PedAM
Pediatric Disease Annotations & Medicines
| Disease | hyperglycemia |
| Symptom | |diabetes |
| Sentences | 382 |
| PubMedID- 20150286 | Despite their hyperglycemia, patients with type 2 diabetes tend to have elevated fasting glucagon levels and exaggerated glucagon responses to meal ingestion (5). |
| PubMedID- 21115766 | We hypothesized that postbreakfast hyperglycemia in subjects with type 2 diabetes could be improved nonpharmacologically by using a high-protein, low-carbohydrate prebreakfast snack. |
| PubMedID- 24465790 | Thus, hyperglycemia in diabetes enhances the formation of ages and leads to fluorescent or non-fluorescent products, sometimes creating cross-links . |
| PubMedID- 24907624 | diabetes was associated with weight loss, hyperglycemia, and oxidative stress as reflected by increased serum malondialdehyde (mda) concentrations. |
| PubMedID- 21159853 | After extending previous evidence that leptin infusion directly into the lateral cerebral ventricle ameliorates hyperglycemia in rats with streptozotocin-induced uncontrolled diabetes mellitus, we showed that the underlying mechanism is independent of changes of food intake, urinary glucose excretion, or recovery of pancreatic beta-cells. |
| PubMedID- 24772447 | But this ability of the endocrine pancreas seems to be attenuated in type 2 diabetes which finally leads to hyperglycemia and blood glucose fluctuations . |
| PubMedID- 24319123 | Conclusions: these results suggest vulnerability of the developing brain in young children to effects of type 1 diabetes associated with chronic hyperglycemia and glucose variability. |
| PubMedID- 26398746 | Nevertheless, the long-term consequence of elevated pkc-phosphorylation/activity should be considered in diabetes with chronic hyperglycemia . |
| PubMedID- 25298619 | diabetes is associated with hyperglycemia and increased thrombin production. |
| PubMedID- 24757043 | In our obese and overweight population, three patients have impaired glucose tolerance, one has cf-related diabetes (cfrd) with fasting hyperglycemia, three have hypertension, and one has obstructive sleep apnea (osa). |
| PubMedID- 22524271 | Diets based on refined carbohydrate foods that are quickly digested, absorbed, and metabolized (i.e., high glycemic index diets) have been associated with increased risk of lifestyle diseases in particular with an increased risk of type 2 diabetes, because of postprandial hyperglycemia and hyperinsulinemia related to eating high-gi carbohydrates. |
| PubMedID- 20009088 | The influence on the ubiquitin-proteasome system of hyperglycemia associated with diabetes in this regard has yielded seemingly contradictory results. |
| PubMedID- 23816355 | Exercise has been widely recognized to ameliorate insulin resistance and hyperglycemia in individuals with type 2 diabetes mellitus (t2dm) . |
| PubMedID- 23418497 | Both type 1 and type 2 diabetes lead to hyperglycemia that further results in a number of complications, including damage to nerves (diabetic neuropathy) 2. |
| PubMedID- 25633683 | Postprandial hyperglycemia is common in patients with type 2 diabetes (t2dm) . |
| PubMedID- 20130740 | Therefore, these results suggest that hps3 may partly ameliorate hyperglycemia and hyperlipidemia associated with type 2 diabetes through increased insulin secretion, inhibition of lipid peroxidation, promotion of sensitivity to insulin, suppression of gluconeogenesis and reduction in the biosynthesis fatty acid, cholesterol and cell cytokines related to insulin resistance, and it could be a useful adjunct therapy to a proven first-line therapy for type 2 diabetes using metformin. |
| PubMedID- 26562793 | According to the recent studies, hyperglycemia associated with diabetes plays the role of stabilizing the collagen network through giving rise to cross-linking of collagen network in the aortic wall media. |
| PubMedID- 23841037 | The risk of microalbuminuria is correlated with plasma glucose level, and the duration of hyperglycemia in patients with diabetes (9, 10). |
| PubMedID- 23378612 | Chronic hyperglycemia leads to development of diabetes-associated microvascular, macrovascular, and neurologic complications, which can be delayed by intensive insulin therapy (1). |
| PubMedID- 22178606 | In the latter, the process is further aggravated by hyperglycemia, leading to diabetes complications of cns. |
| PubMedID- 21852673 | Furthermore, experimental diabetes in rats with insulinopenia and hyperglycemia provokes mucosal hypertrophy and increases mrna and protein expression of glut2, glut5, and sglt1 (16). |
| PubMedID- 25922827 | The increase in the cu2+ levels in patients with diabetes might be attributed to hyperglycemia that may stimulate glycation and release of cu2+ from copper-containing enzymes. |
| PubMedID- 24895642 | Diabetic retinopathy is a microvascular complication of diabetes correlated with chronic hyperglycemia 1. |
| PubMedID- 23193216 | Pizza is widely recognized to cause marked late postprandial hyperglycemia in patients with type 1 diabetes (11). |
| PubMedID- 26084668 | However, the optimal treatment of hyperglycemia in patients with diabetes to reduce the progression of hf has not been well studied. |
| PubMedID- 20042777 | Unexplained hyperglycemia in a patient with type 1 diabetes may suggest impending dka, and monitoring of ketones should therefore be performed. |
