PedAM
Pediatric Disease Annotations & Medicines
| Disease | tuberculosis |
| Symptom | |infection |
| Sentences | 645 |
| PubMedID- 21029662 | Exclusive criteria included infection with tuberculosis and hepatitis b etc., abnormal renal or hepatic function. |
| PubMedID- 22911807 | Thus, host genetic susceptibility, combined with environmental factors, may play a crucial role in exploring the infection mechanism of mycobacterium tuberculosis . |
| PubMedID- 20613858 | Control of infection with mycobacterium tuberculosis (mtb) requires th1-type immunity, of which cd8+ t cells play a unique role. |
| PubMedID- 23559818 | Bronchitis, sinusitis, pneumonia caused by encapsulated bacteria like haemophilus influenzae, streptococcus pneumonia, etc., have been seen as well as infection with mycobacterium tuberculosis can develop early in the course of disease. |
| PubMedID- 23579317 | In the mice model, cd4+ t cell responses in old age during infection with m. tuberculosis are declined when compared young mice23. |
| PubMedID- 23857684 | Comorbidity of pulmonary tuberculosis with alcoholism, hiv infection, and dm was identified in 15.0%, 4.5%, and 3.2% of the cases, respectively. |
| PubMedID- 26106603 | Some evidences exist about a high risk of developing active tuberculosis (tb) in patients with latent tb infection undergoing anti-tnf-α therapy as well as the development of ntm disease during this therapy . |
| PubMedID- 26129756 | However, only infection with tuberculosis (adjacent hr ahr: 5.3; 95% ci, 1.6–17.8; p < .01) and art initiation status maintained statistical significance through the forward step-wise approach and were therefore retained in the final multivariable model for mortality (table 4). |
| PubMedID- 26064970 | Therefore, the granuloma macrophages could control bcg infection in mice with latent tuberculosis in vivo and in the ex vivo culture. |
| PubMedID- 22132068 | Wt (black circles), tnf−/− (white diamonds) and tm-tnf (white squares) mice were exposed by aerosol inhalation infection to 100–200 cfus/mouse of m. tuberculosis h37rv for 3 weeks preceding chemotherapy with 25 mg/kg inh-rif for 6 weeks in drinking water. |
| PubMedID- 20039878 | Granuloma formation represents a pivotal point during human infection with mycobacterium tuberculosis, for this structure may limit mycobacterial spread and prevent active disease, while at the same time allow for the survival and persistence of viable mycobacteria within the host. |
| PubMedID- 20522497 | Thus, a defect during early growth in lungs specifically at week 1 and increased inflammation were the hallmarks of acute infection with the m. tuberculosis δpknk strain. |
| PubMedID- 25583311 | An additional opportunistic infection with multiresistant pulmonary tuberculosis was diagnosed. |
| PubMedID- 22583610 | Objective: to determine the prevalence and trend of drug resistance and human immunodeficiency virus (hiv) co-infection among children with culture-confirmed tuberculosis (tb). |
| PubMedID- 20559431 | Mice were exposed to a low-dose aerosol infection (lda) with m. tuberculosis strain erdman (tmcc 107) in a glass-col inhalation exposure system (glas-col inc., terre haute, indiana) as previously described . |
| PubMedID- 26060998 | The diversity of gut microbiota has been shown to decrease in a mouse model following infection with m. tuberculosis . |
| PubMedID- 21933877 | Methods: in an attempt to identify the mechanisms underlying the superior protection of rbcg, we compared the immune responses elicited after vaccination and subsequent aerosol infection with mycobacterium tuberculosis (mtb) in mice. |
| PubMedID- 21731675 | The immunosuppression induced by hiv infection increases the risk of developing tuberculosis 7. |
| PubMedID- 22649518 | Given that ido-1 deficiency enhanced mycobacteria-specific t cell proliferation in vitro we examined the influence of ido-1 on the generation of an antigen-specific t cell response following infection with m. tuberculosis in vivo. |
| PubMedID- 25703567 | By comparing outbred rabbits (which are intrinsically resistant to infection with mycobacterium tuberculosis) and inbred rabbits that showed enhanced susceptibility to infection, they proposed that tuberculosis disease could be classified into five stages: (i) the ingestion of bacilli by pulmonary alveolar macrophages; (ii) bacterial growth in non-activated macrophages recruited from blood circulation; (iii) the arrest of bacterial growth by delayed-type hypersensitivity (dth) causing the initiation of formation of solid caseous lesions; (iv) the onset of cell-mediated immunity that is thought to stabilize caseous lesions; and (v) liquefaction of the caseous center, with extracellular bacterial growth and cavity formation. |
| PubMedID- 22589721 | It has been proposed that the increase in m. tuberculosis pathology associated with hiv infection is caused by the disruption of the local immune response within the tuberculosis granulomas, decreasing their ability to contain m. tuberculosis leading to increased mycobacterial replication, dissemination and clinical disease . |
| PubMedID- 24625963 | In the present study, we have also shown that infection of macrophages with heat-killed m. tuberculosis (h37rv) led to up-regulation of fam46a rna while a previous report also showed up-regulation of bag6 rna in macrophages upon stimulation with esat protein of m. tuberculosis. |
| PubMedID- 21396127 | Following histopathological confirmation of the postoperative sample as chronic granulomatous infection due to tuberculosis, he sustained significant clinical improvement with antituberculous therapy, recovered fully and was discharged at two weeks post-treatment. |
