PedAM
Pediatric Disease Annotations & Medicines
| Disease | tuberculosis |
| Symptom | |infection |
| Sentences | 645 |
| PubMedID- 22024399 | Background: dendritic cells (dcs) connect innate and adaptive immunity, and are necessary for an efficient cd4+ and cd8+ t cell response after infection with mycobacterium tuberculosis (mtb). |
| PubMedID- 23287128 | Four weeks after low-dose aerosol infection either with m. tuberculosis or m. bovis, mice were treated 5 days/wk with 5-cl-pza, at doses ranging from 37.5 to 150 mg/kg, either alone or in combination with isoniazid and rifampicin. |
| PubMedID- 24367768 | The advent of the aids epidemic and the introduction of immunosuppressive therapies dramatically increased the number of people at risk of infection not only with m. tuberculosis but also with other mycobacterium species that otherwise would not cause disease. |
| PubMedID- 23251798 | The protective potential role of th17 cells during the early phase of infection with m. tuberculosis is unknown . |
| PubMedID- 24659544 | Recommendations on treatment of latent infection with m. tuberculosis including treatment of contacts of mdr-tb patients have been published by the centers for disease control and prevention (cdc) . |
| PubMedID- 22570667 | Rbcg::ab strain could provide the strongest short-term and long-term protection in the lung against intravenous infection with virulent m. tuberculosis than rbcg::261 control and other two rbcg strains overexpressing single antigen. |
| PubMedID- 21956656 | Owing to our lack of understanding of the factors that constitute protective immunity during natural infection with mycobacterium tuberculosis (mtb), there is an urgent need to identify host biomarkers that predict long-term outcome of infection in the absence of therapy. |
| PubMedID- 26419483 | Chimpanzees (pan troglodytes schweinfurthii) and baboons (papio anubis) in gombe national park, tanzania, were screened for infection with pathogens of the mycobacterium tuberculosis complex using fecal is6110 pcr; none was positive. |
| PubMedID- 22699225 | At this time an infection with mycobacterium tuberculosis could be detected in both cerebrospinal fluid and abscess material of the spine suggesting a landouzy sepsis, tuberculous meningitis/encephalitis and the suspicion of an underlying pott's disease. |
| PubMedID- 20644306 | Background and purpose: it has been shown that chemokine secretion upon infection with mycobacterium tuberculosis is influenced by the virulence of the strain, and it is suggested that virulence-associated differences in chemokine secretion contribute to the failure in containing the infection due to poor granuloma formation. |
| PubMedID- 26241963 | The different manifestations of infection with mycobacterium tuberculosis (m.tb) reflect the balance between the bacilli and host defense mechanisms 4. |
| PubMedID- 23226773 | Ethambutol, isoniazid and rifamycins (including rifampicin and rifabutin) were considered to be classic drugs against infection with mycobacterium tuberculosis, and trials of antituberculosis drugs were included in the meta-analysis. |
| PubMedID- 21799772 | However, in epidemiologic studies and tb vaccine trials in humans, protection against tb has only been observed either after natural infection with m. tuberculosis or non-tuberculous mycobacteria (ntm) , , , , or after immunization with live or inactivated whole cell mycobacterial vaccines , , , , , , , , . |
| PubMedID- 24224058 | Human infection with mycobacterium tuberculosis results in the influx of inflammatory cells to the lung in an attempt to wall off bacilli by forming a granuloma. |
| PubMedID- 26294972 | Most cases of tb in patients receiving immunosuppressive therapy have been attributed to reactivation rather than de novo infection with mycobacterium tuberculosis . |
| PubMedID- 24708540 | Several studies show that infection with m. tuberculosis increases the replication of hiv in mononuclear cells . |
| PubMedID- 24555577 | On a global scale, a substantial proportion of the morbidity and mortality caused by tuberculosis (tb) is attributed to hiv co-infection and the emergence of drug resistance 1. |
| PubMedID- 20074686 | infection with mycobacterium tuberculosis continues to be a major public health burden in most developing parts of the world and efforts to develop effective strategies for containing the disease remain a priority. |
| PubMedID- 24093045 | Highlight that the diminished proinflamatory cytokine capacity of the newborn following infection with m. tuberculosis allows bacterial spread. |
| PubMedID- 22566907 | For example, lung infection with mycobacterium tuberculosis in cd44-deficient mice led to increased neutrophil infiltration with no differences in leukocyte entry or bacterial clearance (kipnis et al., 2003). |
| PubMedID- 21745684 | Conclusions: selective loss of t(h)1/t(h)17 cells may be a risk factor for the development of active tuberculosis in patients with hiv-1 infection and might be a useful biomarker in the development of tuberculosis vaccines. |
| PubMedID- 21327127 | New strategies to control infection with mycobacterium tuberculosis, the causative agent of tuberculosis, are urgently required, particularly in areas where acquired immunodeficiencies are prevalent. |