| PubMedID- 22618776 | Msc infusion ameliorated hyperglycemia in rats with type 2 diabetes (t2d). |
| PubMedID- 24729889 | Chronic hyperglycemia resulting from diabetes brings about a rise in oxidative stress due to overproduction of reactive oxygen species (ros) as a result of glucose-autoxidation and protein glycosylation. |
| PubMedID- 22114719 | However, by one month after birth, transgenic mice expressing any of the three ran variants exhibited overt diabetes, with hyperglycemia, reduced insulin production, and nearly complete loss of islet number and islet mass, in vivo. |
| PubMedID- 25422773 | Diabetic peripheral neuropathy (dpn) is a well-known microvascular complication of type 2 diabetes mellitus attributed to chronic hyperglycemia, and is defined as the presence of peripheral nerve dysfunction in diabetics after exclusion of other causes3–6. |
| PubMedID- 23116444 | The term diabetic cardiomyopathy refers to a state of cardiac dysfunction independent of associated coronary artery disease that arises within weeks of hyperglycemia (hg) leading to longer term diabetes mellitus (dm) 1. |
| PubMedID- 20042772 | As retinopathy is estimated to take at least 5 years to develop after the onset of hyperglycemia (298), patients with type 1 diabetes should have an initial dilated and comprehensive eye examination within 5 years after the onset of diabetes. |
| PubMedID- 25349949 | Conclusion: depression in type 2 diabetes was closely associated with hyperglycemia and hypoglycemia, which might be partly mediated through poor treatment adherence. |
| PubMedID- 20836897 | Multiple and complex pathways promote the deleterious effects of hyperglycemia in diabetes, ultimately leading to micro- and macrovascular disease. |
| PubMedID- 23614630 | The position statement on the management of hyperglycemia in patients with type 2 diabetes mellitus issued in 2012 by the american diabetes association and the european association for the study of diabetes contains significant improvements over the 2009 version, including an emphasis on patient-centered care, enhanced strategies for lifestyle modification, a focus on comprehensive cardiovascular risk reduction, and increased pharmacotherapy choices. |
| PubMedID- 24324521 | The hyperglycemia in diabetes produces superoxide anions, which generate hydroxyl radicals, promoting cell membrane damages as a result of lipid peroxidation and protein glycation of membrane . |
| PubMedID- 23209929 | It has also been suggested that chronic exposure to hyperglycemia and hyperinsulinemia, in patients with type 2 diabetes, could contribute to the proliferation of hepatic stem cells, at higher risk for malignant transformation . |
| PubMedID- 21307777 | Aim: hyperglycemia in diabetes mellitus (dm) may be one of the most important factors responsible for the development of oxidative stress, which promotes the main complications in dm patients. |
| PubMedID- 23339473 | As ogtts should be avoided in patients with severe diabetes because of the risk of hyperglycemia, the homeostasis model assessment of insulin resistance (homa-ir) index is widely used in clinical practice and in clinical studies instead 4. |
| PubMedID- 20724647 | The major contributor to the lack of ego suppression and, thus, to the exaggerated postprandial hyperglycemia in diabetes seems to be an increase in gluconeogenesis (21). |
| PubMedID- 23231438 | In clinical trials, both exenatide formulations reduced hyperglycemia in patients with type 2 diabetes mellitus (t2dm) and were associated with weight loss. |
| PubMedID- 23691290 | Increase in tnf-α and il-6 during diabetes may be due to hyperglycemia related to oxidative stress and inflammation . |
| PubMedID- 22811666 | Endothelial cell dysfunction, an early vascular complication in diabetes, has been associated with hyperglycemia-induced oxidative stress. |
| PubMedID- 24843412 | Clinically, the pulmonary system appears to be protected from the toxic actions of hyperglycemia because patients with type 1 diabetes are relatively free from vascular pathologies of the pulmonary system. |
| PubMedID- 22683753 | hyperglycemia in association with diabetes mellitus makes esrd patients resistant to hcy-lowering therapy. |
| PubMedID- 21046527 | Aleglitazar, being developed by roche holding, is a dual agonist for ppargamma and pparalpha for the potential simultaneous treatment of hyperglycemia and dyslipidemia in patients with type 2 diabetes mellitus (t2dm). |
| PubMedID- 21307380 | Ages, increased in diabetes as a result of both hyperglycemia and oxidative stress, are observed in both myelinated and unmyelinated fibers of sural, peroneal, and saphenous nerves of individuals with diabetes (6,7) and may contribute to the segmental demyelination of diabetic neuropathy (8). |
| PubMedID- 26198996 | Conclusions: following colorectal operations, superficial ssi, sepsis, and death are associated with postoperative serum hyperglycemia in patients without diabetes, but not those with diabetes. |
| PubMedID- 22745633 | hyperglycemia in individuals with diabetes mellitus usually compromises myocardial contractile function and energy metabolism independent of macro- and microvascular coronary anomalies . |
| PubMedID- 20067962 | Type 2 diabetes constitutes a group of metabolic aberrations including hyperglycemia, inflammation, and insulin resistance that increase the risk of cardiovascular disease (1). |