PedAM
Pediatric Disease Annotations & Medicines
| Disease | hyperglycemia |
| Phenotype | |diabetes |
| Sentences | 383 |
| PubMedID- 23209929 | It has also been suggested that chronic exposure to hyperglycemia and hyperinsulinemia, in patients with type 2 diabetes, could contribute to the proliferation of hepatic stem cells, at higher risk for malignant transformation [10]. |
| PubMedID- 26345606 | Persistent hyperglycemia in patients with diabetes mellitus is said to be associated with various complications. |
| PubMedID- 21525446 | diabetes is associated with hyperglycemia-specific microvascular complications. |
| PubMedID- 25284699 | Glucagon-like peptide-1 receptor (glp-1) agonists and dipeptidyl-peptidase-4 (dpp-4) inhibitors are therapies that are used to treat hyperglycemia in patients with type 2 diabetes mellitus. |
| PubMedID- 24194733 | In diabetes, reduction of endothelial no-levels, systemic hyperglycemia if uncontrolled, generation of reactive oxygen species, oxidative stress, and increased ldl-oxidation, formation of ages, and increased circulating free fatty acids are factors that add to atherosclerosis and cvd risk. |
| PubMedID- 24324393 | While frank autonomic neuropathy almost certainly contributes to the altered vagal sensory and motor functions observed in chronic diabetes, the actions of acute hyperglycemia to modulate vagal afferent and efferent functions (macgregor et al., 1976; shi et al., 2003; takahashi et al., 2003; zhou et al., 2008) suggests that poor glycemic control per se also negatively impacts vagal reflex functions. |
| PubMedID- 22911800 | hyperglycemia in diabetes mellitus damages blood vessels and induces vascular complications in the retinal, renal, and cardiovascular tissues [1], [2]. |
| PubMedID- 21115766 | We hypothesized that postbreakfast hyperglycemia in subjects with type 2 diabetes could be improved nonpharmacologically by using a high-protein, low-carbohydrate prebreakfast snack. |
| PubMedID- 26171401 | However, whether the use of exogenous insulin (i.e., human insulin or insulin analogues) for treating hyperglycemia in patients with diabetes actually increases the risk of breast cancer is the subject of recent debate [18–20]. |
| PubMedID- 20103560 | Recent trials on the prevention of cvd events by the treatment of hyperglycemia in patients with type 2 diabetes have been disappointing. |
| PubMedID- 25756053 | We conclude that hyperglycemia, which results from maternal diabetes and precedes embryo implantation, deregulates the intrauterine developmental timeline, restricts embryo-fetal growth, and primarily delays the remodeling and maturation of the structures derived from neural crest cells. |
| PubMedID- 22128218 | It has been shown that the hyperglycemia associated with diabetes mellitus results in the activation of neutrophils(51) and that this activation contributes to an increase in oxidative stress that is partly responsible for diabetes complications. |
| PubMedID- 21172030 | Agents that modulate bile acids may potentially affect both cholesterol and glucose metabolism, and hence dyslipidemia and hyperglycemia, in patients with type 2 diabetes [69,71,72]. |
| PubMedID- 24716195 | An increase of cardiovascular diseases due in part to hyperglycemia is associated with diabetes, which can induce endothelial dysfunction [2]. |
| PubMedID- 22296854 | Conclusions: the present results provide first evidence indicating that ems is a new exercise method for treating postprandial hyperglycemia in individuals with type 2 diabetes, especially who cannot perform adequate voluntary exercise because of excessive obesity, orthopedic diseases, or severe diabetic complications. |
| PubMedID- 24864247 | hyperglycemia in diabetes can cause up to a 4-fold increase in neuronal glucose levels. |
| PubMedID- 23166623 | Type 2 diabetes (t2d) is associated with dyslipidemia, hyperglycemia, insulin resistance, and defects in insulin secretion from pancreatic beta cells [1]. |
| PubMedID- 24067431 | Dapagliflozin, a sodium-glucose cotransporter-2 inhibitor, reduces hyperglycemia in patients with diabetes and normal or mildly impaired renal function. |
| PubMedID- 23557386 | Conclusions: high-dose prednisone for 2 to 3 months produced an elevated incidence of diabetes, usually with mild hyperglycemia occurring between the second and fourth week, normalizing spontaneously in all cases. |
| PubMedID- 21282368 | Recently, we have shown that serum vap-1 is elevated in acute and chronic hyperglycemia and in patients with diabetes (13). |
| PubMedID- 24717767 | Abnormal regulation of glucagon secretion has been implicated in the development of hyperglycemia in patients with type 2 diabetes mellitus [16], and a recent study in animal models indicated that a reduction in glucagon action can have profound effects on mitigating hyperglycemia even in the presence of severe hypoinsulinemia [17]. |
| PubMedID- 23915015 | Background: depression is common in diabetes and associated with hyperglycemia, diabetes related complications and mortality. |
| PubMedID- 22361035 | Chronic hyperglycemia in diabetes leads to free radicals overproduction, which contributes to the development of diabetic nephropathy. |
| PubMedID- 21912542 | Here, we detail the strategies that our institutions have employed to identify and treat hyperglycemia in patients with diabetes who present for surgery. |
| PubMedID- 26084668 | However, the optimal treatment of hyperglycemia in patients with diabetes to reduce the progression of hf has not been well studied. |
| PubMedID- 21039714 | hyperglycemia associated with diabetes was pronounced after excision of the tumor and had been masked by the paraneoplastic effect of the tumor. |
