PedAM
Pediatric Disease Annotations & Medicines
| Disease | tuberculosis |
| Symptom | |infection |
| Sentences | 645 |
| PubMedID- 23682439 | Hiv clinical stage 3 or 4, co-infection with tuberculosis and hepatitis c infection and a cd4+ t cell count of <50 cells/microl were risk factors for ocular disease in hiv/aids patients. |
| PubMedID- 25350002 | Severity of bovine tuberculosis is associated with co-infection with common pathogens in wild boar. |
| PubMedID- 22820541 | Background: human immunodeficiency virus (hiv) infection increases the risk of poor outcomes in active tuberculosis. |
| PubMedID- 22021753 | We must emphasise that some individuals who completed all steps of the test, including the re-evaluation after 1 year, and were identified as recent converters (indicative of recent infection with m tuberculosis), did not take up the offer of an appointment to discuss chemoprophylaxis. |
| PubMedID- 24555539 | Children are highly susceptible to infection with m. tuberculosis, and once infected, are at much higher risk of progression to tb than adults 4. |
| PubMedID- 23113903 | After 24 h of infection with m. tuberculosis, the cells did not recover their basal morphology and still presented abundant vacuoles (figure 5g). |
| PubMedID- 22275911 | While staurosporine treatment and 20a11 infection triggered caspase-1 activation of macrophages, m. tuberculosis h37rv and complemented 20a11 clone were able to suppress caspase-1 activation. |
| PubMedID- 23077694 | Contact investigation is recommended by the centers for disease control and prevention as a strategy to identify, examine, and evaluate all persons who are at risk of infection with tuberculosis (tb) due to recent exposure to a diagnosed or suspected index case (1). |
| PubMedID- 21092301 | Furthermore, tb-hiv coinfected children in eastern europe often have severe presentation of tb disease , in our study co-infection with extra-pulmonary m. tuberculosis infection was reported for 13% of children with aids; however, we may have underestimated the true prevalence of tb in the cohort. |
| PubMedID- 21115690 | Preferential infection and depletion of mycobacterium tuberculosis-specific cd4 t cells after hiv-1 infection. |
| PubMedID- 22566941 | Following raw cell infection with m. tuberculosis var. |
| PubMedID- 25381367 | Likewise, laboratory mice in brazil and mexico show less susceptibility to infection with m. tuberculosis and also less protection from bcg . |
| PubMedID- 23785280 | infection with mycobacterium tuberculosis (mtb), the causative agent of tb, is usually acquired via inhalation of airborne droplets containing the bacteria. |
| PubMedID- 20221700 | infection with mycobacterium tuberculosis (mtb) can cause different outcomes in hosts with variant genetic backgrounds. |
| PubMedID- 22567094 | Furthermore, we have demonstrated the protective efficacy of both plasmid dna expressing mpt83 and rmpt83 protein vaccine in adjuvant against aerosol infection with m. tuberculosis in mice. |
| PubMedID- 21767990 | Human infection with mycobacterium tuberculosis (m.tb) is asymptomatic in most people and controlled, at least in part, by a t cell response comprising cd4 and cd8 cells, and expression of the th1 cytokines, ifn-γ and tnf-α.1 however, this control fails in approximately 9.3 million people worldwide who develop clinical tuberculosis (tb) each year.2 sites of established disease in humans represent compartments of failed immune control, offering the opportunity to study immune mediators and understand mechanisms of immune control in humans. |
| PubMedID- 21372049 | Upon infection via inhalation of droplets containing m. tuberculosis, bacteria are taken up by patrolling alveolar macrophages. |
| PubMedID- 24459398 | Superior protection against experimental infection with virulent m. tuberculosis, instilled into the lungs of vaccinated mice, was seen when the vaccine was administered intranasally rather than subcutaneously. |
| PubMedID- 22935849 | Pcr detection of co-infection with mycobacterium tuberculosis and mycobacterium avium in aids patients with meningitis. |
| PubMedID- 20441613 | For example, genome-wide rna interference screens targeting human genes in the context of infection with hiv and tuberculosis have been carried out. |
| PubMedID- 21572600 | Co-infection with m. tuberculosis and hiv (tb/hiv), especially in the hbcs of sub-saharan africa and south eastern asia, multidrug-resistant (mdr) and extensively drug-resistant (xdr) tb in all regions, make control activities more complex and demanding. |
| PubMedID- 23904584 | Efficacy tends to be higher among individuals who respond negatively or weakly to a tuberculin skin test (tst, inoculation of a multi-antigenic purified mycobacterial protein derivative that stimulates a delayed-type hypersensitivity response) 7, suggesting that they have not previously been exposed to infection with mycobacterium tuberculosis or other non-tuberculous mycobacteria (ntms). |
| PubMedID- 25819037 | Co-infection with tuberculosis (tb) and hiv is common in low-income countries. |
| PubMedID- 21953458 | Total rna was isolated from 5 × 106 thp1 cells 6, 12, 48, and 90 h after infection with m. tuberculosis and from uninfected cells as control for the experiment using trizol reagent (invitrogen) in accordance with the manufacturer's instructions. |
| PubMedID- 22548067 | The increased risk of reactivation or infection with m. tuberculosis is a consideration when balancing the risks and benefits of corticosteroids in high prevalence regions . |
| PubMedID- 22844392 | We used multiple doses of mip for immunotherapy as pre-existent th2-driving physiological condition like infection with m. tuberculosis might overshadow the efficacy of a single dose of immunomodulator that could otherwise be effective in eliciting strong anti-tb th1 response. |
