PedAM
Pediatric Disease Annotations & Medicines
| Disease | arteriosclerosis |
| Phenotype | C0011847|diabetes |
| Sentences | 200 |
| PubMedID- 22022185 | It has been shown that atherosclerosis in patients with diabetes mellitus (dm) can lead to acute coronary artery disease, ischemic cerebral disease, and peripheral arterial disease (2). |
| PubMedID- 25992325 | Cardiovascular (cv) complications are an essential causal element of prospect in diabetes mellitus (dm), with carotid atherosclerosis being a common risk factor for prospective crisis of coronary artery diseases and/or cerebral infarction in dm subjects. |
| PubMedID- 20414371 | To date, the mcp-1 –2518 a>g polymorphism has been associated with coronary artery disease, nonfamilial idiopathic dilated cardiomyopathy, carotid atherosclerosis in patients with type 2 diabetes, myocardial infarction, ischemic heart disease, and hypertension [33–38]. |
| PubMedID- 24101925 | It has been reported that metabolic syndrome and insulin resistance are the major components of atherosclerosis risk in patients with diabetes and also in individuals without diabetes with insulin resistance [3, 20, 21], whereas the role of hyperglycemia in cardiovascular disease associated with type 2 diabetes is less clear [22]. |
| PubMedID- 22394699 | Association between apolipoprotein e polymorphism and subclinic atherosclerosis in patients with type 1 diabetes mellitus. |
| PubMedID- 24465662 | It is considered a key element in the development of atherosclerosis and associated with diabetes, insulin resistance, obesity and preeclampsia [14]–[17]. |
| PubMedID- 20194881 | Effect of rosiglitazone on progression of coronary atherosclerosis in patients with type 2 diabetes mellitus and coronary artery disease: the assessment on the prevention of progression by rosiglitazone on atherosclerosis in diabetes patients with cardiovascular history trial. |
| PubMedID- 22120969 | Glp-1 may prevent or delay the formation of atherosclerosis in diabetes mellitus by improving the function of enos. |
| PubMedID- 24678948 | Contribution of subcutaneous abdominal fat on ultrasonography to carotid atherosclerosis in patients with type 2 diabetes mellitus. |
| PubMedID- 22085839 | Synergistic effect between brap polymorphism and diabetes on the extent of coronary atherosclerosis in the chinese population. |
| PubMedID- 24423050 | The gstt1-null genotype and combined gstt1*0/gstm1*0 might be potential determinants of susceptibility to advanced atherosclerosis in patients with type 2 diabetes mellitus [16]. |
| PubMedID- 22461787 | A high-fat diet (hfd) provides a commonly used approach to induce obesity and insulin resistance in c57bl6 mice [37] and is also useful to study accelerated atherosclerosis associated with diabetes [38, 39]. |
| PubMedID- 19853860 | Conclusions: aimt is an earlier marker than cimt of preclinical atherosclerosis in children with type 1 diabetes mellitus and relates to known cardiovascular risk factors and metabolic control. |
| PubMedID- 24804267 | The mean car.int-r and car.int-l values, which were recognized as one of the important markers of atherosclerosis, of patients with diabetes are significantly higher than the control group (p < 0.01, for each). |
| PubMedID- 23223344 | The aim of this study was to evaluate and compare the degree of coronary atherosclerosis in patients with nondiabetes, prediabetes, and diabetes, according to the ada classification, by using coronary angioscopy. |
| PubMedID- 23387219 | Objective: to investigate whether serum cystatin c (cys c) concentration correlates with the severity of carotid atherosclerosis (cas) in patients with type 2 diabetes mellitus (dm). |
| PubMedID- 24612649 | Insulin resistance is present in most patients with type 2 diabetes and is associated with atherosclerosis [16], but the relationship between insulin resistance and exercise capacity in patients with both type 2 diabetes and cad is not clarified. |
| PubMedID- 22210567 | To better elucidate the role of type 1 diabetes in atherosclerosis, we excluded patients with type 2 diabetes and used as a control group of uremic patients without diabetes. |
| PubMedID- 24298454 | Conclusion: sh, the earliest form of thyroid failure, has negative metabolic effects on the affected subjects.sh could be one of the causes of secondary hyperlipidaemia and should be viewed as an independent risk factor for atherosclerosis, along with obesity, hypertension, diabetes, etc. |
| PubMedID- 22682537 | Furthermore, in multivariate logistic regression analysis, thigh circumference was an independent determinant factor for carotid atherosclerosis in patients with type 2 diabetes even after adjusting for other cardiovascular risk factors. |
| PubMedID- 25168108 | Correlations between serum levels of 25-hydroxyvitamin d and carotid atherosclerosis in patients with type 2 diabetes in shanghai. |
| PubMedID- 24318519 | This study aimed to assess relationship between mvp and the severity of coronary atherosclerosis in patients with diabetes mellitus (dm), stable cad and normal left ventricular ejection fractions. |
| PubMedID- 26089898 | Driven by hyperglycemia and oxidant stress, the effects of ages on vessel wall homeostasis may account for the rapidly progressive atherosclerosis associated with diabetes [32, 33]. |
| PubMedID- 22367281 | Low ghrelin serum levels were associated with advanced carotid atherosclerosis in patients with type ii diabetes mellitus15 and elderly patients with metabolic syndrome16, implicating the role of ghrelin as a novel atherosclerotic biomarker and predictive index of atherosclerosis. |
| PubMedID- 24477591 | It should be mentioned that there was no independent association of the analyzed polymorphisms with cad, neither in these studies nor in the study on genetically related slovenian population, where the c242t polymorphism was not associated with carotid atherosclerosis in patients with type two diabetes [29]. |
