PedAM
Pediatric Disease Annotations & Medicines
| Disease | hyperglycemia |
| Symptom | |diabetes |
| Sentences | 382 |
| PubMedID- 22496878 | We have recently identified selenoprotein p (sep) as a liver-derived secretory protein that causes insulin resistance and hyperglycemia in patients with type 2 diabetes 1. |
| PubMedID- 26528798 | Skeletal muscle is the principal site for postprandial glucose utilization and augmenting the rate of glucose utilization in this tissue may help to control hyperglycemia associated with diabetes mellitus. |
| PubMedID- 23761972 | Sitagliptin (januvia merck, whitehouse station, nj, usa) is a highly selective dipeptidyl peptidase-4 (dpp-4) inhibitor available for the treatment of hyperglycemia in patients with type 2 diabetes,40,41 and simvastatin (zocor™ merck) is an hmg-coa reductase inhibitor available as an adjunctive treatment to diet for reducing elevated ldl-c and other lipids in patient with primary hypercholesterolemia and is indicated for reducing the risk of cardiovascular mortality.42 an fdc tablet of sitagliptin and simvastatin (juvisync™ merck) has been approved and provides an option for use in patients for whom treatment with both sitagliptin and simvastatin is appropriate. |
| PubMedID- 22699799 | hyperglycemia occurs in patients with poorly controlled diabetes mellitus and contributes to bone resorption and increased susceptibility to bacterial infections. |
| PubMedID- 24616659 | The consequences of poor glucose homeostasis are well-known: hyperglycemia associated with uncontrolled diabetes can lead to cardiovascular disease, neuropathy and nephropathy, while hypoglycemia can lead to convulsions, loss of consciousness, coma, and even death. |
| PubMedID- 26167540 | hyperglycemia in diabetes mellitus causes oxidative stress and pericyte depletion from the microvasculature of the brain thus leading to the blood-brain barrier (bbb) disruption. |
| PubMedID- 24843720 | hyperglycemia in diabetes is usually associated with accelerated age formation. |
| PubMedID- 24735134 | Conclusions: opt2mise will represent the largest studied homogeneous cohort of type 2 diabetes patients with persistent hyperglycemia despite optimized mdi therapy. |
| PubMedID- 26442119 | Implication of cardiovascular complications including cardiomyopathy in diabetes can be attributed to hyperlipidemia, hyperglycemia, and oxidative stress which promote atherosclerosis . |
| PubMedID- 20299466 | (13) provided evidence that posthypoglycemic hyperglycemia in patients with type 1 diabetes is the result of counterregulatory hormonal response to hypoglycemia in concert with prevalent plasma insulin concentration, and that all of the hormones but glucagon may play a role. |
| PubMedID- 25325279 | hyperglycemia in patients with type 2 diabetes is caused by multiple defects, including insulin resistance, impaired insulin secretion, and excessive hepatic glucose production. |
| PubMedID- 23185367 | Hepatic overproduction of glucose is a prominent contributor to hyperglycemia in patients with type 2 diabetes, and this overproduction may be a consequence of chronic and postprandial hyperglucagonemia , . |
| PubMedID- 24843599 | hyperglycemia in diabetes is due to the insufficient action of insulin, and cognitive impairment is not only closely associated with hyperglycemia, but also with the action of insulin. |
| PubMedID- 24550684 | The initial stage of development of nephropathy, incipient nephropathy, is characterized by the onset of persistent microalbuminuria and hyperfiltration.3 over the years the mechanisms of hyperglycemia leading to diabetes complications, specifically nephropathy, have been deciphered, but not totally. |
| PubMedID- 24695667 | Important early findings in incretin biology include proof-of-concept studies showing glp-1 infusion improves hyperglycemia in patients with type 2 diabetes . |
| PubMedID- 21341505 | Nonenzymatic glycation of proteins or maillard reaction is increased in diabetes mellitus due to hyperglycemia and leads to several complications such as blindness, heart disease, nerve damage and kidney failure. |
| PubMedID- 24963915 | Based on these studies and our current results, we propose that high glucose or hyperglycemia in diabetes shifts mitochondrial dynamics to fission, leading to mitochondrial fragmentation, which sensitizes mitochondria to bax attack, cytochrome c release and apoptosis during acute injury. |
| PubMedID- 25593844 | Standard tests for hyperglycemia in diabetes, such as fasting glucose and hemoglobin (hba1c), are currently not recommended for gdm screening. |
| PubMedID- 24486986 | hyperglycemia in diabetes results in the glycation of long-lived proteins. |
| PubMedID- 24332968 | Beta cell failure in type 2 diabetes (t2d) is associated with hyperglycemia, but the mechanisms are not fully understood. |
| PubMedID- 22096320 | in hyperglycemia associated with diabetes, the use of aldose reductase inhibitors has shown efficacy in attenuating diabetic complications. |
| PubMedID- 22196774 | His laboratory blood values showed a non-regulated diabetes mellitus with hyperglycemia of 32 mmol/l, white blood cell count of 18 × 109/l with 81.6% polymorphonuclear cells (pmns), elevated c-reactive protein (crp), hemoglobin, sodium and creatinine. |
| PubMedID- 25663437 | To mimic hyperglycemia in diabetes patients, the influence of elevated glucose levels on the actions of the different growth factors was also studied: ibrec were cultivated for 3 days in medium containing 3 g/l (≈17 mm) d-glucose instead of the normal 1 g/l (≈5.6 mm) d-glucose before vegf-a165 and vegf-b were added. |