| PubMedID- 20941341 | Despite our increasing knowledge, several key questions about latent infection and reactivation of m. tuberculosis remain unanswered. |
| PubMedID- 21165340 | Very recently, mice deficient in nitric oxide synthase 2 have been reported to manifest human-like granumolas after dermal infection with m. tuberculosis . |
| PubMedID- 22088322 | The present study tested the hypothesis that the scavenger receptor sr-a modulates granuloma formation in response to pulmonary infection with mycobacterium tuberculosis (mtb). |
| PubMedID- 23457650 | infection of mice with mycobacterium tuberculosis followed by repeated bcg injections led to an il-17a–dominated response, which was refractory to regulation by ifnγ . |
| PubMedID- 26528819 | In addition, infection with high doses of mycobacterium tuberculosis resulted in rapid mortality in tlr2-deficient mice . |
| PubMedID- 22732919 | Background: one-third of the world's population has latent infection with mycobacterium tuberculosis, and 10%-15% of cases of reactivation occur at extrapulmonary sites without active pulmonary tuberculosis. |
| PubMedID- 24009502 | For example, the sst1 susceptible mouse strain is clearly compromised in its ability to control the bacterial burden during infection with m. tuberculosis and l. monocytogenes. |
| PubMedID- 25758696 | Hiv testing rates and co-infection among patients with tuberculosis in south-eastern sydney, 2008-2013. |
| PubMedID- 24722144 | Sera from male non-castrated mice were used to determine testosterone by elisa in the indicated time points after intratracheal infection with m. tuberculosis strain h37rv. |
| PubMedID- 20487550 | The world health organization (who) estimates that 489,000 cases of multi-drug resistant tb (mdr-tb), defined as infection with a mycobacterium tuberculosis (mtb) strain resistant to at least isoniazid (inh) and rifampin (rif), occur annually, predominantly in eastern europe and asia 1. |
| PubMedID- 23304792 | infection with mycobacterium tuberculosis is a well-described global phenomenon, but other mycobacterial species are increasingly shown to be the cause of both pulmonary and extrapulmonary infection and are managed differently from m. |
| PubMedID- 23233675 | Nevertheless, despite observing increased levels of mrna transcripts and enhanced levels of membrane-bound and intracellular tnf-α protein, we were unable to detect significant changes in secreted tnf-α protein upon infection of dcs with m. tuberculosis (supplemental fig. |
| PubMedID- 24320132 | We discuss here the modern bioanalytical techniques that can be used to discover biomarkers of infection with mycobacterium tuberculosis, focusing on techniques using gc. |
| PubMedID- 20463893 | To broaden our knowledge on the dynamics of tb lung inflammation dependent upon genetic susceptibility of the host, we used flow cytomentry to compare accumulation of different leukocyte populations in the lungs of b6 and i/st mice following aerosol infection with 100 m. tuberculosis cfu. |
| PubMedID- 20625513 | Murine infection with mycobacterium tuberculosis results in a sustained and eventually fatal bacterial burden, which does not reflect the low bacterial burden found in chronically infected humans , . |
| PubMedID- 21143966 | Where there is more than one numerical figure per locus implies existence of more than one mtb strain in the sample, indicating multiple strain infection with m. tuberculosis (patient samples a, b, c, and g). |
| PubMedID- 21459676 | Ip-10 has potential as a diagnostic marker for infection with mycobacterium tuberculosis, with comparable accuracy to quantiferon-tb gold in-tube test (qft-it). |
| PubMedID- 23320781 | Th1 immune responses (ifn-γ, il-12) are required for protection against infection with m. tuberculosis while a raised th2-like cytokine profile (such as, il-10, il-4 and tgf-β) is implicated with disease progression in tb. |
| PubMedID- 20532047 | Moreover, examination of fucosyltransferase-vii and-iv double knockout mice (ftdko) for immunity following infection with mycobacterium tuberculosis found that ftdko mice had significantly diminished numbers of activated cd8 and cd4 t cells in the draining lymph node of the lung (mediastinal lymph node, medln), but had effective granuloma responses and similar recruitment of activated t cells into the lung at later stages of infection . |
| PubMedID- 23923111 | Since the increase in hiv infection rate leads to increase in tuberculosis disease, there is need to re-examine the strategies for their effective control. |
| PubMedID- 22496656 | For example, the course of hiv-1 related immunodeficiency is also known to be accelerated by active infection with mycobacterium tuberculosis (mtb) , and in vitro studies have demonstrated that mtb-infection of mdms subsequently infected with hiv-1 produce increased levels of virus as compared to mdms uninfected with mtb . |
| PubMedID- 25633896 | However, it was not until 1996 when infection with mycobacterium tuberculosis was identified in a herd of circus elephants that significant research into this disease began. |
| PubMedID- 23475311 | Four hours after infection with m. tuberculosis, macrophages were washed twice with rpmi 1640 containing 20 mm hepes buffer and then maintained in rpmi 1640 containing 10% non–heat-inactivated human ab serum and 20 mm hepes buffer. |
| PubMedID- 20822521 | Uaps are generally either untrained or have limited training in specific disease areas such as diarrhea, malaria, acute respiratory infection, integrated management of childhood illness, aids, tuberculosis, and safe motherhood. |