PedAM
Pediatric Disease Annotations & Medicines
| Disease | hyperglycemia |
| Symptom | C0011847|diabetes |
| Sentences | 382 |
| PubMedID- 21217061 | hyperglycemia in diabetes mellitus promotes oxidative stress in endothelial cells, which contributes to development of cardiovascular diseases. |
| PubMedID- 21502328 | Results: fifteen percent of cf patients had glucose intolerance and 6% had diabetes without fasting hyperglycemia and 3% had diabetes with fasting hyperglycemia. |
| PubMedID- 21772974 | Uncontrolled diabetes with hyperglycemia has been suggested as a possible mechanism for osteoporosis in both type 1 and type 2. this can occur by the formation of nonenzymatic glycosylation of various bone proteins, including type 1 collagen, leading to impaired bone quality . |
| PubMedID- 26340671 | Moreover, the function of bm stem cells may be affected by hyperglycemia associated with diabetes 7. |
| PubMedID- 21394317 | Steroid is associated with the risk of hyperglycemia in patients with or without diabetes (10, 11). |
| PubMedID- 26587047 | Nevertheless, in a randomized, blinded, crossover study, a single oral dose of quercetin (400 mg) effectively suppressed postprandial hyperglycemia in patients with type 2 diabetes . |
| PubMedID- 23576884 | Background: the purpose of this paper is to review the efficacy, safety, and tolerability of linagliptin in the management of hyperglycemia in adults with type 2 diabetes mellitus. |
| PubMedID- 21715522 | However, postprandial glucose may contribute less to overall glycemic control than preprandial glucose in patients with diabetes, and the role of postprandial hyperglycemia as an independent cardiovascular risk factor is still uncertain (22). |
| PubMedID- 21193621 | A subsequent study further demonstrated that diabetes distress covaried with hyperglycemia over time, but depressive symptoms and mdd did not (7). |
| PubMedID- 23319980 | It has been shown that serum vap-1 is elevated in acute and chronic hyperglycemia and in patients with diabetes 7. |
| PubMedID- 24734255 | Besides chronic hyperlipidemia and hyperglycemia, patients with diabetes display an increased ratio of oxidized ldl over native ldl . |
| PubMedID- 20028938 | From a fasting ffa of 0.4 ± 0.3 mmol/l in diabetic subjects and 0.4 ± 0.3 mmol/l in control subjects, ffa levels increased to 1.5 ± 1.1 mmol/l in kpdm, 1.9 ± 0.4 mmol/l in obese type 2 diabetes with hyperglycemia, and 1.8 ± 1.1 mmol/l in nondiabetic control subjects at the end of intralipid infusion, respectively (p = ns difference between groups at baseline or during intralipid infusion). |
| PubMedID- 21410975 | Exenatide twice daily (exenatide bid) was the first glp-1 receptor agonist approved for treatment of hyperglycemia in patients with type 2 diabetes not adequately controlled with diet and exercise, sulfonylurea (sfu), tzd, or metformin (met; alone, or with an sfu, or tzd). |
| PubMedID- 20587056 | hyperglycemia associated with type 1 diabetes can activate nf-κb , which is known to induce b1r . |
| PubMedID- 21886908 | The purpose of the current study was to assess whether type 2 diabetes mellitus-induced hyperglycemia has an effect on the lipid profile and release of oxidative stress markers and inflammatory mediators in patients with non alcoholic fatty liver disease and normal liver function tests which may in turn lead to enhancing the pathogenicity of this liver disease. |
| PubMedID- 24947195 | Mononuclear invasion of langerhans islet and the ensuing insulitis triggers signal-transduction for the autoimmune mediated pancreatic beta-cell (beta-cell) apoptosis that severely disrupts insulin production resulting in hyperglycemia associated with type-1 diabetes (t1dm). |
| PubMedID- 21357363 | Since 1995 there have been multiple new drugs approved by the food and drug administration for the treatment of hyperglycemia in patients with type 2 diabetes, including the biguanide metformin, α-glucosidase inhibitors, thiazolidinediones, glinides, glp-1 analogs, amylin analogs, dipeptidyl peptidase-iv inhibitors (31), a bile acid sequestrant (32), and most recently a dopamine receptor agonist (33). |
| PubMedID- 22745639 | It is well known that diabetes is associated with hyperglycemia, elevated oxidative and carbonyl stress, and low tissue and plasma levels of gsh , conditions that complicate the diabetic state, which would lead to further exacerbation of gsh loss. |
| PubMedID- 23890278 | Stress-induced diabetes, with hyperglycemia and ir, during acute hospitalization is a hallmark of severely burned patients and a common pathophysiological phenomenon 4. |
| PubMedID- 23250800 | Our aim was to determine if increased nitric oxide generation by l-arginine infusion would reverse this deleterious response to clamped hyperglycemia in women with type 1 diabetes mellitus. |
| PubMedID- 25995968 | On the basis of all the research articles used for this review, it is reasonable to propose that naw may offer a potent and complete oral therapy for treatment of t2d patients, and also for those patients who have higher risk of developing diabetes due to overweight, hyperglycemia, and hypertension. |
| PubMedID- 23346258 | In the absence of insulin, glucose uptake from peripheral tissues is inhibited; thus hyperglycemia occurs, leading to diabetes, and fat becomes the energy source of the organism via gluconeogenesis . |
| PubMedID- 23557386 | Conclusions: high-dose prednisone for 2 to 3 months produced an elevated incidence of diabetes, usually with mild hyperglycemia occurring between the second and fourth week, normalizing spontaneously in all cases. |
| PubMedID- 25918533 | A 30-year-old obese male patient had been diagnosed with diabetes mellitus due to acute hyperglycemia and ketonuria. |
| PubMedID- 23915015 | Background: depression is common in diabetes and associated with hyperglycemia, diabetes related complications and mortality. |
