PedAM
Pediatric Disease Annotations & Medicines
| Disease | hyperglycemia |
| Phenotype | |diabetes |
| Sentences | 383 |
| PubMedID- 24387617 | An early work reveals that hyperglycemia in diabetes triggers nutrient excess in neurons, that mediates the phenotype changes in mitochondria, and the development of axon loss in sensory neuropathy is linked to this nutrient excess [26,27]. |
| PubMedID- 21521130 | Introduction: in preliminary clinical studies, aleglitazar, a new dual ppar-alpha-gamma agonist, has been demonstrated to improve hyperglycemia and dyslipidemia in patients with type 2 diabetes mellitus. |
| PubMedID- 23351522 | Therefore, to avoid the potential risk of ketoacidosis precipitated by olanzapine-associated hyperglycemia, persons with type i diabetes are excluded from the study. |
| PubMedID- 26126619 | In contrast to injection of stz to adult rats in a lower dose (60 mg/kg) that leads to type 1 diabetes with severe hyperglycemia [14, 24–27], administration of stz to neonatal rats in a higher dose (90–100 mg/kg) leads to acute hyperglycemia within the first few days without resulting in complete loss of insulin production [14, 24–27]. |
| PubMedID- 23435159 | Inpatient hyperglycemia in patients, with or without diabetes, is associated with poor hospital outcomes, including prolonged hospital stay, infections, and disability after hospital discharge, and death (1–3). |
| PubMedID- 25562721 | Cedrela odorata is effective in diminishing glucose levels in vitro and in vivo and in ameliorating oxidative damage that occurs in diabetes and/or due to hyperglycemia in rats. |
| PubMedID- 23791753 | Chronic hyperglycemia in diabetes is associated with oxidative stress mediated tissue damage. |
| PubMedID- 24381887 | Since it often has a long asymptomatic period of hyperglycemia, many individuals with type-2 diabetes have complications at the time of diagnosis, neuropathy being most frequent. |
| PubMedID- 21220752 | Conclusion: we conclude that hyperglycemia in diabetes, independent of plasma aldosterone concentration, induces podocyte injury through mr-mediated ros production and leads to proteinuria. |
| PubMedID- 21931813 | Also increasing in incidence is type ii diabetes mellitus (t2d), associated with hyperglycemia, insulin-resistance, and hyperlipidemia [3], [6], [7]. |
| PubMedID- 24757043 | In our obese and overweight population, three patients have impaired glucose tolerance, one has cf-related diabetes (cfrd) with fasting hyperglycemia, three have hypertension, and one has obstructive sleep apnea (osa). |
| PubMedID- 22086363 | In the surgical population, hyperglycemia with or without diabetes mellitus may be unrecognized. |
| PubMedID- 24807533 | Transient carotid artery occlusion causes ischemia/reperfusion (i/r) injury resulting in neuron and pancreatic beta-cell death with consequential post-stroke hyperglycemia, which can lead to diabetes and may accelerate the development of alzheimer's disease. |
| PubMedID- 25922827 | The increase in the cu2+ levels in patients with diabetes might be attributed to hyperglycemia that may stimulate glycation and release of cu2+ from copper-containing enzymes. |
| PubMedID- 24532508 | Our results indicated that we were able to induce hyperglycemia with type 2 diabetes and establish a chronic stress model in mice. |
| PubMedID- 22187476 | Unexplained hyperglycemia in a patient with type 1 diabetes may suggest impending dka, and monitoring of ketones should therefore be performed. |
| PubMedID- 22142413 | Furthermore, the formation of ages may play a key role in diabetes and cvd, leading to chronic hyperglycemia, dyslipidemia and oxidative stress [5]. |
| PubMedID- 25317173 | Early macrovascular atherosclerosis may play a crucial role in subtle brain atrophy in type 2 diabetes mellitus patients, with chronic hyperglycemia playing a lesser role. |
| PubMedID- 21046527 | Aleglitazar, being developed by roche holding, is a dual agonist for ppargamma and pparalpha for the potential simultaneous treatment of hyperglycemia and dyslipidemia in patients with type 2 diabetes mellitus (t2dm). |
| PubMedID- 26453314 | However, hif-1 signaling is inhibited in diabetes due to hyperglycemia-induced hif-1alpha destabilization and functional repression. |
| PubMedID- 20959527 | Atrial natriuretic peptide (anp) levels correlate with hyperglycemia in diabetes mellitus, but anp effects on pancreatic islet beta-cell insulin secretion are controversial. |
| PubMedID- 24486986 | hyperglycemia in diabetes results in the glycation of long-lived proteins. |
| PubMedID- 24895642 | Diabetic retinopathy is a microvascular complication of diabetes correlated with chronic hyperglycemia [1]. |
| PubMedID- 21617178 | Because of a mutation in the leptin receptor, bks db/db mice are hyperphagic and obese, develop severe type 2 diabetes with marked hyperglycemia, and serve as an experimental model of type 2 diabetes. |
| PubMedID- 21838680 | The increased oxidative stress in subjects with type 2 diabetes is a consequence of several abnormalities, including hyperglycemia, insulin resistance, hyperinsulinemia, and dyslipidemia, each of which contributes to mitochondrial superoxide overproduction in endothelial cells of large and small vessels as well as the myocardium. |
| PubMedID- 24967064 | Chronic hyperglycemia in diabetes stimulates reactive oxygen species (ros) production with development of microangiopathic complications such as diabetic retinopathy (dr) and diabetic nephropathy (dn) (1). |
| PubMedID- 20425572 | hyperglycemia occurs in patients with diabetes and in nondiabetic patients during acute illness. |
| PubMedID- 22923476 | The subsequent hyperglycemia in diabetes is the foremost risk factor for vascular complications due to enhanced rates of cellular apoptosis as observed in retinal pericytes, renal podocytes, and vascular endothelial cells (3,4). |
| PubMedID- 25705228 | To prevent worsening hyperglycemia with underlying diabetes mellitus, steroids were avoided and the patient was started on an immunosuppressant, azathioprine. |
| PubMedID- 23610083 | A girl (now 17 years old; bmi, 20.1 kg/m2) had diabetes presenting with moderate hyperglycemia without dka diagnosed at the age of 4 years. |
| PubMedID- 21115768 | Subjects who had at least one ogtt performed during the study period were identified as having normal glucose tolerance (ngt), igt, cystic fibrosis–related diabetes without fasting hyperglycemia (cfrd fh−) or cfrd with fasting hyperglycemia (cfrd fh+) by standard definitions (table 1). |
| PubMedID- 25729706 | The response of α-cell to hyperglycemia in diabetes is blunted or vanishing, and plasma glucagon remains inappropriately excessive at comparable blood glucose levels. |
| PubMedID- 23319980 | It has been shown that serum vap-1 is elevated in acute and chronic hyperglycemia and in patients with diabetes [7]. |