PedAM
Pediatric Disease Annotations & Medicines
| Disease | tuberculosis |
| Symptom | |infection |
| Sentences | 645 |
| PubMedID- 25784490 | During active and chronic infection with m. tuberculosis, the accumulation of tg-rich lipid bodies in foamy macrophages is used as an energy source for the intracellular pathogen32. |
| PubMedID- 22377140 | Background: the non-adherence to tuberculosis treatment is associated with increased infection, antibiotic resistance, increased costs and death. |
| PubMedID- 21592820 | A well-known association between vitamin d(3) and infection with mycobacterium tuberculosis has previously been reported, but little is known regarding the underlying mechanisms. |
| PubMedID- 26374119 | One-third of the global population is latently infected (latent tb infection ltbi) with mycobacterium tuberculosis, thus facing the risk of developing active tb during their lifetime. |
| PubMedID- 23848406 | Nevertheless, the role of apoptosis during infection with mycobacterium tuberculosis, the causative agent of human tuberculosis, is subject of an intense debate and still remains unclear. |
| PubMedID- 25490545 | Latent infection with dormant mycobacterium tuberculosis is one of the major reasons behind the emergence of drug-resistant strains of the pathogen worldwide. |
| PubMedID- 25779327 | Upon infection with mycobacterium tuberculosis, pmn are attracted to the site of infection along an interleukin 8 gradient. |
| PubMedID- 20386605 | As a chest x-ray is able to detect old calcified lesions, it is traditionally considered that, upon infection with m. tuberculosis, an initial dissemination of lesions, which might evolve towards calcification, takes place before the immune response is triggered . |
| PubMedID- 23672065 | The awareness of patients with tuberculosis associated with hiv-infection about this pathology. |
| PubMedID- 24710359 | The sfu readout clearly demonstrated the response to infection with tuberculosis to be significantly greater than that seen before infection in both bcg-vaccinated and unvaccinated animals. |
| PubMedID- 20837713 | These studies show that infection of macrophages with mycobacterium tuberculosis or m. |
| PubMedID- 26180808 | In the united states where infection due to m. tuberculosis is uncommon, antibody to the common mycobacterial antigen lipoarabinnomanin rises with age and supports widespread age-related acquisition of asymptomatic ntm infection . |
| PubMedID- 23671579 | tuberculosis (tb), owing to mycobacterium tuberculosis infection, still remains as a major global health problem. |
| PubMedID- 22472030 | Although papulonecrotic tuberculid is an uncommon cutaneous manifestation of tuberculosis (tb) associated with mycobacterium tuberculosis infection, the simultaneous occurrence of papulonecrotic tuberculid and erythema induratum is even rarer. |
| PubMedID- 19854855 | For example, although tnf-α has been found to be involved in the formation and maintenance of granulomas during infection with mycobacterium tuberculosis, there is little evidence to suggest involvement of il-6 in granuloma preservation . |
| PubMedID- 22253798 | Another clinical example could include infection with mycobacteria tuberculosis, where the initial pulmonary exposure to the organism results in mild, localized disease which is checked by the immune system but results in an immunologic détente, in which the relatively dormant organism is now encased within a granuloma, precluding continued replication but failing to fully eradicate the threat. |
| PubMedID- 24330755 | This includes rates of co-infection with tuberculosis and other opportunistic infections. |
| PubMedID- 21040518 | Data from animal models suggest that leptin plays a role in the early immune response to pulmonary infection with mycobacterium tuberculosis, most likely by mediating an effective interferon-γ driven th1 response, adequate lymphocyte trafficking and granuloma formation . |
| PubMedID- 25730945 | The patient was diagnosed as pulmonary mycobacterium kansasii infection and treatment with anti-tuberculosis drugs including rfp resulted in a good clinical response. |
| PubMedID- 21392425 | Although serologic tests can detect infection with m. tuberculosis years earlier than trunk-wash cultures (9), negative serologic results cannot exclude the possibility of infection. |
| PubMedID- 22429048 | Macaques are susceptible to infection with different strains of mycobacterium tuberculosis (mtb), producing the full spectrum of disease conditions, including latent infection, chronic progressive infection, and acute tb, depending on the route and dose of infection. |
| PubMedID- 23919057 | Our case was a case of pulmonary tuberculosis with hiv infection and one of the contributing factors for skin necrosis could be hypercoagulability secondary to hiv and tuberculosis. |
| PubMedID- 25657138 | A dual infection with mycobacterium tuberculosis and mycobacterium avium was diagnosed with multiplex polymerase chain reaction (mpcr). |
| PubMedID- 22675469 | Il-22 was thus shown to be important for inducing a protective host immunity to the extracellular gram-negative pathogens k. pneumoniae in the lung and c. rodentium in the intestine , but did not have an important role in the host defense against infection with m. tuberculosis, mycobacterium avium, l. monocytogenes and s. mansoni, . |
| PubMedID- 22876078 | Additionally, hiv infection is associated with primary multi-drug resistant-tuberculosis (96–98). |
| PubMedID- 25623609 | In total, 82 patients (82/236, 34.7%) had infection with an m. tuberculosis isolate exhibiting some form of drug resistance. |
