PedAM
Pediatric Disease Annotations & Medicines
| Disease | arteriosclerosis |
| Phenotype | |diabetes |
| Sentences | 200 |
| PubMedID- 20207378 | [usefulness of pulse oximetry in screening of carotid atherosclerosis in patients with type 2 diabetes mellitus]. |
| PubMedID- 26411567 | Vascular dysfunction caused by metabolic abnormalities in patients with diabetes is associated with accelerated atherosclerosis and increased risk of myocardial infarction (mi), stroke, and peripheral arterial disease. |
| PubMedID- 21996253 | Aims: to analyze the relationship between serum levels of osteocalcin and parameters of atherosclerosis in patients with type 2 diabetes mellitus (t2dm). |
| PubMedID- 24023518 | atherosclerosis in patients with diabetes is particularly aggressive, characterized by highercardiovascular event rates and a greater severity of coronary obstructive disease.13–16 cardiovascular disease represents the ultimate cause of death in approximately 75% ofpatients with diabetes.17 the periscope(pioglitazone effect on regression of intravascular sonographic coronary obstruction prospectiveevaluation) trial18 compared the effects of aninsulin sensitizer, pioglitazone, with an insulin secretagogue, glimepiride, on the progression ofcoronary atherosclerosis in patients with type 2 diabetes, and found that least squares meanpercentage atheroma volume increased 0.73% (95% confdence interval [ci]0.33%–1.12%) with glimepiride and decreased 0.16% (95% ci −0.57% to 0.25%) withpioglitazone (p = 0.002). |
| PubMedID- 23597082 | T2dm and cvd risk scores were estimated according to the formulae described in the diabetes risk formula of the atherosclerosis risk in communities (aric) study [21] and the systematic coronary risk evaluation (score) project, respectively [22]. |
| PubMedID- 23316958 | Indeed, substantial evidence suggests that chronic hyperglycemia plays a specific role in atherosclerosis progression in patients with diabetes [35]. |
| PubMedID- 22547909 | At the moment the reasons for the increased predisposition and progression of atherosclerosis in patients with diabetes are unknown. |
| PubMedID- 21226273 | atherosclerosis in diabetes begins earlier, is more markedly pronounced and progresses more rapidly. |
| PubMedID- 25712234 | Methods: 2,281 individuals in the multi-ethnic study of atherosclerosis without diabetes or hypertension, renal disease, or excess alcohol consumption underwent computed tomography (ct) for assessment of liver attenuation (marker of hepatic lipid content) and urinalysis (for albuminuria) at initial study visit, with assessment of incident and prevalent albuminuria by logistic regression in follow-up. |
| PubMedID- 21911774 | Dyslipidemia, one risk factor for atherosclerosis, frequently is associated with diabetes and increases the risk of cardiovascular disease (22). |
| PubMedID- 24719773 | atherosclerosis was associated with diabetes, hypertension, overweight (bmi 25–29.9), obesity (by bmi ≥ 30), and abdominal obesity when criteria of idf is used (men ≥ 90 cm; female ≥ 80 cm) and mainly with the presence of two or more risk factors (p < 0.001). |
| PubMedID- 21738343 | To verify the relationship between the mets score and coronary atherosclerosis in diabetes, we divided the study cohort into two groups based on the presence of diabetes. |
| PubMedID- 24943000 | Given the multi-faceted pathogenesis of atherosclerosis in diabetes, it is likely that any intervention to mitigate this risk must address cv risk factors beyond glycemia alone. |
| PubMedID- 21192815 | Right coronary wall cmr in asymptomatic older subjects showed increased coronary atherosclerosis in subjects with type 2 diabetes as well as coronary calcification. |
| PubMedID- 25537059 | Background: we aimed to investigate the association of toenail onychomycosis with subclinical atherosclerosis in patients with diabetes mellitus. |
| PubMedID- 20593206 | The objective of this study is to investigate the correlation of urinary albumin excretion rate (uaer) with the incidence of coronary heart disease (chd), pathological characteristics and severity of coronary atherosclerosis in patients with type 2 diabetes mellitus (t2dm), and explore the efficacy of using the urinary albumin excretion rate (uaer) to predict the risk of chd in patients with t2dm. |
| PubMedID- 21605345 | Diabetic cardiomyopathy is a clinical condition diagnosed when ventricular dysfunction develops in patients with diabetes devoid of coronary atherosclerosis and hypertension. |
| PubMedID- 20004424 | We investigated the relationship between hemoglobin concentration and various factors as well as markers of subclinical atherosclerosis in men with type 2 diabetes mellitus. |
| PubMedID- 20516379 | The phosphodiesterase inhibitor cilostazol induces regression of carotid atherosclerosis in subjects with type 2 diabetes mellitus: principal results of the diabetic atherosclerosis prevention by cilostazol (dapc) study: a randomized trial. |
| PubMedID- 26177483 | Glucagon-like peptide-1 (glp-1) receptor agonists are a class of injective anti-diabetic drugs that improve glycemic control and many other atherosclerosis-related parameters in patients with type 2 diabetes (t2d). |
| PubMedID- 23230750 | Conclusion: glucose excursions may contribute to the development of atherosclerosis in patients with type 2 diabetes, which is independent from hba1c levels. |
| PubMedID- 23589729 | Hypertension may be a factor in whether or not aspirin is effective; in the japanese prevention of atherosclerosis with angina in diabetes (j-pad) study, patients who attained significant lowering of their blood pressure were more responsive to aspirin than those who did not. |
| PubMedID- 22013385 | Hence, such situations aggravate vascular endothelial dysfunction and atherosclerosis in diabetes [10, 11]. |
