PedAM
Pediatric Disease Annotations & Medicines
| Disease | hyperglycemia |
| Symptom | |diabetes |
| Sentences | 382 |
| PubMedID- 21941533 | diabetes initiated due to hyperglycemia has a wide spectrum of disease manifestations as it leads to increased susceptibility of oxidative stress ultimately damaging various organs . |
| PubMedID- 20548844 | Typical symptoms of diabetes due to hyperglycemia (polyphagia, polyuria, and weight loss) were found in 63.3% of the young group, while they were found only in 29.9% of the older group (p < 0.05). |
| PubMedID- 23882051 | However, reducing hyperglycemia in individuals with type 2 diabetes has not been clearly associated with a decreased risk of developing cancer (49,50). |
| PubMedID- 26197936 | These inconsistencies may be due to the extent and duration of hyperglycemia as patients with type 2 diabetes may remain undiagnosed and therefore untreated for years, whereas the rats in this study were only diabetic for a period of 4 weeks. |
| PubMedID- 23835327 | It has been established that ca(v)3.2 t-type voltage-gated calcium channels (t-channels) play a key role in the sensitized (hyperexcitable) state of nociceptive sensory neurons (nociceptors) in response to hyperglycemia associated with diabetes, which in turn can be a basis for painful symptoms of peripheral diabetic neuropathy (pdn). |
| PubMedID- 21775756 | However, the failure to completely normalize fasting hyperglycemia in patients with type 2 diabetes appears to be consistent with both clinical practice and previous clinical studies (14) and provides a rationale for adding complimentary treatment options, such as short-acting insulin (24) or incretin-based therapies (25), if normoglycemia cannot be achieved with basal insulin alone. |
| PubMedID- 22807634 | This process of nonenzymatic glycation is exacerbated in diabetes due to chronic hyperglycemia and accompanying reactive carbonyl stress. |
| PubMedID- 24858947 | hyperglycemia resulting from type 2 diabetes mellitus (t2dm) is the main cause of diabetic complications such as retinopathy and neuropathy. |
| PubMedID- 22829848 | Children with type 2 diabetes, maturity-onset diabetes of youth, transient hyperglycemia, and diabetes caused by chemotherapy or cystic fibrosis are excluded from the nldd and thus were not included in the study. |
| PubMedID- 24159092 | The hyperglycemia in diabetes may impose cellular stress on the retina. |
| PubMedID- 25284699 | Glucagon-like peptide-1 receptor (glp-1) agonists and dipeptidyl-peptidase-4 (dpp-4) inhibitors are therapies that are used to treat hyperglycemia in patients with type 2 diabetes mellitus. |
| PubMedID- 23166623 | Type 2 diabetes (t2d) is associated with dyslipidemia, hyperglycemia, insulin resistance, and defects in insulin secretion from pancreatic beta cells 1. |
| PubMedID- 23649520 | hyperglycemia in patients with type 2 diabetes is resolved shortly after roux-en-y gastric bypass (rygb), suggesting that mechanisms independent of weight loss contribute to the improvement in glycemic control (1–4). |
| PubMedID- 23755276 | Chronic hyperglycemia in diabetes is associated with cardiovascular disease and microvascular pathologies in the retina, kidney and peripheral nerves . |
| PubMedID- 26253538 | Secondly, we sought to investigate the effect of glp-1 modulation on myocardial function in the setting of hyperglycemia in patients with type 2 diabetes mellitus (t2dm). |
| PubMedID- 25756053 | We conclude that hyperglycemia, which results from maternal diabetes and precedes embryo implantation, deregulates the intrauterine developmental timeline, restricts embryo-fetal growth, and primarily delays the remodeling and maturation of the structures derived from neural crest cells. |
| PubMedID- 20393151 | Objective: an increase in the rate of gluconeogenesis is largely responsible for the hyperglycemia in individuals with type 2 diabetes, with the antidiabetes action of metformin being thought to be achieved at least in part through suppression of gluconeogenesis. |
| PubMedID- 21300843 | hyperglycemia in diabetes causes abnormal carbohydrate metabolism and the production of advanced glycation end products, leading to alteration of gene expression and activities of the cellular glycosyltransferases and glycosidases (18). |
| PubMedID- 24615580 | neutropenia, diabetes with blood hyperglycemia and low ph, fe overload, corticosteroid therapy, and direct inoculation as a result of trauma are the main risk factors. |
| PubMedID- 23243444 | Chronic hyperglycemia in diabetes is associated with long-term damage, dysfunction, and eventually the failure of organs, especially eyes, kidneys, nerves, and the cardiovascular system . |
| PubMedID- 25050258 | hyperglycemia during diabetes results in cognition impairment. |
| PubMedID- 24790413 | Basal-bolus insulin therapy is an ideal regimen for improving uncontrolled hyperglycemia in patients with diabetes mellitus.1 prandial premixed insulin therapy (ppt), injected three times a day, is also effective for glycemic control in type 2 diabetics.2–9 further, ppt is convenient for patients, because it requires only a single insulin preparation. |
| PubMedID- 24296718 | A transgenic mouse model that expresses a constitutively active mutant of human ikk2 dependent on pdx-1 promoter activity (ikk2-ca(pdx-1)) spontaneously develops full-blown immune-mediated diabetes with insulitis, hyperglycemia, and hypoinsulinemia. |
| PubMedID- 23267675 | Twenty-two technical knowledge questions involved such concepts as the target age for diabetes testing, the benefits of exercise, hyperglycemia, groupings of foods and their exchange list, ideal body weight, and ketoacidosis. |
| PubMedID- 22548951 | Objective: to observe the effect of the dawn phenomenon on basal glucose and postbreakfast hyperglycemia in patients with type 1 diabetes treated with once-nightly insulin glargine and premeal insulin lispro. |
| PubMedID- 21931813 | Also increasing in incidence is type ii diabetes mellitus (t2d), associated with hyperglycemia, insulin-resistance, and hyperlipidemia , 7. |
| PubMedID- 25239210 | Constant hyperglycemia in individuals with type 2 diabetes can cause microvascular and macrovascular complications that lead to early morbidity and mortality. |
| PubMedID- 20811038 | The former is thought to be relevant to the pathogenesis of iatrogenic hypoglycemia and the latter to that of hyperglycemia in diabetes (12,13,40). |
| PubMedID- 25878764 | In support, the pathophysiologic perturbations connected with obesity-related diabetes are robustly associated with hyperglycemia-induced oxidative stress . |
| PubMedID- 24843713 | In japan, several cases of severe hyperglycemia in patients with type 2 diabetes after initiation of the glp‐1 receptor agonist, liraglutide, as replacement for insulin were reported15. |
| PubMedID- 25950009 | Increased formation of glyoxal and methylglyoxal and oxidative stress in hyperglycemia associated with diabetes has been linked to microvascular complications—including diabetic nephropathy . |
| PubMedID- 22446165 | Recent work reveals that hyperglycemia in diabetes triggers nutrient excess in neurons that, in turn, mediates a phenotypic change in mitochondrial biology through alteration of the amp-activated protein kinase (ampk)/peroxisome proliferator-activated receptor gamma coactivator-1alpha (pgc-1alpha) signaling axis. |