PedAM
Pediatric Disease Annotations & Medicines
| Disease | tuberculosis |
| Symptom | |infection |
| Sentences | 645 |
| PubMedID- 22546938 | In humans and non-human primates, infection with m. tuberculosis induces formation of a heterogeneous and dynamic range of highly structured granulomatous lesions that provide a multiplicity of bacterial microenvironments.1 successful pathogenesis involves an ability to tolerate the resulting unfavorable environments, and to exploit environments that are favorable for bacterial multiplication, access to airways and onward transmission. |
| PubMedID- 22247303 | In zambia, autopsy studies of hiv-positive children who died from respiratory disease identified hcmv as a frequent infection, often together with tuberculosis . |
| PubMedID- 25838829 | Seven people (4.5%) had infection with inh-r m. tuberculosis, none of whom recalled having previously received tb treatment. |
| PubMedID- 22614321 | Purpose: tuberculous optic neuropathy may follow infection with mycobacterium tuberculosis or administration of the bacille calmette-guerin. |
| PubMedID- 25248372 | Screening travellers to high-endemic countries for infection with mycobacterium tuberculosis using interferon gamma release assay; a prospective study. |
| PubMedID- 21208468 | Mortality from 2009 h1n1 is not common but data from south africa, where the incidence of co-infection with hiv and tuberculosis is high, reveal that 65% of fatal cases were females of reproductive age, of whom almost half were pregnant . |
| PubMedID- 21745408 | This report highlights the need to control the infection in wildlife reservoirs of bovine tuberculosis and the importance of research on the interaction between infected wild boars and bovine tuberculosis in cattle. |
| PubMedID- 22003199 | Il-23 is required for the il-17 response to infection with mycobacterium tuberculosis, but is not required for the early control of bacterial growth. |
| PubMedID- 23304497 | Previous studies exploring this relationship utilized cross-sectional or case-control methodologies to determine the association between “ever” or “current” smoking and lifetime infection with m. tuberculosis as determined by a single tuberculin skin test (tst) result . |
| PubMedID- 26020948 | In addition, previous reports indicate that cross-immunity and the protection provided by infection with m. tuberculosis and use of the bacillus calmette-guerin (bcg) vaccine is associated with ntm infection . |
| PubMedID- 25658539 | High prevalence of human herpesvirus type 8 infection in patients with pulmonary tuberculosis in taiwan. |
| PubMedID- 20888298 | The lung is the main route for infection with mycobacterium tuberculosis bacilli and the primary site of reactivation of latent disease. |
| PubMedID- 23676169 | tuberculosis-infected individuals--14 with latent tuberculosis infection (ltbi) and 12 with active pulmonary tuberculosis (ptb)--using enzyme-linked immunosorbent spot assay, and antibody responses in 42 consecutive individuals, 14 with ltbi and 28 with ptb. |
| PubMedID- 25560475 | The prevalence of hiv infection in patients with tuberculosis is about 8.8%. |
| PubMedID- 26201072 | (b) pulmonary bacilli loads of balb/c mice after 60 days of infection with m. tuberculosis strain h37rv treated during one month with recombinant human hmgb1 (grey bars) or human albumin as a control (white bars) (6 mice per group). |
| PubMedID- 23783070 | Effects of infection and disease with mycobacterium tuberculosis on serum antibody to glucan and arabinomannan: two surface polysaccharides of this pathogen. |
| PubMedID- 24273174 | Human challenge models are routinely used in vaccine development for pathogens such as malaria, influenza, dengue fever, and typhoid ; however, the deliberate infection of humans with m. tuberculosis would not be ethically acceptable. |
| PubMedID- 19935395 | Materials and methods: it is aimed to determine the infection with mycobacterium tuberculosis using acidoresistant bacilli microscopy, tb culture, and histopathological methods in tissue samples that were obtained from lungs of forensic cases whose autopsies had been performed in council of forensic medicine ankara department morgue specialized committee. |
| PubMedID- 23006927 | Irgm1-deficient mice are more susceptible to infection with mycobacterium tuberculosis, m. avium, listeria monocytogenes and salmonella enterica serovar typhimurium, as assessed by both mouse survival and bacterial loads in tissues, whereas irgm3-deficient mice exhibit normal resistance . |
| PubMedID- 24217560 | It has been demonstrated that this protein can differentiate infection with live m. tuberculosis from immunization with killed m. tuberculosis, live bcg, or mycobacterioses other than tb in guinea pigs . |
| PubMedID- 20652022 | However in in vitro settings the role of tnf may be more complex than previously expected in particular when human immune cells are analyzed: we found a significant reduction in the ability to induce tnf in human monocytes and macrophages following ex vivo infection with the m. tuberculosis strain of the index case, when compared to the virulent laboratory strain h37rv. |
| PubMedID- 23239994 | The lack of this cytokine leads to reduced expression of immune mediators and increased susceptibility to primary infection with m. tuberculosis, and depletion of tnf after infection results in reactivation of latent disease , , , . |
| PubMedID- 25915045 | Airways infection with mycobacterium tuberculosis (mtb) is contained mostly by t cell responses, however, mtb has developed evasion mechanisms which affect antigen presenting cell (apc) maturation/recruitment delaying the onset of ag-specific t cell responses. |
| PubMedID- 22838209 | Middle ear infection due to mycobacterium tuberculosis has been reduced from 3-5% to 0.05-0.9% in the last century due to advent of effective anti-tuberculosis therapy. |
