eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hyperthermia |
| Comorbidity | |malaria |
| Sentences | 147 |
| PubMedID- 24884606 | A total of 297 febrile patients with suspected malaria based on clinical presentation were enrolled and screened for plasmodium parasites in the course of the study. |
| PubMedID- 24596021 | "comment: some of the authors are employed by the trial sponsors but all authors had access to data and assumed responsibility for reporting accuracy.ringwald 1996methodstrial design: randomized, parallel group, active controlled trialduration of trial: recruitment: april 1994 to may 1995participantsnumber randomized: 96age: 15 to 64 yearsgender: 42 males; 54 femalesinclusion criteria:acute falciparum malaria with fever within the past 24 hrs or a temperature above 37.5 °c at the time of consultationover 5000 asexual parasites/µlno signs and symptoms of severe and complicated malariano recent self-medicationexclusion criteria:pregnant womenmixed infectionsinterventionsintervention1. |
| PubMedID- 25604792 | Uncomplicated malaria consists of cycles of high fever and chills. |
| PubMedID- 21054891 | The results of this study suggest that it is worthwhile to perform blood films on hospitalized neonates with fever in malaria endemic regions since though it is rare, congenital and neonatal malaria does occur. |
| PubMedID- 21631932 | The role of fever in malaria is unclear. |
| PubMedID- 20409342 | The final models for anaemia and parasitaemia were adjusted for age, ethnicity, ses, clinical malaria (in the case of anaemia), current fever (for parasitaemia), district, and whether or not the child had slept under an itn the previous night. |
| PubMedID- 21750697 | However, based on the rdt results, at least 50% of patients during the cd weeks did not have malaria as cause of fever and were potentially therefore incorrectly treated with act only. |
| PubMedID- 24386229 | The fever guideline specifies that it is to be applied to patients with documented temperature elevation or history of fever in the past 24 hours because malaria, an important cause of febrile illness in mozambique, often presents with intermittent fever [35]. |
| PubMedID- 24996807 | The crude fraction of febrile episodes attributable to malaria was estimated at 91%. |
| PubMedID- 21056005 | Children in the control group who had malaria were admitted because of a febrile seizure at home, anaemia, or possible anaemia—children with uncomplicated malaria are generally not admitted. |
| PubMedID- 21787434 | Differentiating fever attributed to malaria from other fever by aetiology. |
| PubMedID- 21085872 | In areas of dengue transmission, delay in the diagnosis and treatment of malaria in patients with fever who reside in areas of malaria transmission can be due to the confusion between the clinical diagnoses of both diseases by nonspecialist doctors, among other factors. |
| PubMedID- 21575152 | Results of multivariate regression analysis of the association of fever with malaria when controlled for gender, age, residence, use of insecticide treated nets (itn) and wealth quintile. |
| PubMedID- 23937722 | Decreases in the proportion of febrile illnesses associated with malaria in many settings (d'acremont et al. |
| PubMedID- 23356837 | The availability of rapid diagnostic tests (rdts) allows rural health workers to reliably rule out malaria in fever patients. |
| PubMedID- 22958592 | In conclusion, urinary tract infections caused by multi drug resistant escherichia coli was identified as the most common cause of fever, which co-existed with malaria and bacteremia. |
| PubMedID- 20544032 | Vl was diagnosed in clinical suspects by high titer (≥1∶6,400) antibodies to leishmania (freeze-dried leishmania antigen supplied by the royal tropical institute, amsterdam, the netherlands) in a direct agglutination test (dat); or by microscopy of splenic or lymph node aspirates; or (since 2004) by rk39 rapid diagnostic test (diamed-it-leish supplied by diamed ag, cressier sur morat, switzerland); or on rare occasions when laboratories were not functioning, by clinical judgment (criteria: fever >2 weeks with exclusion of malaria and either splenomegaly or lymphadenopathy and wasting). |
| PubMedID- 22554149 | Background: although early diagnosis and prompt treatment is an important strategy for control of malaria, using fever to initiate presumptive treatment with expensive artemisinin combination therapy is a major challenge; particularly in areas with declining burden of malaria. |
| PubMedID- 25902716 | Between july and december 2013 a further seven individuals, who had been screened at least once during the acd programme and tested negative for malaria, presented with fever to the same dgh and were diagnosed with p. vivax malaria. |
| PubMedID- 20370920 | The presence of fever in conjunction with a positive malaria smear correlated with parasite density in p. falciparum infections (f1,34 = 8.48, p = 0.006), but not in p. vivax infections (f1,77 = 1.89, p = 0.174). |
| PubMedID- 24438177 | In addition, it is employed to treat hepatitis, cancer, microbial infections, and fever associated with malaria [7-9]. |
| PubMedID- 22815732 | Sepsis was defined as severe non-malaria febrile illness with fever, signs of shock including hypotension, tachypnoea or anuria these deaths could be further subdivided into confirmed infection with localizing signs or no localizing signs. |
| PubMedID- 22853699 | Furthermore, since syndromic treatment of fever with empiric anti-malarial therapy is not uncommon, persons with fever from hiv-1 or its complications could be more likely to receive empiric intermittent anti-malarial therapy for other disease states which might further lower the prevalence of sub-clinical malaria in this group. |
| PubMedID- 24069477 | Moreover, crp has already been used as a biomarker of malaria in febrile patients returning from tropical areas and in epidemiological investigations in endemic areas [22]. |
