PedAM
Pediatric Disease Annotations & Medicines
| Disease | asthma |
| Symptom | C0028754|obesity |
| Sentences | 104 |
| PubMedID- 24809015 | Many clinical studies showed the consistent association of obesity with asthma in terms of causal relationship, dose-dependency, and reversal of asthma by intervention, although the precise mechanism between obesity and asthma remains unclear . |
| PubMedID- 26442312 | Treatment of patients with bronchial asthma associated with obesity in a health resort "okeanskiy". |
| PubMedID- 22931550 | obesity has been associated with asthma . |
| PubMedID- 24182891 | Prevalence of obesity in asthma and its relations with asthma severity and control. |
| PubMedID- 24274607 | Conclusions: our study found an increased prevalence of obesity in children with asthma, with a predominance in male gender, and showed a high association between the severity of asthma and increased bmi. |
| PubMedID- 22133422 | obesity was not associated with asthma severity. |
| PubMedID- 23297741 | It is possible that obesity is truly associated with atopic asthma but our data had a low statistical power to detect such an association. |
| PubMedID- 22379605 | Conclusions: obesity leads to more severe asthma symptoms in children. |
| PubMedID- 23692648 | Furthermore, obesity is associated with less asthma control and more use of oral corticosteroids . |
| PubMedID- 25638180 | Results: after adjusting for confounding factors, maternal smoking during pregnancy, preterm birth and obesity were significantly associated with persistent asthma, with adjusted ors (95% ci) of 2.11 (1.08- 4.13), 2.61(1.07-6.35) and 2.89 (1.49-5.61), respectively. |
| PubMedID- 24548172 | Gender-specific differences in associations of overweight and obesity with asthma and asthma-related symptoms in 30 056 children: result from 25 districts of northeastern china. |
| PubMedID- 25914932 | This article will discuss what we have learned about the immunological and pathophysiological basis of asthma in obesity from animal and human studies, and how this might guide therapy. |
| PubMedID- 23277874 | This retrospective analysis of data obtained from the 4th knhanes, a nationwide survey of south korea in 2008, showed that arthritis, rhinitis, depression and obesity were independently associated with both self-reported ever-asthma and wheezing in adults ≥ 40 years old. |
| PubMedID- 21555716 | An interaction between the associations of bmi and fat mass and obesity-associated (fto) genotype with asthma explained the different directions of the different estimates, and a simulation study supported the observation that msmm/mgmm estimators are negatively correlated with the other estimators when such an interaction is present. |
| PubMedID- 24821412 | Rationale: the pathogenesis of asthma in obesity is poorly understood, but may be related to breathing at low lung volumes. |
| PubMedID- 23420493 | They have been implicated in lipid digestion and obesity, activation of immune cells, asthma, atherosclerosis, acute respiratory distress syndrome and host defense against bacteria, viruses and parasites (5–8). |
| PubMedID- 24899788 | As osas and asthma are highly associated with obesity, inflammation, and lung injury, this may suggest the association of omentin and lung injury. |
| PubMedID- 24454412 | The possibility that asthma may lead to obesity is less controversial, because of fear of exercise or inability to exercise regularly. |
| PubMedID- 24336249 | In summary, we showed in a mouse model of asthma associated with obesity that ahr develops through a pathway involving nlrp3, il-1β and pulmonary il-17+ ilc3 cells. |
| PubMedID- 20456316 | obesity was positively associated with asthma overall (odds ratio or for obese vs normal bmi = 2.28, 95% ci: 1.76, 2.96; or for obese vs normal waist circumference = 1.75; 95% ci: 1.22, 2.51) but insulin resistance was not (or = 1.26; 95% ci: 0.80, 1.98). |
| PubMedID- 23010231 | Conclusion: given the differences between areas and the associations between environmental risk factors and obesity with asthma and wheeze, the study findings support environment and health risk behavior explanations for the observed geographic variations. |
| PubMedID- 21415135 | Background: it is unclear why obesity is associated with worse asthma control. |
| PubMedID- 22092883 | Class ii/iii obesity was associated with increased asthma exacerbations requiring oral corticosteroids (repeated measures logistic regression, or: 1.13, 95% ci: 1.03-1.25; p = 0.01) and increased requirement of inhaled corticosteroid for long-term asthma management (or: 1.45, 95% ci: 1.29-1.62; p < 0.0001). |