| PubMedID- 23250800 | Our aim was to determine if increased nitric oxide generation by l-arginine infusion would reverse this deleterious response to clamped hyperglycemia in women with type 1 diabetes mellitus. |
| PubMedID- 23452437 | These results suggest that the progression of atherosclerosis might be directly dependent upon hyperglycemia in patients with established diabetes status [15,16] but might be influenced by multiple cv risk factors, especially the component of increased blood pressure [17], in patients with a status of ms without diabetes. |
| PubMedID- 23799024 | The vascular complications in diabetes are causally associated with hyperglycemia-induced ros overproduction and a large body of evidence has suggested that endothelial dysfunction is caused by ros [22]. |
| PubMedID- 24089511 | Glp-1 agonists have been incorporated into standard algorithms to treat hyperglycemia in patients with type 2 diabetes, and while the objective of these treatment regimens is to reduce glycemia safely (2), the importance of specifically targeting postprandial glycemia is increasingly being recognized (3). |
| PubMedID- 25935773 | The clinical management of hyperglycemia in pregnancy complicated by maturity-onset diabetes of the young. |
| PubMedID- 24516103 | Dipeptidyl peptidase-4 inhibitors prevent the degradation of incretin hormones and reduce postprandial hyperglycemia in patients with type 2 diabetes mellitus. |
| PubMedID- 21464443 | Leptin therapy reverses hyperglycemia in mice with streptozotocin-induced diabetes, independent of hepatic leptin signaling. |
| PubMedID- 20876838 | Managing hyperglycemia in patients with type 2 diabetes mellitus: rationale for the use of dipeptidyl peptidase-4 inhibitors in combination with other oral antidiabetic drugs. |
| PubMedID- 22187370 | Type 1 diabetes presents clinically with overt hyperglycemia resulting from progressive immune-mediated destruction of pancreatic beta-cells and associated metabolic dysfunction. |
| PubMedID- 24224091 | Several factors such as dyslipidemia or hyperlipidemia which are involved in the microvascular and macrovascular complications as well as hyperglycemia are associated with the diabetes disease which is the major cause of morbidity and death [4]. |
| PubMedID- 23267675 | Twenty-two technical knowledge questions involved such concepts as the target age for diabetes testing, the benefits of exercise, hyperglycemia, groupings of foods and their exchange list, ideal body weight, and ketoacidosis. |
| PubMedID- 22196774 | His laboratory blood values showed a non-regulated diabetes mellitus with hyperglycemia of 32 mmol/l, white blood cell count of 18 × 109/l with 81.6% polymorphonuclear cells (pmns), elevated c-reactive protein (crp), hemoglobin, sodium and creatinine. |
| PubMedID- 23087670 | Persistent hyperglycemia in patients with diabetes may activate another lipogenic transcription factor, carbohydrate response element binding protein (chrebp; iizuka et al., 2004; dentin et al., 2006; ma et al., 2006; postic et al., 2007; davies et al., 2008). |
| PubMedID- 21386984 | hyperglycemia in diabetes can cause up to four-fold increases in neuronal glucose levels. |
| PubMedID- 21115767 | Type 1 diabetes leads to hyperglycemia, which is linked to a number of acute (e.g., diabetic ketoacidosis) and chronic (e.g., diabetic nephropathy and cardiovascular disease) complications (1). |
| PubMedID- 26398746 | Nevertheless, the long-term consequence of elevated pkc-phosphorylation/activity should be considered in diabetes with chronic hyperglycemia [16]. |
| PubMedID- 26317347 | Agonist-induced activation of pparγ has been demonstrated to increase insulin sensitivity [25, 26] and thiazolidinediones (tzd) are used clinically to reduce insulin resistance and hyperglycemia in patients with type 2 diabetes, although these drugs are also associated with weight gain [27–31]. |
| PubMedID- 22580727 | The pathogenesis of nafld remains obscure, but it has been hypothesized that hepatic fat accumulation in type 1 diabetes may be due to lipoprotein abnormalities, hyperglycemia-induced activation of the transcription factors carbohydrate response element-binding protein (chrebp) and sterol regulatory element-binding protein 1c (srebp-1c), upregulation of glucose transporter 2 (glut2) with subsequent intrahepatic fat synthesis, or a combination of these mechanisms. |
| PubMedID- 24990094 | The relationship between hyperglycemia (including diabetes) and periodontal disease (pd) has been noted previously, but its temporal sequence in the same study based on a population-based study has been barely addressed. |
| PubMedID- 23690866 | In addition, high fructose consumption progresses to dietary model of type 2 diabetes that is associated with obesity, ir, hyperglycemia, and dyslipidemia [2]. |
| PubMedID- 20413513 | The 11-beta-hydroxysteroid dehydrogenase type 1 inhibitor incb13739 improves hyperglycemia in patients with type 2 diabetes inadequately controlled by metformin monotherapy. |
| PubMedID- 24404519 | While many studies have reported that psychiatric stress aggravates hyperglycemia in diabetes [3], the pattern and extent of hyperglycemia induced by psychiatric stress and the difference in the amount of psychiatric stress-induced hyperglycemia between normal and diabetic subjects remain unknown. |
| PubMedID- 24671257 | Moreover, the occurrence of peri-implantitis, bacteremia, or hyperglycemia in individuals with diabetes may be long-lasting; however, our electrochemical tests were carried out over the short term. |
| PubMedID- 22178606 | In the latter, the process is further aggravated by hyperglycemia, leading to diabetes complications of cns. |