| PubMedID- 24168831 | In this study, clinical features and outcomes of patients who fulfilled the criteria for bm infection due to mycobacterium tuberculosis (mtb) and non-tuberculous mycobacteria (ntm) at a medical centre in taiwan from 2001 to 2009 were investigated. |
| PubMedID- 22879892 | Indeed, mice deficient in autophagy and autophagy related genes were found to be more susceptible to infection with m. tuberculosis, and human mononuclear cells with certain polymorphisms in autophagy related genes displayed an impaired ability to control m. tuberculosis growth , , thus suggesting that polymorphisms in autophagy and autophagy related genes may be associated with tb. |
| PubMedID- 23436998 | Natural infection with mycobacterium tuberculosis (mtb) occurs by inhalation, followed by invasion of resident alveolar macrophages that provide the major initial replication niche for the pathogen. |
| PubMedID- 21825018 | Preexisting helminth infection induces inhibition of innate pulmonary anti-tuberculosis defense by engaging the il-4 receptor pathway. |
| PubMedID- 25617816 | Since the introduction of biologics for the treatment of rheumatoid arthritis (ra), psoriatic arthritis (psa), ankylosing spondylitis (as), and psoriasis (pso) an increased risk of tuberculosis (tb) reactivation in patients with latent tuberculosis infection (ltbi) has been recorded for anti-tnf agents, while a low or absent risk is associated with the non-anti-tnf targeted biologics. |
| PubMedID- 24564419 | infection with m. tuberculosis can lead to a variety of outcomes, which are generally different between children and adults, and this confirms the well known concept that “the child is not a small man”. |
| PubMedID- 26137541 | infection with mycobacterium tuberculosis (mtb) has an unpredictable outcome. |
| PubMedID- 24498451 | These investigations were undertaken because this species was noted to be highly susceptible to infection caused by members of the m. tuberculosis complex . |
| PubMedID- 25726678 | The results of study of adrenaline and noradrenaline concentration in urine in patients with pulmonary tuberculosis associated with hiv-infection are represented in the article. |
| PubMedID- 25699042 | In addition, lung infection with m. tuberculosis generates increased no expression levels, which negatively regulates the nlrp3-inflammasome, thereby decreasing il-1β production (85). |
| PubMedID- 24455461 | Double-knockout (ko) mice, deficient in both il-1α and il-1β, following infection with m. tuberculosis h37rv, have been reported to develop larger granulomatous lesions (yamada et al., 2000), whereas il-1 type 1 receptor knockout mice were highly susceptible, showed greater mycobacterial load, and developed granulomas with fewer mφs and lymphocytes, and abundant granulocytes (juffermans et al., 2000). |
| PubMedID- 21452902 | Global profiling was applied to characterize the responses of c57bl/6 mice to an aerobic infection with virulent mycobacterium tuberculosis (mtb). |
| PubMedID- 23077699 | Bronchopneumonia (27.5%) is the commonest pulmonary abnormality associated with hiv infection, while the prevalence of pulmonary tuberculosis is 5.88%. |
| PubMedID- 24712457 | Similarly, infection of mice with mycobacterium tuberculosis (mtb) was shown to trigger proliferation of pathogen-specific tcr-transgenic tregs 38. subsequent studies by the same group used tetramers to show that endogenous mtb-specific tregs also proliferated and expanded in the pulmonary lymph node of infected mice. |
| PubMedID- 22761866 | Six weeks after an aerosol infection with mycobacterium tuberculosis, c3heb/fej mice were split among four treatment groups: untreated (no treatment), standard tb treatment (rhz), etanercept alone and standard tb treatment with adjunctive etanercept (rhz + etanercept). |
| PubMedID- 24348997 | We conclude that the 5′ end of ncrv12659 provides a useful marker for phenotypic analysis of m. tuberculosis during infection with phirv2-positive strains, but that the distinctive transcriptional up-regulation of this locus in the starvation model is unlikely to play a direct role in the enhanced efficacy of the h56 vaccine against reactivation disease. |
| PubMedID- 21697069 | Atypical cutaneous mycobacteriosis co-infection with pulmonary tuberculosis in an immunocompetent patient. |
| PubMedID- 22384298 | The association of human immunodeficiency virus (hiv) infection with tuberculosis and tumours has been widely documented 7. |
| PubMedID- 23340041 | The infection with mycobacterium tuberculosis was confirmed by post-mortem and histological examinations of a female sub-adult elephant aged >12 years that died in tsavo east national park, kenya, while under treatment. |
| PubMedID- 26421237 | Following infection with m. tuberculosis, 5 to 10% of individuals go on to develop active tb within a short timeframe of one year (styblo, 1986). |
| PubMedID- 22901810 | During macrophage infection with mycobacterium tuberculosis, a vacuolar pathogen, exogenous induction of autophagy can limit replication, but the mechanism of autophagy targeting and its role in natural infection remain unclear. |
| PubMedID- 21977054 | The leaves and stem bark are used to treat diarrhea, kidney infection, heartburn, inflammation of the female organs, tuberculosis, general inflammation, and diabetes and was also used as an antiseptic . |
| PubMedID- 24677089 | High-frequency vaccine-induced cd8(+) t cells specific for an epitope naturally processed during infection with mycobacterium tuberculosis do not confer protection. |
| PubMedID- 20721576 | Despite our increasing knowledge, several key questions about latent infection and reactivation of m. tuberculosis remain unanswered. |