | The role of cell-mediated immunity in infection with m. tuberculosis has been reinforced over the last years either in experimental models or in studies of the human disease. |
| PubMedID- 26260753 | Incidence and clinical outcomes of clostridium difficile infection after treatment with tuberculosis medication. |
| PubMedID- 26064938 | Discrepancies in drug susceptibility test for tuberculosis patients resulted from the mixed infection and the testing system. |
| PubMedID- 22851964 | demonstrated that infection with virulent m. tuberculosis or the addition of manlam upregulates pparγ expression independent of nf-κb in human macrophages. |
| PubMedID- 25704441 | Risk of infection and disease with mycobacterium tuberculosis among children identified through prospective community-based contact screening in indonesia. |
| PubMedID- 26459522 | We conclude with the recommendation that clinicians in high tb-hiv burden settings strongly consider empiric anti-tuberculosis treatment in patients with advanced hiv infection and severe sepsis in the appropriate clinical context. |
| PubMedID- 25422024 | Although diagnosis and treatment of infection with mycobacterium tuberculosis (also referred to as latent tuberculosis infection ltbi or tb infection) remain the lynchpins of tb prevention, there is no diagnostic reference standard for ltbi. |
| PubMedID- 23110093 | We screened the remaining articles in order to only select those reporting actual infection of mice with m. tuberculosis, hence excluding studies on humans or other animal models, or in vitro studies and infections with other mycobacteria (figure 1). |
| PubMedID- 25703560 | Il-1β is massively induced upon infection of macrophages with m. tuberculosis, and it appears to play important roles in anti-mycobacterial immune defenses because knockout mice are more susceptible to this infection (98), and human polymorphisms of il-1 genes were associated with susceptibility to tuberculosis (99). |
| PubMedID- 23853593 | Every 3–4 days into μmt mice, starting 1 day before infection with 100–300 cfu of m. tuberculosis erdman, and continued for 1 month thereafter. |
| PubMedID- 24376899 | infection with m. tuberculosis increased the processing of lc3 in dc2.4, whereas there was no significant increase in lc3 processing upon bcg infection. |
| PubMedID- 22174569 | In addition, the infection increases the risk of latent tuberculosis reactivation, a new infection progression or re-infection to active disease, increasing the risk of the emergence of hiv resistant strains to the usual antiretroviral therapy. |
| PubMedID- 25215126 | 6 another important point to keep in mind is the association of tuberculosis with hiv infection, and such patients must always be screened for hiv if the diagnosis of tuberculosis is made. |
| PubMedID- 22084539 | Although the prevalence of hiv infection among patients with tuberculosis ranges from 50% to 80% in many settings in sub- saharan africa, in other parts of the world it varies from 2% to 15%. |
| PubMedID- 21258569 | Mycobacterium avium complex (mac) lung disease in two inner city community hospitals: recognition, prevalence, co-infection with mycobacterium tuberculosis (mtb) and pulmonary function (pf) improvements after treatment. |
| PubMedID- 24624130 | During the course of infection with mycobacterium tuberculosis, it has been observed that poly ic:lc treatment twice daily after infection enhances bacterial replication and induces extensive areas of necrosis in the lungs of treated mice compared to untreated mice (59). |
| PubMedID- 23971009 | Pges−/− macrophages are unable to control h37rv replication and pges−/− mice demonstrate significantly higher bacterial burdens at 5 weeks post-infection with virulent m. tuberculosis, suggesting that pge2 is necessary to control m. tuberculosis during the early stage of infection (chen et al., 2008). |
| PubMedID- 23540085 | Background: co-infection with tuberculosis adversely affects the quality of life of hiv infected individuals and additionally, hiv testing among tb patients gives an opportunity for prevention and treatment of hiv infection. |
| PubMedID- 25999670 | We have previously reported the generation of rgptnf-α using a prokaryotic expression system and have used this reagent to study the contributions of tnf-α to the response of both phagocytic cells and whole animals to infection with virulent m. tuberculosis . |
| PubMedID- 21629653 | Plcg2 was reported to be activated after infection with attenuated m. tuberculosis strains regulating several functions of neutrophils such as generation of reactive oxygen intermediates (roi) and induction of mapk-signalling . |
| PubMedID- 22844400 | Furthermore, we observed elevated levels of ido gene expression and enzymatic activity in human dcs and macrophages upon infection with m. tuberculosis (figure 5b–e). |
| PubMedID- 20126383 | The most frequent diagnosis among hiv-infected participants was infection with tuberculosis, pneumonia, cryptococcosis, and blood stream infections being the most frequent diagnoses. |
| PubMedID- 21483832 | Background: macrophage cell death following infection with mycobacterium tuberculosis plays a central role in tuberculosis disease pathogenesis. |
| PubMedID- 21556333 | However, knockout-mice lacking ccl2 were not found to be more susceptible to intravenous infection with m. tuberculosis and published studies on the ccl2 variation from different world regions produced somewhat controversial conclusions , . |