| PubMedID- 24160186 | The approach assumes that febrile individuals with malaria infection are no more or less likely to seek treatment than febrile individuals who do not harbour malaria infection. |
| PubMedID- 20849650 | The findings show: 1) no health facility or health worker was exposed to all components of the intervention; 2) the proportion of health workers who received the enhanced in-service training was 67%; 3) the proportion of febrile children with uncomplicated malaria treated with the first-line anti-malarial drug, artemether-lumefantrine (al), at health facilities where al was in stock increased from 76.9% (95%ci: 69.4, 83.1) to 87.6% (95% ci: 82.5, 91.5); 4) there were modest but non-significant improvements in dispensing and counseling practices; and 5) when the analyses were restricted to health workers who received the enhanced in-service training and/or had received new guidelines and job aids, no significant improvements in reported case-management tasks were observed compared to baseline. |
| PubMedID- 21740570 | The study considered patients at least two years old suffering from acute, uncomplicated plasmodium falciparum malaria with fever (axillary temperature ≥37.5°c) and a parasitaemia of between 1,000 and 100,000 trophozoites/μl in senegal and 2,000 to 200,000 trophozoites/μl in cameroon and ivory coast. |
| PubMedID- 24373481 | If fever had been used to diagnose malaria, 47.2% of the febrile women would have been unnecessarily treated. |
| PubMedID- 24415936 | One child had symptomatic malaria (parasitemia with a fever requiring treatment) at the time of the blood draw, and 17 (22%) had blood smears demonstrating parasitemia. |
| PubMedID- 21037109 | Vivax obtained from a febrile patient with clinical malaria from peru was subjected to whole-genome sequencing (30x coverage). |
| PubMedID- 26472130 | Overtreatment of fevers with antimalarials is a major global health challenge that has been described across malaria-endemic countries around the world. |
| PubMedID- 24626194 | For decades, a high importance was given to malaria as a cause of fever, which has led to an overestimation of its burden and at the same time an underestimation of other diseases. |
| PubMedID- 25890202 | However, more than half (57.2%) of febrile children with laboratory-confirmed negative malaria in a high malaria transmission area were prescribed anti-malarials compared to only 7.0% in a low malaria transmission area. |
| PubMedID- 24843017 | Among 1500 homesteads in coastal kenya we calculated (a) the fraction of febrile children with positive malaria smears per homestead, and (b) the mean age of children with malaria per homestead. |
| PubMedID- 23977655 | The classic presentation of malaria with paroxysms of fever is seen only in 50-70% of the patients. |
| PubMedID- 25008574 | Results: the system's effectiveness of delivering an act to febrile children diagnosed with malaria (parasitologically or clinically) was 31.4 and 42.4% in hospitals and health centres, respectively. |
| PubMedID- 24279720 | In zambia, for example, health workers diagnosed fewer than 30% of fever patients with a malaria rdt/blood slide following the introduction of a treatment protocol similar to that employed in png, even when rdts/microscopy were available [8]. |
| PubMedID- 21824389 | But there are malaria cases with high fever who can take oral medication, or cases with fever and diarrhea not thought to be due to malaria. |
| PubMedID- 21179555 | In the east african highlands, enso events may trigger heavy rainfall and raised temperatures and were associated with increased malaria in the southwestern highlands of uganda [48]. |
| PubMedID- 22169409 | Although detailed diagnostics were available for some women with fevers (≥37·5°c) caused by diseases other than malaria,23 the diagnosis of non-malaria febrile illness relied mainly on clinical findings. |
| PubMedID- 24741614 | Blood samples were collected in 2009 from forty-seven febrile patients diagnosed with malaria for p. vivax infection and treated at the tropical medicine foundation of amazonas a tertiary care centre in manaus (figure 1). |
| PubMedID- 20553598 | Rapid diagnostic tests were used to test for malaria in febrile school children (temperature ≥37.5°c). |
| PubMedID- 25563798 | At these senegal sites, patients were visited three times per week, and the present work makes no attempt to ‘correct’ the data for case detection frequency or to censor model-predicted fevers from being attributed to malaria if concurrent parasitaemia is low. |
| PubMedID- 25588165 | A multivariate regression model has been developed that utilized raman spectra of 20 malaria-infected, 10 non-malarial with fever, 10 healthy, and 6 dengue-infected samples to optically predict the malaria infection. |
| PubMedID- 20937094 | The cost-effectiveness decision model predicts the number of adequate diagnosis of febrile patients with suspected malaria and costs associated with each diagnosis. |
| PubMedID- 24475198 | malaria with fever and parasitaemia 5,000/µl or more: in the acd cohort the number of episodes per child ranged from 0 to 5, with a mean of 1.18. in the pcd cohort, the mean number of episodes per child was 0.89 (range: 0 to 6). |
| PubMedID- 21529365 | The strategy of presumptive treatment of all fevers with anti-malarials leads clinicians to believe that all fevers are due to malaria, resulting in a massive over-diagnosis [3,4], and more importantly to ignoring non-malaria causes of fever that have similar, or even higher case fatality rates than malaria [5,6]. |
| PubMedID- 24885909 | For most of the population (89%), fever with other classical malaria symptoms was an indication to visit a local clinic with a microscopist or other health officer. |
| PubMedID- 22835018 | In fact, a previous study performed in maputo, mozambique, has already evidenced that the fraction of febrile illness attributable to malaria is lower in hiv-positive adults than in hiv-negatives [10]. |
| PubMedID- 23231855 | Physicians and public health authorities should consider malaria in febrile patients returning or migrating from pakistan. |