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PedAM

Pediatric Disease Annotations & Medicines




Disease tuberculosis
Symptom |infection
Sentences 645
PubMedID- 25031852 Tb disease can result from a rapidly progressive disease following recent infection with mycobacterium tuberculosis or from reactivation of a past latent tb infection.
PubMedID- 20847080 Interferon-gamma release assays (igras) are now established for the immunodiagnosis of latent infection with mycobacterium tuberculosis in many countries.
PubMedID- 23448601 Background: infection of humans with mycobacterium tuberculosis (mtb) results in latent tuberculosis infection (ltbi) in 90-95% of immune competent individuals, with no symptoms of active disease.
PubMedID- 23898922 No longer mainly a complication after pulmonary infection with mycobacterium tuberculosis, diverse disease processes and mechanisms have been demonstrated to result in the chronic cough, purulent sputum production, and airway dilation that characterize this disease.
PubMedID- 24663056 Upon invasion to a host, the mtb can either be eliminated by host immune responses, lie dormant for a long term of infection that may lead to a latent tuberculosis infection, or progress to active clinical disease by break-down of the immune defense.
PubMedID- 24690344 Since the disease outcome following infection with m. tuberculosis may be influenced by confounding factors like age, sex and hiv, multivariable logistic regression was used with m. tuberculosis genotype, age, sex and hiv status entered into the model to adjust for these confounding variables.
PubMedID- 21085569 Although hiv infection, along with previous sub-optimal tuberculosis treatment programmes, may have contributed to the initial emergence of tuberculosis drug resistance, the high community hiv prevalence in khayelitsha does not appear to be a significant factor selectively driving dr-tb transmission in this setting.
PubMedID- 23565372 1 during addison's time, infection especially due to mycobacterium tuberculosis was the main etiological factor, which has given way to auto-immune adrenalitis over last few decades.
PubMedID- 20582178 1 pneumonia due to b. pseudomallei itself is a rare condition and co-infection with tuberculosis is extremely rare.
PubMedID- 20178619 Depending on the epidemiological situation and the local infectious pressure, the probability of development of clinical disease after infection with mycobacterium tuberculosis varies.
PubMedID- 23118880 Conversely, higher multiplicities of infection with m. tuberculosis resulted in necrosis-like cell death through a caspase-independent mechanism , and several studies report that virulent strains of m. tuberculosis induce necrotic death of the macrophage , , , .
PubMedID- 26343849 Yet most human hosts are able to resolve the granulomatous lesions of primary infection with m. tuberculosis, which are often marked by foci of calcification within the lung parenchyma and hilar lymph nodes to form a ghon complex .
PubMedID- 24350246 Despite 100 years of research, infection with mycobacterium tuberculosis (mtb) is still a major health problem worldwide and one of the main causes of human death by a particular infectious agent.
PubMedID- 26126176 Therapy is based on nonspecific immunosuppression, such as corticosteroids and tnfα blocking agents, despite the fact that these treatments are well known to be associated with severe side effects and toxicity, leaving patients immunocompromised and susceptible to opportunistic infection or reactivation of latent tuberculosis .
PubMedID- 23970604 Co-infection with tuberculosis was one of the most important prognostic factors of progression to aids and antiretroviral treatment was found to be an effective measure in suppressing hiv viral replication and improving the survival of patients living with hiv.
PubMedID- 20488517 Human infection with mycobacterium tuberculosis can progress to active disease, be contained as latent infection, or be eradicated by the host response.
PubMedID- 20967279 Children are susceptible to infection with m. tuberculosis in the community, at greater risk of progressing to active disease when infected at a very young age , .
PubMedID- 21622974 infection with drug-resistant m. tuberculosis strains is extremely serious, prolonging treatment time, decreasing the probability of cure and increasing the cost of treatment.5 the current anti-tb chemotherapy must be administered for 6 months for drug-susceptible strains and for ≥2 years for multidrug-resistant (mdr) or extensively drug-resistant (xdr) infections.
PubMedID- 21214913 The selective dot county had a higher percentage of tuberculosis patients with hiv co-infection than the universal dot county (15% n = 183 vs. 11% n = 58, p = 0.03), with this difference was greatest among clustered patients (19% n = 135 vs. 13% n = 39, p < 0.0001); the prevalence of hiv in the general populations of the two counties is unknown.
PubMedID- 22865977 6 in the present case there was a combined infection with m. tuberculosis and f. pedrosoi involving the cranium and the rib cage.
PubMedID- 24130966 The production of il-1beta during the infection with mycobacterium tuberculosis (mtb) is important for successful host immune defense.