| PubMedID- 22817861 | The unique pattern of lower extremity atherosclerosis in diabetes is a critical determinant of the revascularization strategy. |
| PubMedID- 21747057 | Background: endothelial dysfunction contributes to the development of atherosclerosis in patients with diabetes mellitus, but the mechanisms of endothelial dysfunction in this setting are incompletely understood. |
| PubMedID- 20807873 | atherosclerosis is accelerated in patients with type 2 diabetes and underlies their higher incidence of cardiovascular disease (cvd) events. |
| PubMedID- 20108050 | Since postprandial lipoproteins are atherogenic, the delay in clearance of these particles could play an important role in the development of atherosclerosis in patients with diabetes mellitus. |
| PubMedID- 24373412 | Background: an increased leukocyte count is an independent risk factor for cardiovascular events, but the association between leukocyte subtype counts and carotid atherosclerosis in patients with diabetes has not been determined. |
| PubMedID- 25471794 | Protection from diabetes-induced atherosclerosis and renal disease by d-carnosine-octylester: effects of early vs late inhibition of advanced glycation end-products in apoe-null mice. |
| PubMedID- 23574730 | Postprandial hyperglycemia and/or hyperlipidemia can contribute to development of atherosclerosis in patients with type 2 diabetes mellitus (t2dm). |
| PubMedID- 25708055 | In conclusion, cumulative active and passive smoking exposures are significant risk factors for carotid atherosclerosis in patients with type 2 diabetes mellitus. |
| PubMedID- 23675198 | Although the exact cause of premature atherosclerosis in diabetes is not well understood, several independent risk factors such as hypertriglyceridemia and hypertension may contribute to coronary heart disease (8). |
| PubMedID- 24331102 | Conclusion: controlling abdominal obesity seems to have a significant impact on the progression of subclinical atherosclerosis in patients with diabetes, and therefore, more efforts should be made toward reducing waist circumference to inhibit overt atherosclerotic diseases. |
| PubMedID- 25953645 | Conclusions: the plasma level of mmp-7 and -12 are elevated in type 2 diabetes mellitus, associated with more severe atherosclerosis and an increased incidence of coronary events. |
| PubMedID- 22330623 | The gstt1-0 genotype and gstt1-0/gstm1-0 haplotype might be a potential determinants of susceptibility to advanced atherosclerosis in patients with type 2 diabetes mellitus. |
| PubMedID- 23735728 | Type 2 diabetes has been associated with accelerated atherosclerosis (11) and elevated systemic inflammation (12–14). |
| PubMedID- 21270185 | Research design and methods: the japanese primary prevention of atherosclerosis with aspirin for diabetes (jpad) trial was a prospective, randomized, open-label trial conducted throughout japan that enrolled 2,539 type 2 diabetic patients without a history of atherosclerotic diseases. |
| PubMedID- 25456820 | High-intensity statin therapy and regression of coronary atherosclerosis in patients with diabetes mellitus. |
| PubMedID- 24741462 | Letter: association between cardiac autonomic neuropathy, diabetic retinopathy and carotid atherosclerosis in patients with type 2 diabetes (endocrinol metab 2013;28:309-19, chan-hee jung et al.). |
| PubMedID- 23243415 | diabetes is associated with increased atherosclerosis, and diabetic patients have a 2–4-fold increased risk of cardiovascular mortality [1, 2]. |
| PubMedID- 22142413 | Second, excessive ldl trapping by hyperglycemia-induced ages may be associated with the accelerated development of atherosclerosis in patients with diabetes [11]. |
| PubMedID- 25806115 | It is critical to identify high-risk individuals for atherosclerosis among patients with type 2 diabetes because the burden for progression of arterial stiffness as shown by increased pwv is strongly associated with cardiovascular outcomes3031 as well as diabetic kidney disease.32 this study sheds light on the importance of evaluating visceral adiposity even in individuals with normal bmi among patients with type 2 diabetes. |
| PubMedID- 24656691 | Objective: controversies concerning the association of retinal microvascular abnormalities (rmas) with atherosclerosis in patients with diabetes exist. |
| PubMedID- 26445876 | In addition, a more recent study clearly revealed that subcutaneous adipose thickness assessed by ultrasonography is inversely associated with carotid atherosclerosis in patients with type 2 diabetes [17]. |
| PubMedID- 24282628 | In the last decades, the pandemic of overweight and obesity related to sedentary lifestyle and excess intake of refined foods has led to a dramatic rise in the prevalence of the metabolic syndrome and associated conditions, such as type 2 diabetes and dyslipidemia, leading to accelerated atherosclerosis [1], but also to nonalcoholic fatty liver disease (nafld) [2, 3]. |
| PubMedID- 20826281 | Objectives: to measure preclinical noninvasive markers of atherosclerosis in youth with type 1 diabetes (t1dm), and to determine their associations between physical activity level and cardiorespiratory fitness (maximal oxygen consumption [vo2max]). |
| PubMedID- 24797048 | The present study was designed to investigate the association of polymorphisms xbai (rs693) and ecori (rs1042031) of the apob gene with plasma apob level, lipid levels and the different ultrasound phenotypes of carotid atherosclerosis in patients with diabetes mellitus type 2. |
| PubMedID- 23324539 | In both the ketosis-onset and the non-ketotic diabetes, the prevalence of carotid atherosclerosis was markedly increased with age (both p<0.001) after controlling for sex, but no sex difference was observed (p=0.479 and p=0.707, respectively) after controlling for age. |