| PubMedID- 23355113 | Background: obesity is associated with poor asthma outcomes; weight loss improves such outcomes. |
| PubMedID- 20701611 | Objective: the aim of this study was to investigate whether differences in high-sensitivity c-reactive protein (hs-crp) levels explain why obesity is associated with asthma in females but not in males. |
| PubMedID- 25191399 | In summary, it appears that obesity is significantly associated with a greater asthma severity and a poorer asthma control and quality of life. |
| PubMedID- 22726248 | Several studies have associated obesity with asthma particularly central obesity which is an important component of metabolic syndrome. |
| PubMedID- 26441284 | Second, obesity was not associated with the asthma prevalence in boys or girls. |
| PubMedID- 23176705 | Finally, studies have demonstrated that obesity was associated with poor asthma control and poor response to ics treatment . |
| PubMedID- 24947900 | asthmatics with obesity and those with symptoms of depression both had a higher risk of having poorly controlled asthma (adjusted odds ratio of 1.83 ci 1.23-3.52 for obesity, and 2.08 ci 1.23-3.52 for depression), but there was no interaction between the two. |
| PubMedID- 22926907 | Bronchial asthma in obesity--a distinct phenotype of asthma. |
| PubMedID- 22609068 | obesity is associated with poor asthma control, but the reason for this is unclear. |
| PubMedID- 23619597 | The treatment of asthma in obesity can be challenging, as obesity is associated with poor response to standard controller medications. |
| PubMedID- 25975622 | Conclusions: elevated bmi, particularly obesity, is associated with subsequent poor asthma control, especially in the risk domain (exacerbations). |
| PubMedID- 23258582 | In conclusion, overweight and obesity is associated with poorer asthma control and, very importantly, overall poorer response to asthma therapy, compared with normal weight individuals. |
| PubMedID- 22375278 | A number of studies have linked obesity with asthma in adults and children. |
| PubMedID- 23311506 | We assessed the independent association of these snps and obesity with asthma prevalence and incidence. |
| PubMedID- 24807420 | These conditions are influenced by genetic and environmental factors, and several studies have found obesity to be associated with asthma in both adult and paediatric populations . |
| PubMedID- 21944975 | Major conclusions: obesity is associated with poor asthma control, altered responsiveness to medications and increased morbidity. |
| PubMedID- 21773007 | Measures of obesity associated with asthma diagnosis in ethnic minority children. |
| PubMedID- 22788947 | Treatment of asthma in obesity needs to consider altered response to controller therapy, and the fact that mechanical factors, metabolic inflammation and other comorbidities are probably contributing to airway disease. |
| PubMedID- 23661915 | obesity with asthma has thus emerged as a separate phenotype of asthma. |
| PubMedID- PMC4407108 | By presenting our two cases we would like put a stress on the variety features inside the group of patients with asthma associated with obesity or overweight. |
| PubMedID- 26542296 | Adipokines may change the t helper cell balance in favor of a t helper cell type 1 (th1) response, as it is seen in asthma associated with obesity . |
| PubMedID- 25635872 | As both fetal growth and childhood obesity is associated with asthma, further information regarding the associations of peak weight and height velocity with respiratory disorders seems valuable. |
| PubMedID- 23215875 | Objective: the potential role of central obesity in asthma outcomes has been examined in a few studies. |
| PubMedID- 21999468 | obesity was also associated with increased atopic asthma (aor 1.98, 95% ci 1.47-2.66, p<0.0001), but not associated with nonatopic asthma (p=0.20), atopic or nonatopic rhinoconjunctivitis (p=0.08 and 0.31, respectively), food allergies (p=0.67 and 0.35, respectively) or atopy (p=0.40). |
| PubMedID- 20334686 | On a population basis, the high prevalence of obesity among adults with asthma suggests an important opportunity to improve the lives of many such individuals. |
| PubMedID- 23970905 | There is also some evidence to suggest that obesity may reduce threshold of ahr to potential asthma triggers. |
| PubMedID- 21151697 | To date studies of obesity in asthma have focussed upon the body mass index (bmi), although a criticism of the bmi is that it does not take into account body composition. |