| PubMedID- 22086363 | In the surgical population, hyperglycemia with or without diabetes mellitus may be unrecognized. |
| PubMedID- 24807533 | Transient carotid artery occlusion causes ischemia/reperfusion (i/r) injury resulting in neuron and pancreatic beta-cell death with consequential post-stroke hyperglycemia, which can lead to diabetes and may accelerate the development of alzheimer's disease. |
| PubMedID- 24876449 | Background: vascular dysfunction due to hyperglycemia in individuals with diabetes is a factor contributing to distal symmetric polyneuropathy (dspn). |
| PubMedID- 20678212 | The current study further documents that even mild hyperglycemia consistent with pre-diabetes is related to higher complication rates in patients over the age of 65. |
| PubMedID- 23320026 | hyperglycemia associated with diabetes mellitus can be controlled by diet management, exercise, oral hypoglycemic agents, and insulin therapy. |
| PubMedID- 24396690 | In 1992, it was first revealed that acute intravenous glp-1 infusion (for 30 or 210 minutes) significantly reduced postprandial hyperglycemia in patients with type 2 diabetes . |
| PubMedID- 21562080 | We hypothesize that hyperglycemia in diabetes impairs hypothalamic glucose sensing to lower glucose production, and changes of glucose transporter-1 (glut1) in the hypothalamic glial cells are responsible for the deleterious effects of hyperglycemia in vivo. |
| PubMedID- 22842610 | Self-monitoring of blood glucose is the standard of care in management of hyperglycemia among patients with diabetes mellitus. |
| PubMedID- 22235198 | The inbred mouse strain kk/ta, established as a diabetic strain in japan, spontaneously exhibits characteristics of type 2 diabetes associated with fasting hyperglycemia, glucose intolerance, hyperinsulinemia, mild obesity, dyslipidemia, and albuminuria. |
| PubMedID- 26060538 | One approach used to control hyperglycemia in patients with diabetes is the use of agents such as acarbose, which inhibits α-glucosidase activity and subsequently impairs the digestion of carbohydrates and delays glucose absorption after a meal 4. |
| PubMedID- 23363608 | Due to unrecognized diabetes complicated with infection, extreme hyperglycemia, even hyperglycemic hyperosmolar state or diabetic ketoacidosis, may occur. |
| PubMedID- 26581389 | The major novelty of this study is that experimentally induced acute hyperglycemia with no preceding diabetes diminishes cardioprotective effect of riperc. |
| PubMedID- 23435159 | Inpatient hyperglycemia in patients, with or without diabetes, is associated with poor hospital outcomes, including prolonged hospital stay, infections, and disability after hospital discharge, and death (1–3). |
| PubMedID- 22454632 | hyperglycemia in diabetes also stimulates toll-like receptor (tlr) signaling, which results in prolonged inflammation and tissue damage. |
| PubMedID- 23074234 | Objective: our objective was to observe the optimal management of hyperglycemia in patients with diabetes or impaired glucose tolerance receiving renal transplantation. |
| PubMedID- 20103560 | Moreover, information from epidemiology has led to several mechanistic studies and the elucidation of molecular level insights how insulin resistance and hyperglycemia lead to diabetes complications. |
| PubMedID- 21386984 | hyperglycemia in diabetes can cause up to four-fold increases in neuronal glucose levels. |
| PubMedID- 26114112 | In response to hyperglycemia in patients with diabetes, various metabolic mechanisms contribute to the pathogenesis of diabetic complications. |
| PubMedID- 22361035 | Chronic hyperglycemia in diabetes leads to free radicals overproduction, which contributes to the development of diabetic nephropathy. |
| PubMedID- 22111038 | It is well established that chronic hyperglycemia in patients with type 2 diabetes mellitus causes progressive deterioration of β-cell function. |
| PubMedID- 20519662 | Because we observed that cognitive decline was greater in prevalent diabetic patients than in incident diabetic patients and individuals without diabetes, duration of exposure to hyperglycemia could be the main factor that induces and maintains cognitive decline. |
| PubMedID- 21655098 | Although egb761 has beneficial effects on blood circulation and hyperglycemia in patients with diabetes, direct studies on its effects against atherosclerosis are limited. |
| PubMedID- 23610083 | A girl (now 17 years old; bmi, 20.1 kg/m2) had diabetes presenting with moderate hyperglycemia without dka diagnosed at the age of 4 years. |
| PubMedID- 25810947 | It has also been demonstrated that acute hyperglycemia in people with type 2 diabetes significantly impaired speed of information processing, working memory, and some aspects of attention . |
| PubMedID- 26504840 | In 2013, chinese hospital association (cha) set up a systematic management program of hyperglycemia in inpatients with type 2 diabetes (t2d) admitted to top tertiary hospital to improve the care of inpatients with t2d in china and, in particular, to learn the profile of hypoglycaemia and associated factors. |
| PubMedID- 21977459 | Diabetic polyneuropathy (dpn) is one of the microvascular complications of diabetes that is attributed to chronic hyperglycemia and is a common cause of morbidity in patients with diabetes mellitus 5. |
| PubMedID- 22923999 | hyperglycemia in diabetes results from defects in insulin secretion, insulin action, or, most commonly, both. |