| PubMedID- 25763458 | Rationale: latent infection with mycobacterium tuberculosis is defined by a positive ifn-gamma release assay (igra) result in the absence of active tuberculosis. |
| PubMedID- 23316226 | Patients with hiv infection have higher risk of extrapulmonary tuberculosis, tuberculosis relapse, and death than non-hiv-infected patients 4. |
| PubMedID- 21375756 | infection with mycobacterium tuberculosis (m. |
| PubMedID- 26142701 | For instance, during infection with mycobacterium tuberculosis (mtb), processing of infected apoptotic cells by macrophages enhances anti-bacterial innate and adaptive immune responses. |
| PubMedID- 24807690 | Furthermore, usp18ity9 mice are more susceptible to infection with mycobacterium tuberculosis, have increased bacterial load in lung and spleen, elevated inflammatory cytokines and more severe lung pathology. |
| PubMedID- 24352433 | In december 2012, the united states food and drug administration (fda) granted accelerated approval of bedaquiline, a diarylquinoline antimycobacterial drug, for the treatment of mdr-tb (infection with m. tuberculosis resistant to rifampin and isoniazid), including xdr-tb (resistance to rifampin, isoniazid, a quinolone and one of the injectable drugs: kanamycin, amikacin or capreomycin), when no other treatment options exist2. |
| PubMedID- 25950182 | Pulmonary infection with m. tuberculosis h37rv was performed by instillation of 1000–3000 cfu/lung into the nasal cavities (20μl each) under xylazine-ketamine anaesthesia (100mg/kg ketamine, 10mg/kg xylazine, i.p. |
| PubMedID- 21762531 | We have previously demonstrated that p27-p55 (lprg-rv1410c) operon . |
| PubMedID- 20936108 | This immense burden of disease is fuelled by very high rates of infection with mycobacterium tuberculosis, estimated to occur in approximately one third of the world's population 3. |
| PubMedID- 22952596 | infection and transmission of multidrug-resistant mycobacterium tuberculosis (mdr-mtb) and extensively drug-resistant m. |
| PubMedID- 22624142 | All of the patients had at least one antecedent pulmonary abnormality including a history of infection with tuberculosis, pulmonary malignancy, chronic bronchitis and smoking. |
| PubMedID- 22114556 | (b) lung sections of wildtype (wt) mice demonstrating formation of compact, well-circumscribed tuberculous lesions after four weeks infection with m. tuberculosis (i). |
| PubMedID- 21521247 | Furthermore, dcs from mmr knockout mice secrete more il-12p40 upon infection with m. tuberculosis as compared with dcs from wild-type mice (ehlers, 2009). |
| PubMedID- 23825603 | infection with m. tuberculosis that was attributed to poor cd4+ t cell responses , . |
| PubMedID- 22039457 | Cell supernatant cytokines released by the j774a.1 macrophage at the different time-points post-infection with the m. tuberculosis h37rv strain or the m. tuberculosis δ-mce1-h37rv strain. |
| PubMedID- 23024786 | This study focuses on lr aggregation induced in alveolar epithelial cells during infection with mycobacterium tuberculosis (mtb) bacilli. |
| PubMedID- 25655663 | This study examines predictors of smoking cessation in tuberculosis patients with high hiv co-infection rates in a south african primary care setting. |
| PubMedID- 21572609 | The outcome of infection with m. tuberculosis varies from person to person, some people develop active disease in either short periods (primary tuberculosis) or long periods (reactivation), and some are able to control infection and settle into a latent state. |
| PubMedID- 26335136 | Important clinical data collected included baseline and serial assessments of cd4+ t-cell counts (every six months) and plasma hiv-1 rna viral load (once or twice yearly), follow-up duration, history of cart prescription and co-infection with either tuberculosis or hepatitis b/c (hbv/hcv). |
| PubMedID- 26200971 | This case illustrates that infection with tuberculosis might impair the host's immune system and increase the risk of invasive candidiasis in an immunocompetent patient. |
| PubMedID- 23181236 | Hiv infection increases the risk of developing active tuberculosis by 15–30 times. |
| PubMedID- 21999773 | Like all other infectious diseases, the primary event determining the disease epidemiology is the acquisition of infection with mycobacterium tuberculosis by a susceptible individual. |
| PubMedID- 22233936 | Conclusions: prosthetic joint infection with mycobacterium tuberculosis is uncommon. |
| PubMedID- 21083879 | Anti-tnf agents have a substantial risk of infection with mycobacterium tuberculosis . |
| PubMedID- 26175730 | Natural human infection with m. tuberculosis most often occurs after inhalation of infectious aerosols and yet another group of investigators have demonstrated that macaques infected by the head-only aerosol route develop disease that appears to be very similar to human tb. |
| PubMedID- 24660085 | On the other hand, serious opportunistic infection and reactivation of pathogens, such as tuberculosis, pneumocystis jiroveci, hepatitis b virus (hbv), cytomegalovirus (cmv), epstein-barr virus (ebv), and human immunodeficiency virus, have been reported to be associated with ifx treatment . |
| PubMedID- 21318182 | B cells are thus likely to be more important in determining the outcome of infection with m. tuberculosis than previously supposed, and ignoring this aspect of the host immune response may restrict our understanding of tb immunopathology. |