| PubMedID- 24408841 | In vitro studies suggest hyperglycemia associated with diabetes impair embryogenesis but in vivo investigations on maternal hyperglycemic insult and early embryo development are scarce. |
| PubMedID- 23717171 | Under certain pathologic conditions (e.g., oxidative stress due to hyperglycemia in patients with diabetes), age formation can be increased beyond normal levels. |
| PubMedID- 22864290 | On multivariate analysis, stress hyperglycemia in patients without diabetes was an independent predictor of msi. |
| PubMedID- 21193614 | Furthermore, a vicious cycle might occur in individuals with established diabetes of osa leading to hyperglycemia, requiring increasing glucose-lowering treatment, which could in turn cause weight gain and worsen the sleep apnea. |
| PubMedID- 23584372 | Type 2 diabetes consists of progressive hyperglycemia, insulin resistance, and pancreatic beta-cell failure which could result from glucose toxicity, inflammatory cytokines, and oxidative stress. |
| PubMedID- 25409255 | diabetes was strongly associated with hyperglycemia (table 2). |
| PubMedID- 21318185 | Only a handful of genes have been shown to affect development of hyperglycemia in diabetes mouse models. |
| PubMedID- 23439632 | Lack of suppression of glucagon is known to contribute to postprandial hyperglycemia in diabetes (25), and, contrary to our expectation, bariatric surgery did not restore this defect. |
| PubMedID- 24375463 | Introduction: hyperglycemia associated with diabetes mellitus (dm) has adverse impacts on peripheral nerve connective tissue structure, and there is preliminary evidence that nerve biomechanics may be altered. |
| PubMedID- 26171401 | However, whether the use of exogenous insulin (i.e., human insulin or insulin analogues) for treating hyperglycemia in patients with diabetes actually increases the risk of breast cancer is the subject of recent debate . |
| PubMedID- 21521130 | Introduction: in preliminary clinical studies, aleglitazar, a new dual ppar-alpha-gamma agonist, has been demonstrated to improve hyperglycemia and dyslipidemia in patients with type 2 diabetes mellitus. |
| PubMedID- 24532508 | Our results indicated that we were able to induce hyperglycemia with type 2 diabetes and establish a chronic stress model in mice. |
| PubMedID- 23454717 | Non-enzymatic glycation, which refers to the spontaneous binding of reducing sugars to free amino groups, is increased in diabetes mellitus because of hyperglycemia and is amplified by oxidative processes ('glycoxidation'). |
| PubMedID- 23799024 | The vascular complications in diabetes are causally associated with hyperglycemia-induced ros overproduction and a large body of evidence has suggested that endothelial dysfunction is caused by ros . |
| PubMedID- 26519255 | In the spontaneous non-obese diabetic (nod) mouse model, a single injection of ascs reversed hyperglycemia associated with early-onset diabetes in 78 % of nod mice, by regulation of th1-biased immune response, expansion of regulatory t cells (tregs), and reduction of inflammatory cell infiltration in the pancreas . |
| PubMedID- 20508223 | It is interesting that pain and dysesthesias may precede the development of type 2 diabetes, and that with hyperglycemia or elevated free fatty acid levels there is increased flux through the mitochondrial respiration chain leading to increased oxidant stress, with elevated levels of superoxide production, and a consequent increase in production of metabolites such as dihydroxyacetone phosphate, which is converted into the age precursor methylglyoxal (mg). |
| PubMedID- 24348462 | Overt diabetes mellitus – with hyperglycemia and severe insulin deficiency as prominent features – can be considered a disorder of domestication in that affected cats would die without treatment. |
| PubMedID- 23633864 | The oxidative degradation of fructosamines may contribute to the oxidative stress found in hyperglycemia associated with diabetes mellitus. |
| PubMedID- 21193625 | The ada and the easd published an expert consensus statement on the approach to management of hyperglycemia in individuals with type 2 diabetes (82). |
| PubMedID- 25927597 | In recent years, selective sglt2 inhibitors have been developed and are now in clinical use for the treatment of hyperglycemia in patients with type 2 diabetes mellitus . |
| PubMedID- 23295502 | Clinical trial results have shown further that two glp-1 receptor agonists (glp-1 ras), exenatide and liraglutide, which are approved for the treatment of hyperglycemia in patients with type 2 diabetes, also produce weight loss in overweight subjects without diabetes. |
| PubMedID- 25633134 | Among the many complications of type 2 diabetes mellitus (t2dm) arising from prolonged hyperglycemia, as well as from comorbid conditions such as hypertension, is chronic kidney disease (ckd), which is present in up to 40% of patients with t2dm 1. |
| PubMedID- 21457068 | Relationship among a1c, hypoglycemia, and hyperglycemia in japanese with type 2 diabetes--results from continuous glucose monitoring data. |
| PubMedID- 24339286 | Previous studies also suggested that the progression of atherosclerosis may be independently associated with long-term hyperglycemia in patients with established diabetes.19,20 the present study evaluated the usefulness of ms compared with diabetes as a prognostic concept in patients with cli treated with pta, which is an effective therapeutic method for salvaging limbs from both major and minor amputation.21,22 the results showed that ms was not associated with adverse clinical outcomes, but that diabetes had an incremental impact on minor amputations and primary patency in cli patients treated with pta during the 2-year follow-up. |
| PubMedID- 21713142 | Experimental diabetes mellitus-induced hyperglycemia produced a significant decrease in tail flick latency time. |