eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | narcolepsy |
| Symptom | |cataplexy |
| Sentences | 170 |
| PubMedID- 21486708 | Conclusions: the multimodal, dreamlike aspect of hallucinations in narcolepsy with cataplexy could transiently impair the patients' insight. |
| PubMedID- 23821583 | Results: we found an average 64% increase in the number of histamine neurons in human narcolepsy with cataplexy, with no overlap between narcoleptics and controls. |
| PubMedID- 26251634 | We report on two narcolepsy patients with multiple daily cataplexy episodes, one of whom had been effectively treated with ghb, but had to discontinue it for unrelated medical reasons. |
| PubMedID- 21532956 | In addition, narcolepsy with cataplexy in our clinic population appeared to begin at a younger age than usually reported in other studies. |
| PubMedID- 22435405 | The autoimmune sleep disorder narcolepsy with cataplexy is caused by a loss of hypocretin-producing neurons in the brain . |
| PubMedID- 20160349 | Elisa analysis showed that sera from narcolepsy patients with cataplexy had higher trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia, multiple sclerosis, or other inflammatory neurological disorders. |
| PubMedID- 24416019 | Dko mice display the most profoundly disturbed sleep phenotype of all three models: narcolepsy with cataplexy (transient episodes of behavioral arrest) (kalogiannis et al., 2011). |
| PubMedID- 20810312 | Methods: nineteen drug-naive narcolepsy patients with cataplexy (10 males, 9 females, and mean age 28.5 years) and 25 age- and sex-matched healthy controls were recruited. |
| PubMedID- 24363733 | The drug is recommended in obsessive compulsive disorders (ocd), in cataplexy associated with narcolepsy, and in depression when sedation is required (5-7). |
| PubMedID- 20689589 | narcolepsy with cataplexy is caused by a derangement of orexin (also known as hypocretin) signaling , . |
| PubMedID- 23526549 | This article reviews the contribution of neuroimaging to the pathophysiology of narcolepsy with cataplexy, focusing on the most recent developments. |
| PubMedID- 21387813 | Conclusions: neurophysiological procedures (mslt) and biological markers are necessary in the diagnosis of narcolepsy with cataplexy and hypersomnia without cataplexy. |
| PubMedID- 21697009 | Background: narcolepsy with cataplexy (nc) is a disabling disorder characterized by excessive daytime sleepiness and abnormal rapid eye movement (rem) sleep manifestations, due to a deficient hypocretin/orexin neurotransmission. |
| PubMedID- 25534169 | Pseudo-cataplexy, a form of "psychogenic" narcolepsy, "pseudo-parasomnia" and pnes can have a similar presentation. |
| PubMedID- 25969754 | Consistently, disruption of the orexin system leads to the sleep disorder narcolepsy with cataplexy in humans as well as in animal models . |
| PubMedID- 19555382 | Although a close association between human leucocyte antigen (hla) and human narcolepsy with cataplexy suggests an involvement of autoimmune mechanisms, this has not yet been proved. |
| PubMedID- 26227560 | Following the mass vaccinations against pandemic influenza a/h1n1 virus in 2009, a sudden increase in juvenile onset narcolepsy with cataplexy (nc) was detected in several european countries where as03-adjuvanted pandemrix vaccine had been used. |
| PubMedID- 23643651 | Background: to test if the hypocretin (orexin) neuropeptide precursor (hcrt) gene, hcrt, mutations are implicated in the development of narcolepsy with cataplexy deficiency in young children. |
| PubMedID- 23496005 | The aim of this study was to describe the clinical and psg characteristics of narcolepsy with cataplexy and their genetic predisposition by using the retrospective patient database of the european narcolepsy network (eu-nn). |
| PubMedID- 24297759 | Methods: we enrolled 181 consecutive patients (108 men, 73 women; mean age 37.6 +/- 16.6 years old; narcolepsy with cataplexy/narcolepsy without cataplexy = 131:50). |