| PubMedID- 20544012 | As shown on the chart in figure s1, infection with m. tuberculosis was performed 18 days or 42 days after the toxocara canis or s. mansoni infection, respectively. |
| PubMedID- 26578819 | The aim of the present study was to look for associations between polymorphisms in vdr and nramp1 genes and susceptibility to infection and disease with mycobacterium tuberculosis, as indicated by a positive tst, and the development of tb in the venezuelan population. |
| PubMedID- 21750585 | The latter accounts for the fact that cytosolic organisms induce ifn-β during infection with m. tuberculosis, which has been shown to be an important host defense component during infection with this organism. |
| PubMedID- 26518735 | Mycobacterium bovis infection, the cause of bovine tuberculosis (btb), is endemic in wildlife in the kruger national park (knp), south africa. |
| PubMedID- 25336729 | This is in contrast to findings from cape town, where the annual risk of infection with m. tuberculosis is much higher . |
| PubMedID- 21244656 | The economically vulnerable are more likely to be exposed to conditions that predispose to infection with mycobacterium tuberculosis and that propagate progression to disease . |
| PubMedID- 25135824 | Ltbi is defined as a complex clinical condition in which an infection with m. tuberculosis persists in a subclinical status with minimal replication. |
| PubMedID- 23602851 | However, co-infection of hiv with mycobacterium tuberculosis and other microbial and viral agents has introduced added complications to this pandemic, requiring favorable drug-drug interaction profiles for antiviral therapeutics targeting hiv. |
| PubMedID- 25975852 | It has been suggested that infection with corynebacterium pseudotuberculosis, the pathogen responsible for caseous lymphadenitis (cla), might interfere with diagnostic testing for tuberculosis (tb), due to antigenic similarities between this particular type of bacterium and those expressed by mycobacteria. |
| PubMedID- 22980546 | Among the patient population studied, the hiv infection increased the risk of developing severe tuberculosis (adjusted odds ratio: 2.9; 95%ci: 1.2-6.8). |
| PubMedID- 26343850 | In the karonga/malawi bcg trial, 57% of cases of clinical tuberculosis were directly attributable to hiv infection . |
| PubMedID- 24523814 | The t cell responses to esat-6 and cfp-10 are also not completely specific for infection with m. tuberculosis complex and may result from certain ntm infections. |
| PubMedID- 24311770 | Latent infection with mycobacterium tuberculosis (ltbi) is defined by the presence of m. |
| PubMedID- 26573524 | M. tuberculosis subpopulation associated with latent infection in humans is believed to be in a dormant state characterized by low metabolic status and transient inability to grow and proliferate . |
| PubMedID- 23569448 | Pcr examination confirmed infection with mycobacterium tuberculosis (fig. |
| PubMedID- 24695805 | 3) co-infection with pulmonary tuberculosis increases the risk of death in hiv-associated sjs/ten 10-fold. |
| PubMedID- 24732815 | Art eligibility was defined based on 2 standards: (1) 2011 kenya eligibility criteria for art initiation: cd4 infection with active tuberculosis and (2) 2013 world health organization (who) eligibility criteria for art initiation: cd4 infection with active tuberculosis, currently pregnant or breastfeeding, and infected partners in serodiscordant relationships. |
| PubMedID- 24130493 | However, only 10% of latent infections lead to active tuberculosis, indicating the importance of host immune defense against mycobacterial infection 2. |
| PubMedID- 21234341 | Primary infection with m. tuberculosis leads to clinical disease in only ~10% of individuals. |
| PubMedID- 26484340 | infection with mycobacterium tuberculosis bacilli may result in latent tuberculosis infection (ltbi), a carrier state where patients are neither symptomatic nor contagious (12). |
| PubMedID- 21738523 | (a) macrophage expression data following infection with m. tuberculosis reveals overlap of upregulated genes identified in three macrophage models of m. tuberculosis infection (schnappinger et al., 2003; rachman et al., 2006a; fontán et al., 2008). |
| PubMedID- 20634980 | Recently, s1p has been shown to induce antimicrobial activity with both in vitro and in vivo animal infection models of mycobacterium tuberculosis , , . |
| PubMedID- 24044166 | Clinical experience using rifabutin for treating infection with mycobacterium tuberculosis in elderly japanese patients. |
| PubMedID- 21571261 | Fatty acid profile during the differentiation and infection with mycobacterium tuberculosis of mononuclear phagocytes of patients with tb and healthy individuals. |
| PubMedID- 24349510 | In people with latent tuberculosis infection, the risk of becoming active tuberculosis is approximately 5% - 10% during the life time. |
| PubMedID- 23738776 | The macrophage activating cytokines tnfα and ifnγ promoted the phagosomal accumulation of zinc in mycobacterium avium-infected mouse macrophages, and phagosomal zinc also accumulated over time in response to infection with mycobacterium tuberculosis . |
| PubMedID- 23675482 | Protection against infection with m. tuberculosis involves different cellular mechanisms , . |
| PubMedID- 20306981 | One case represented dual infection with mycobacterium tuberculosis and cryptococcus. |