PubMedID- 23166708 We estimate that 53.6% (95% ci: 44.6–62.8) of the samples tested were free from infection with m. tuberculosis and 15.9% (97.5% ci: 9.8 - to 24.0) tested positive on all five tests.
PubMedID- 24517907 Decreased glutathione and decreased macrophage defense against intracellular infection with mycobacterium tuberculosis occurs in the macrophages of individuals with hiv .
PubMedID- 24166044 Epidemiologic studies of co-infection with tuberculosis (tb) and intestinal parasites in humans have not been extensively investigated in china.
PubMedID- 21992484 In 2005, stewart et al demonstrated that both acr proteins contribute to persistent infection with m. tuberculosis, and suggested that manipulation of acr expression can influence the host response to infection .
PubMedID- 23374532 Infliximab treatment has recently emerged as a safe and effective method of inducing and maintaining remission of crohn’s disease , but the immunosuppression sometimes results in unexpected complications, such as infection with mycobacterium tuberculosis, sepsis, severe pneumonia, severe liver dysfunction, and leucopenia.
PubMedID- 23091578 Although the initial microbiological examination of the first aspirate being inconspicuous, a current quantiferon-test 7 showed a positive reaction as an indication of a latent or active infection with mycobacterium tuberculosis (m. tbc), mycobacterium kansasii, mycobacterium szulgai or mycobacterium marinum.
PubMedID- 25453230 Unfortunately, the onset of the t cell response after aerosol infection with mycobacterium tuberculosis (mtb), the bacterium that causes tb, is exceedingly slow, and systemically administered vaccines only modestly accelerate the recruitment of effector t cells to the lungs.
PubMedID- 20692169 This study suggests that cns infection with mycobacterium tuberculosis is an important cause of nmo.
PubMedID- 22768165 In the present study we show that the fusion protein hyvac4 (h4), consisting of the mycobacterial antigens ag85b and tb10.4, given in the adjuvant ic31® or dda/mpl effectively boosted and prolonged immunity induced by bcg, leading to improved protection against infection with virulent m. tuberculosis (m.tb).
PubMedID- 24816692 Boxes represent the proportions of the modeled population that are susceptible to infection, latently infected with m. tuberculosis, in active tb disease, under treatment, or cured.
PubMedID- 26121261 It is estimated that a minimum infective dose of <10 cfu may cause respiratory infection with m. tuberculosis in humans .
PubMedID- 24373112 infection with mycobacterium tuberculosis (mtb) can result in active tb or, more commonly latent tb 1.
PubMedID- 23487151 The incidence of tuberculosis in patients with hiv infection in asian countries where tb is endemic showing the growing sensitivity of aids to the tb germs and more than 9 percent of tb cases with hiv occurs in these countries (5).
PubMedID- 23577011 This is also relevant in vivo, as mice lacking the autophagy protein atg5 in myeloid cells secrete higher levels of il-1α, il-12p70, cxcl1, and il-17 in response to infection with mycobacterium tuberculosis (castillo et al., 2012).
PubMedID- 20388213 The situation is further aggravated by the increased susceptibility of human immunodeficiency virus (hiv)-positive people to infection with mycobacterium tuberculosis .
PubMedID- 25449228 The incidences of infection with mycobacterium tuberculosis and cryptococcus neoformans in immunocompromised patients have increased, but there are few documented cases of their coexistence.
PubMedID- 22768155 infection with strains of m. tuberculosis with reduced susceptibility to no did not correlate to the final clinical outcome according to who (cured, died, treatment failure, defaulter or transferred out; table 1), but there was a tendency to a lower rate of weight gain after 8 weeks of treatment (83% (20/24) vs. 100% (25/25), p = 0.05).
PubMedID- 21569594 Communicable diseases have been documented to cause the highest morbidity in refugee, migrant and displaced populations, mainly due to diarrheal diseases such as cholera and dysentery; acute respiratory infection, measles, malaria, with hiv/aids and tuberculosis becoming increasingly important .
PubMedID- 20185096 The analysis suggests that there is reason to doubt the value of actively screening air passengers for infection with mycobacterium tuberculosis and that the resources used might be better spent addressing other priorities for the control of tuberculosis.
PubMedID- 22118176 The prevalence of infection with mycobacterium tuberculosis and non-tuberculous mycobacteria (ntm) in hiv-infected patients in china is unknown.
PubMedID- 24278312 Mice were killed over the course of infection with h37rv m. tuberculosis to determine the bacterial load within their lungs.
PubMedID- 24500401 infection with m. tuberculosis may result in several outcomes including latent infection and active disease, which can be confined to the lungs or manifest at distant sites.
PubMedID- 25992610 Correction: co-infection with mycobacterium tuberculosis impairs hiv-specific cd8+ and cd4+ t cell functionality.
PubMedID- 21533159 However, light-deficient mice display normal immune responses following infection with mycobacterium tuberculosis or influenza a , suggesting that light may regulate some cellular responses whilst being superfluous for others.

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