| PubMedID- 24666844 | There is widespread infection with bovine tuberculosis in ethiopian cattle . |
| PubMedID- 25918263 | Because the pulmonary malt lymphoma developed in a background of tubercular sequelae, and there was no nodal involvement to suggest disseminated disease, we believe that the pulmonary malt lymphoma is likely to have developed de novo and that chronic inflammation due to past infection with m. tuberculosis may have contributed to the development of lymphoma. |
| PubMedID- 20494110 | Despite differences in the immunopathogenesis of human infection with tuberculosis and hiv, experimental evidence from clinical studies and relevant animal models can be used to reflect on the cellular mechanisms responsible for an increased risk of active tuberculosis among hiv-infected individuals. |
| PubMedID- 21943115 | In multivariable analysis adjusted for age, sex, body mass index, cd4 count and co-infection with tuberculosis, being on art was significantly and positively associated with raised total cholesterol, ldl-cholesterol and tc/hdl cholesterol. |
| PubMedID- 21829471 | Pleural tuberculosis (pltb) results from m.tuberculosis infection of the pleura and can be associated with pulmonary tuberculosis 2. |
| PubMedID- 24498059 | In a study among prisoners in cameroon 4, hiv infection was associated with prevalent tuberculosis (including those on treatment) but not with undiagnosed prevalent tuberculosis. |
| PubMedID- 22174691 | Moreover, mitochondrial damage has been suggested to play a critical role in the outcome of macrophage infection with m. tuberculosis . |
| PubMedID- 22738332 | Systemic infection with mycobacterium tuberculosis (bacillus calmette-guérin, bcg) leads to acute changes in locomotor activity, followed by depressive symptoms at 7 days that coincide with an increase in indoleamine 2,3-dioxygenase (ido) and increased mrna levels of ifn-γ, il-1β and tnf-α in the brain . |
| PubMedID- 20661284 | A hallmark of infection with mycobacterium tuberculosis (mtb) is the organism's ability to survive for months to decades in an asymptomatic state, before reactivating in a subset of infected individuals to cause frank disease. |
| PubMedID- 23676155 | Objectives: to estimate the prevalence of infection with mycobacterium tuberculosis and the annual risk of tuberculous infection (arti) and to compare this with the prevalence of tuberculosis (tb) over study clusters and households. |
| PubMedID- 25878511 | Coinfection with hiv and tuberculosis is an extremely common problem, and, in areas of high prevalence, it is the most common coinfection in hiv-positive children.35 hiv and tuberculosis pathogens interact, resulting in weight loss, which is the presenting feature in almost 50% of cases of tuberculosis, and persistent anorexia, a feature in approximately one-quarter of cases, also contributes to undernutrition.38 furthermore, malnutrition is a risk factor for the acquisition of primary tuberculosis infection, as well as progression to active disease. |
| PubMedID- 22243650 | infection of hbmec with m. tuberculosis for invasion and intracellular survival assays was performed in triplicate at a multiplicity of infection (moi) of 10:1 as described previously . |
| PubMedID- 22692456 | For example, leptin signaling during infection with m. tuberculosis was important for regulation of the immune response and bacterial containment 15. in contrast, wilson et al, recently found il-22 to be dispensable for an appropriate immune response to numerous pathogens including m. tuberculosis 86. furthermore, ob/ob mice lacking leptin are protected against dss colitis, while il-22-/- mice showed more severe pathology 42, 87. thus, the circumstances in which these cytokines act is critical and allow for a fine-tuned and seamless immune response. |
| PubMedID- 23231044 | infection with mycobacterium tuberculosis is accompanied by an intense inflammatory response. |
| PubMedID- 24341851 | Also, it has been demonstrated recently that infection with intracellular mycobacterium tuberculosis activates the alternative phenotype of macrophages that inhibit autophagy-dependent maturation and killing of mycobacteria, which indicates that alternative activation of macrophages may contribute to the persistence of mycobacterial infection . |
| PubMedID- 20505769 | Prevalence of hiv infection among patients with tuberculosis in mainland china (part 1/2). |
| PubMedID- 22139204 | infection with mycobacterium tuberculosis causes primarily formation of granulomatous tubercles in the lungs. |
| PubMedID- 25658731 | Co-infection with mycobacterium tuberculosis (mtb) and human immunodeficiency virus (hiv) represents a major threat to public health worldwide. |
| PubMedID- 23287606 | Quantiferon-tb gold assay (qft-g) is more specific for infection with mycobacterium tuberculosis than the tst, especially among persons vaccinated with bacillus calmette-guerin, thereby reducing the number of false positive tests. |
| PubMedID- 22529866 | In addition, arginase-1 knockouts exhibit enhanced no production in bcg-infected macrophages and lower bacterial burdens in an aerosol infection model of m. tuberculosis . |
| PubMedID- 24741201 | The present case report is about a 56-year-old woman was diagnosed to have hiv 1 infection with pulmonary tuberculosis in 2002. viral load was 127,717 copies/ml with a cd4 cell count of 221 cells/μl. |