PedAM
Pediatric Disease Annotations & Medicines
| Disease | tuberculosis |
| Symptom | |infection |
| Sentences | 645 |
| PubMedID- 21703599 | Lysophospholipids may play an important protective role during primary infection of mycobacterium tuberculosis (mtb) by enhancing innate antimycobacterial immune response of both macrophages and alveolar epithelial cells. |
| PubMedID- 24039716 | The tuberculin skin test (tst) (of which the mantoux technique is most popularly employed) and interferon-gamma release assays (igras) are the most commonly used tools to diagnose infection with mycobacterium tuberculosis (m.tb) 2. |
| PubMedID- 24386296 | The release of interferon-gamma (ifn-γ) by t lymphocytes increases at a localized site of infection with mycobacterium tuberculosis antigen. |
| PubMedID- 21760796 | Importantly, whereas infection by avirulent forms of m. tuberculosis allows the host to repair these pm defects, virulent infection blocks this host repair process. |
| PubMedID- 23687908 | In various studies from africa, differing proportions of ocular tuberculosis in association with hiv infection have been reported, varying between 0 to 2.8%, depending on the size and clinical characteristic of the studied cohort . |
| PubMedID- 22319448 | However, taking into consideration that the reported esx-1-dependent type i interferon response to infection with m. tuberculosis occurs already 24 h post infection , it is plausible that rupture of the phagosomal membrane is preceded and/or initiated by pore-forming activity of esat-6, which might allow small signalling molecules such as cyclic diadenosine monophosphate (c-di-amp) or other pamps to translocate prior to the escape of entire bacteria and thereby trigger an early cytosolic host response. |
| PubMedID- 25814806 | Although dual infection with tuberculosis and bacteria/fungi has been reported in immunocompromised patients, their co-occurrence in individuals with preserved immunity may complicate the clinical presentation, leading to inadequate treatment and unsatisfactory outcomes. |
| PubMedID- 20808838 | This paper addressed the role of nlrp3 (nalp3), its adaptor protein pycard (asc), and caspase-1 during infection with mycobacterium tuberculosis (mtb). |
| PubMedID- 22280836 | The outcome of infection with mycobacterium tuberculosis (mtb) is determined by a complex and dynamic interaction between the host immune system and properties of the pathogen. |
| PubMedID- 26450607 | In addition, some patients have difficulties in understanding the nature of infection with tuberculosis which further hinders patients from adhering to their treatment once they are diagnosed and treatment is initiated.“migrants, they have very challenging socioeconomic situations. |
| PubMedID- 23056762 | So at the cut-off point of ≥15 mm among school children in this study, reaction is due to infection with mycobacterium tuberculosis but none of them developed active disease. |
| PubMedID- 22860031 | In the prevailing conditions of natural trap cave, the possibility of external post mortem infection with m. tuberculosis is most unlikely. |
| PubMedID- 23107218 | In clinical practice, latent infection with mycobacterium tuberculosis is defined by the presence of an m. |
| PubMedID- 24587128 | Background: co-infection with tuberculosis (tb) is the leading cause of death in hiv-infected individuals. |
| PubMedID- 24275361 | The latent infection is unique characteristic of mycobacterium tuberculosis to overcome human immune response for its survival. |
| PubMedID- 23575323 | Background: treatment of latent infection with mycobacterium tuberculosis effectively reduces future activation and transmission of tuberculosis. |
| PubMedID- 22216182 | The usual assumption is that upon infection with mycobacterium tuberculosis (mtb) for the first time, there is a chance that the individual will develop active tb disease within around 5 years –. |
| PubMedID- 21798463 | In the long term, vaccines that prevent or eradicate infection with mycobacterium tuberculosis would be the best possible option. |
| PubMedID- 20463815 | M. marinum established local infection with important features of human tuberculosis, including formation of granulomas with caseating centers. |
| PubMedID- 26344585 | Setting: the infection with mycobacterium tuberculosis gives a delayed immune response, measured by the tuberculine skin test. |
| PubMedID- 23580799 | Some studies proposed that infection with mycobacterium tuberculosis is acquired by direct contamination via peritoneal dialysate, whereas other researchers believe that infection is spread from another focus of tb in the body. |
| PubMedID- 25675653 | Historically, archaeological evidence, post-mortem findings and retrospective analysis of leprosy institutions' data demonstrates a high observed incidence of concomitant infection with leprosy and tuberculosis (tb). |
| PubMedID- 23717785 | The terminology used in the literature for children who demonstrate immunological evidence of infection with m tuberculosis, in the absence of clinical symptoms, is confusing. |
| PubMedID- 22844428 | It is estimated that worldwide over 2 billion individuals have latent infection with m. tuberculosis and almost 10 million new cases of active tuberculosis (tb) occur each year. |
| PubMedID- 20028811 | Herein, we investigate roles for fibrin(ogen) in an in vivo model of mycobacterial granuloma formation and in infection with mycobacterium tuberculosis, the causative agent of tuberculosis. |