| PubMedID- 21483695 | Part of the increased susceptibility to atherosclerosis of patients with type 2 diabetes mellitus and the metabolic syndrome has been attributed to the decreased clearance of trps [5], [31], [32]. |
| PubMedID- 22483261 | Type 2 diabetes and the progression of visualized atherosclerosis to clinical cardiovascular events. |
| PubMedID- 20191077 | This article reviews the pathophysiology of atherosclerosis in diabetes, the role that tzds play in this process and the imaging trials looking at the progression or regression of atherosclerosis in patients treated with tzds. |
| PubMedID- 22576258 | The pathophysiology of atherosclerosis development in patients with diabetes mellitus (dm) is similar to that in nondiabetics. |
| PubMedID- 26557013 | atherosclerosis is strongly associated with hypercholesterolaemia, hypertension, diabetes, smoking and genetic factors. |
| PubMedID- 23922510 | In addition to microvascular changes, such as nephropathy, retinopathy and neuropathy, diabetes leads to atherosclerosis or macrovascular changes. |
| PubMedID- 26505665 | Method: this case-control study included 596 type 2 diabetes mellitus patients with carotid atherosclerosis and 379 patients without carotid atherosclerosis. |
| PubMedID- 22148131 | The risk factors for atherosclerosis including diabetes mellitus hypertension, hyperlipidemia and smoking were not determined in his past medical history and laboratory analysis. |
| PubMedID- 21403831 | Several models are available to study atherosclerosis and cardiomyopathy associated with diabetes, including apoe−/− and ldlr −/− mice in which type 1 diabetes is induced by streptozotocin or viral injection [33, 34]. |
| PubMedID- 22748110 | Hyperglycemia plays a specific role in atherosclerosis progression in patients with diabetes and igt[17]. |
| PubMedID- 24295032 | Disturbances in the autonomic system modulation seem to precede the increase in the thickness of the carotid intima, a predictor of atherosclerosis progression in patients with type 2 diabetes [6,7]. |
| PubMedID- 24130360 | Cacti was designed to examine the prevalence of subclinical atherosclerosis in adults with type 1 diabetes and a comparable group of controls without any diabetes. |
| PubMedID- 21525447 | Recently, results of the japanese primary prevention of atherosclerosis with aspirin for diabetes trial showed that, after a median follow-up of 4.37 years, aspirin therapy was associated with a (nonsignificant) 20% reduction (hazard ratio 0.80 [95% ci 0.58–1.10]) in the risk of the primary composite end point, including fatal or nonfatal ischemic heart disease, fatal or nonfatal stroke, transient ischemic attack, and peripheral arterial disease (12). |
| PubMedID- 24799979 | Instead, traditional cvd risk factors, age, gender, obesity, and diabetes, were significant determinants of subclinical atherosclerosis, accounting for 29.2% of cimt variability. |
| PubMedID- 24396666 | One recent study showed that glucose variability for 72 hours measured by a continuous glucose monitoring system was associated with coronary atherosclerosis in patients with type 2 diabetes [17]. |
| PubMedID- 26269391 | Background: diabetes is associated with aggressive atherosclerosis, leading to an increased risk of in-stent restenosis and stent thrombosis. |
| PubMedID- 25120969 | Effect of age and blood pressure on surrogate markers of atherosclerosis in patients with type 2 diabetes mellitus. |
| PubMedID- 22827403 | The aim of our study was to evaluate serum amyloid a (saa), an acute phase reactant, and carotid intima-media thickness (cimt) as a valid predictor of atherosclerosis in women with gestational diabetes mellitus (gdm). |
| PubMedID- 20302618 | Varghese performed a randomized, placebo-controlled, double-blind study to evaluate the effect of rosiglitazone treatment on carotid atherosclerosis in subjects with type 2 diabetes with a primary endpoint of the change from baseline in carotid arterial wall volume, reflecting plaque burden, as measured by cmr [66]. |
| PubMedID- 21387659 | [series, clinical study from japan and its reflections; japanese primary prevention of atherosclerosis with aspirin for diabetes (jpad) trial]. |
| PubMedID- 21779189 | Leptin and adiponectin can be more relevant to atherosclerosis in subjects with obesity and diabetes mellitus than conventional atherosclerotic factors such as bp and lipid levels [7, 14, 15]. |
| PubMedID- 21658276 | Stimuli known to accelerate atherosclerosis in diabetes, such as oxidized ldls[26], ages[19], hypoxia[27]could role as antigens to induce dcs to adhesion to and transmigration through endothelial cells. |
| PubMedID- 23570342 | Another new marker that deserves our attention is the uric acid; although uric acid can act as an antioxidant, excess serum accumulation is often associated with several conditions, and has been suggested as an independent risk factor for carotid atherosclerosis in patients with type 2 diabetes [25]. |
| PubMedID- 21981808 | The high risk of atherosclerosis in diabetes is mainly attributed to endothelial dysfunction that results both from endothelial cell damage and impaired endothelial repair [29]. |
| PubMedID- 20005514 | Wide postchallenge glucose excursions may contribute to the development of atherosclerosis in individuals with type 2 diabetes, independent of other risk factors. |
| PubMedID- 25509887 | Aim: to study the prognostic value of multifocal atherosclerosis (mfa) in patients with diabetes mellitus (dm) at high risk for myocardial ischemia who need coronary angiography (cag). |
| PubMedID- 23724401 | Vitamin d deficiency has been to be associated with cvd risk factors such as hypertension and diabetes mellitus, with markers of subclinical atherosclerosis such as intima-media thickness and coronary calcification as well as with cardiovascular events such as myocardial infarction, stroke and congestive heart failure. |