| PubMedID- 26135889 | In fact, we confirmed that ablation of sirt2 in bmdm led to increased levels of il-6 upon infection with m. tuberculosis (s2 fig). |
| PubMedID- 25539917 | infection with mycobacterium tuberculosis (mtb) represents one of the most widespread microbial diseases, with nearly one-third of the world's population showing signs of exposure, more than 20 million people actively infected and almost 80% of the population of some countries testing positive in tuberculin tests (1,2). |
| PubMedID- 21698150 | B-irga6−/−mice showed no excess bacterial burden after aerosol infection with m. tuberculosis (figure 2c). |
| PubMedID- 26409284 | In the absence of an effective vaccine to prevent primary infection with mycobacterium tuberculosis and tuberculosis disease, host-directed therapies may offer therapeutic options, particularly for patients with multidrug-resistant and extensively drug-resistant tuberculosis where prognosis is often limited. |
| PubMedID- 22085784 | Molecular analysis of sampled lymph nodes from a ppd positive goat in our study showed an infection with m. tuberculosis as well and not with m. bovis. |
| PubMedID- 21777464 | Flow cytometry analysis of cell surface expression markers cd40, cd54, cd80, cd83, cd86 and hla dr in infected dc revealed significant (p < 0.05) up regulation following infection with m. tuberculosis in comparison to immature dc with no stimulation. |
| PubMedID- 23253353 | infection of macrophages with mycobacterium tuberculosis induces global modifications to phagosomal function. |
| PubMedID- 20808814 | The tuberculin skin test (tst) is used as a standard diagnostic tool to assess for infection with mycobacterium tuberculosis (m.tb). |
| PubMedID- 24755630 | infection with m. tuberculosis (m. tb) is initiated by the few bacilli in a droplet that are inhaled into the alveolus, which results either in establishment of infection and progression to primary tb or, by 4–5 weeks post-infection, elicitation of immune responses that control bacterial replication and result in latent tb. |
| PubMedID- 23147374 | The immunological mechanisms underlying the increased risk of tuberculosis in persons with hiv-1 co-infection, and those that exazerbate in the course of both diseases, are unclear. |
| PubMedID- 25307269 | The bcg vaccine is effective in children but not recommended in adults and elderly patients due to an associated low risk of infection with mycobacterium tuberculosis and variable effectiveness of the vaccine. |
| PubMedID- 24640721 | The effectiveness of methylglucamine acridonacetates in integrated treatment of chronic hepatitis c, tuberculosis with hiv infection background, chronic brucellosis, arboviral diseases, including west nile fever, as well as influenza and acute respiratory infections are shown. |
| PubMedID- 25143340 | Intranasal administration of mycobacterium bovis bcg induces superior protection against aerosol infection with mycobacterium tuberculosis in mice. |
| PubMedID- 25785445 | Background: to evaluate interleukin (il)-2 and interferon (ifn)-gamma secreting t-cells in parallel for the differentiation of latent infection with mycobacterium tuberculosis infection (ltbi) from active tuberculosis. |
| PubMedID- 20937781 | Beginning 2 weeks after aerosol infection with mycobacterium tuberculosis, total pa-824 doses from 144 to 4,608 mg/kg were administered as 3, 4, 8, 12, 24, or 48 divided doses over 24 days. |
| PubMedID- 23372824 | In other studies, co-infection with tuberculosis was associated with increased mortality in children receiving art . |
| PubMedID- 23556450 | Aim: we examined whether hla-drb1*1501 and four vdr snps influence the macrophage response to infection with mycobacterium tuberculosis (mtb) via innate immune versus drug treatment or drug delivery mechanisms. |
| PubMedID- 25938227 | The centers for disease control and prevention (cdc) recommend igras be used as tst as aids in diagnosing infection with m. tuberculosis, and igra is preferred particularly for persons that have low rates of returning to have tst read or those who have received bcg vaccination 6. |
| PubMedID- 23056438 | Another of these proteins, encoded by rv0386, was shown to have an alternative substrate-binding mechanism regarding its cyclase activity , and infection with m. tuberculosis that do not express rv0386 resulted in a decreased bacterial-derived intramacrophage camp, tumour necrosis factor- (tnf) production and bacterial survival . |
| PubMedID- 25400917 | Bacterial loads in the lung of infected mice were evaluated at different time points after infection with m. tuberculosis h37rv as described . |
| PubMedID- 26347586 | Approximately one third of the world's population has latent infection with mycobacterium tuberculosis 1. |
| PubMedID- 24158955 | However, the il-1 receptor also binds il-1α, which can be released upon inflammasome activation, and a role for il-1α during infection with m. tuberculosis cannot be ruled out. |
| PubMedID- 20525402 | Background: interferon gamma is a major macrophage-activating cytokine during infection with mycobacterium tuberculosis, the causative pathogen of tuberculosis, and its role has been well established in animal models and in humans. |
| PubMedID- 23253780 | Interferon-gamma release assays (igras) are emerging tools for the detection of infection with m. tuberculosis with some advantages compared to tst, but are more costly. |
| PubMedID- 23649713 | In this context, it is worth noting that coinfection with m. tuberculosis bacilli can accelerate aids progression, since this bacterium can promote the replication of hiv and infection of cd4+ t cells . |
| PubMedID- 24260726 | Co-infection with hiv and tuberculosis, more than 40% skin involvement, and severe sepsis have been found to be poor prognostic factors . |