| PubMedID- 24586159 | The role of tnf-α during infection with m. tuberculosis is complex. |
| PubMedID- 22771608 | (ii) fps (fresh/new tb cases pooled serum); patients who had infection with m. tuberculosis for the first time and had no history of tuberculosis treatment. |
| PubMedID- 26561839 | infection with mycobacterium tuberculosis should be considered in all patients who present symptoms suggesting tuberculosis, have had recent contact with a person suffering from lung tuberculosis or are planned to undergo an immunosuppressive treatment. |
| PubMedID- 23278987 | The importance of chemoprophylaxis should be emphasized to minimize the risk of developing active tuberculosis in patients with latent tuberculosis infection undergoing solid organ transplantation. |
| PubMedID- 24916152 | infection of humans with mycobacterium tuberculosis remains frequent and may still lead to death. |
| PubMedID- 21364878 | Animal ethics approval for mouse infection with m. tuberculosis was obtained from the institutional animal care and use committee at the public health research institute center of university of medicine & dentistry, new jersey (umdnj). |
| PubMedID- 23671837 | A high degree of strain homogeneity and previous infection with m. tuberculosis raises the question of whether large-scale testing and treatment of latent infection might be an effective way of dramatically reducing tb rates in some of the isolated communities in the nwt. |
| PubMedID- 21876616 | tuberculosis, crohn's disease) result from infection (abscess) in anal glands extending from the intersphincteric plane to various anorectal spaces. |
| PubMedID- 22762692 | The tuberculin skin test, which involves monitoring the immune reaction to an injection of purified protein derivative (ppd), has been the most widely used method for detecting infection with mycobacterium tuberculosis since its development in 1930s. |
| PubMedID- 23323174 | A spinal infection with tuberculosis may be associated with a pulmonary infection, which occurs in less than 1% of patients with tuberculosis or, more rarely, the condition may be encountered in the absence of a pulmonary infection8). |
| PubMedID- 20304601 | Incision infection with mycobacterium tuberculosis after total hip arthroplasty without any primary tuberculosis focus. |
| PubMedID- 26132135 | infection of macrophages with virulent m. tuberculosis decreased annexin v levels (fig 7a) along with a concomitant decrease in aif levels and an increase in bcl2 levels (fig 7b). |
| PubMedID- 25097193 | Children were screened for infection with m tuberculosis with interferon gamma release assays. |
| PubMedID- 20596522 | For example, neutrophils played a protective role at the early phase of infection with m. tuberculosis in one study; where neutrophil depletion significantly compromised host defense . |
| PubMedID- 26108288 | Il-17 production has been implicated in the induction and maintenance of the th1 response following bcg vaccination and recruitment of cells to the lung following infection with m. tuberculosis (28, 29) and correlates with improved outcome following m. tuberculosis exposure in nonhuman primates (nhp) (30). |
| PubMedID- 25246930 | It is believed that the fallopian tubes are the commonest site for genital infection constituting about 94.7% of cases of genital tuberculosis (24). |
| PubMedID- 21731497 | The second one contains 359 genes and corresponds to irf8 targets (bound by irf8) that are regulated during pulmonary infection with m. tuberculosis in vivo. |
| PubMedID- 22147526 | infection with mycobacterium tuberculosis (mtb) remains a major global health threat, with over nine million new cases and close to two million deaths annually. |
| PubMedID- 22771605 | However, a positive tst only indicates infection with m. tuberculosis and does not always indicate active disease. |
| PubMedID- 22567268 | These findings suggest that bcg is unlikely to be effective in preventing infection with m. tuberculosis but may prevent progression of infection to disease, particularly disseminated forms of tb disease. |
| PubMedID- 23238684 | The purpose of this study was to evaluate the cost-effectiveness of the strategy of controlling the contacts of tuberculosis patients with latent tuberculosis infection by means of treatment with rifampin for 4 months or isoniazid for 9 months. |
| PubMedID- 24804006 | The well-known work on pathologic anatomy by robbins and cotran emphasises that it is important to differentiate between infection with m. tuberculosis and the full-blown disease.22 infection is defined as the presence of microorganisms that may or may not cause clinically significant tissue damage (i.e., the disease). |
| PubMedID- 23209384 | Furthermore, new technologies such as sputum pcr are available for rapid molecular diagnosis of infection with mycobacterium tuberculosis, but it is unclear if these technologies are cost-effective for use in highly endemic prisons. |
| PubMedID- 23970967 | Mycobacterial etiology of pulmonary tuberculosis and association with hiv infection and multidrug resistance in northern nigeria. |
| PubMedID- 22919654 | Moreover, one gene regulated by csor, the cu transporter ctpv gene, was also shown to impact the survival of animals following aerosol infection with m. tuberculosis (ward et al., 2008), another indication of the importance of biometals to the pathogenesis of tuberculosis. |