PedAM
Pediatric Disease Annotations & Medicines
| Disease | epilepsy |
| Symptom | |seizures |
| Sentences | 329 |
| PubMedID- 23311867 | Altered sleep regulation in a mouse model of scn1a-derived genetic epilepsy with febrile seizures plus (gefs+). |
| PubMedID- 23851401 | Fourth, to aid in the early detection and treatment of seizures in patients with intractable epilepsy i.e. |
| PubMedID- 24910743 | The outcome of seizures in children with refractory epilepsy has been improved by new-generation antiepileptic drugs5. |
| PubMedID- 24864167 | Background: in addition to recurrent epileptic seizures, children with epilepsy can have coexisting cognitive and behavioral difficulties but the spectrum and prevalence of such difficulties are uncertain. |
| PubMedID- 23269021 | On the other hand, seizures as consequence of idiopathic epilepsy are the most common brain disease in dogs. |
| PubMedID- 22471526 | Over 800 mutations have been identified in the voltage-gated sodium channel genes scn1a and scn2a in human epilepsies, including genetic epilepsy with febrile seizures plus (gefs+) and dravet syndrome. |
| PubMedID- 24220630 | In this study, scn2aq54 heterozygotes exhibited adult-onset, progressive epilepsy that begins with partial seizures of short duration of hippocampal origin. |
| PubMedID- 25667832 | A 35-year-old man had a 7-year history of seizures with no definitive epilepsy risk factor. |
| PubMedID- 25564312 | Purpose: to assess if absence seizures (ass) occur in patients with myoclonic epilepsy of infancy (mei). |
| PubMedID- 24961619 | Some investigators considered epilepsy rare in patients with psychogenic seizures whereas others found nonepileptic seizures and epilepsy, per se, to co-occur in 12%–42% of patients making these discriminations difficult. |
| PubMedID- 22147072 | Genetic epilepsy with febrile seizures plus: definite and borderline phenotypes. |
| PubMedID- 23662118 | Despite substantial evidence from animal research in support of antiepileptic effects of acupuncture, a large number of clinical studies have also shown that patients have benefited from acupuncture for control of their seizures, especially in cases with refractory epilepsy , though results from some studies beg to differ . |
| PubMedID- 22529421 | We conclude that tramadol may provoke seizures in patients with epilepsy even within the recommended dose range. |
| PubMedID- 20856605 | Holmes et al described 21 patients who had previous epilepsy surgery with recurrence of seizures, most of whom required extension of previous resections.8 currently the tendency in all epilepsy centers is to perform more selective resections or less aggressive procedures in order to spare other mental functions in patients. |
| PubMedID- 21739107 | Her ndph and seizures ceased with epilepsy treatment. |
| PubMedID- 26369628 | One, who had epilepsy of infancy with migrating focal seizures, had 80% reduction in seizure frequency. |
| PubMedID- 21245982 | Previous studies have reported that mhc class i and class ii antigens are expressed in the hippocampi of epileptic patients . |
| PubMedID- 26071927 | Two patients developed chronic epilepsy, with seizures occurring later than one year after the pres. |
| PubMedID- 21147388 | During postoperative follow-up, careful documentation of breakthrough seizures due to benign focal epilepsy of childhood is important, so that these patients are not labeled as surgical failures. |
| PubMedID- 25540729 | Patients were dichotomized into two categories: those affected by epilepsy with generalized tonic-clonic seizures vs those having epilepsy with partial seizures. |
| PubMedID- 25735907 | Conclusion: generalized eeg discharges in patients with febrile seizures are not predictive of later epilepsy, but focal discharges are. |
| PubMedID- 20135212 | The recurrent, unprovoked seizures associated with epilepsy can have a devastating effect on those with this disorder. |
| PubMedID- 26011637 | Mesial temporal lobe epilepsy with childhood febrile seizures (fs-mtle) is a distinctive entity that can be delineated from afebrile mtle as demonstrated by epidemiological , and genomic studies. |
| PubMedID- 23445821 | The small proportion of epilepsy patients with prolonged seizures is diagnosed only with their chronic epilepsy diagnosis number. |
| PubMedID- 22141347 | Lacosamide is indicated for use as adjuvant treatment of focal-onset seizures in patients with epilepsy, and there is some evidence that it may also be of use in patients with status epilepticus and cancer patients with epilepsy. |
| PubMedID- 25549873 | The pilocarpine rat model, in which status epilepticus (se) leads to epilepsy with spontaneous recurrent seizures (srs), is widely used to study the mechanisms of epileptogenesis and develop strategies for epilepsy prevention. |
| PubMedID- 21488712 | Objective: this study aims to compute the budget impact of lacosamide, a new adjunctive therapy for partial-onset seizures in epilepsy patients from 16 years of age who are uncontrolled and having previously used at least three anti-epileptic drugs from a belgian healthcare payer perspective. |
| PubMedID- 23365482 | The present report describes a patient who had been diagnosed and treated as having epilepsy with medically-refractory seizures for 16 years. |
| PubMedID- 20580620 | Accurate evaluation of status epilepticus or clusters of seizures in patients with epilepsy is a critical issue in epilepsy care units. |
| PubMedID- 25835811 | The proband’s daughter (ii-3) was also affected by generalized epilepsy with absence seizures, which could be caused by the ryr2 exon 3 deletion. |
| PubMedID- 21224219 | The hippocampus is one of the main plasticity engines in the brain, and is also a structure frequently implicated in the generation of epileptic seizures, with temporal lobe epilepsy constituting the most prevalent form of epilepsy in the adult population. |
| PubMedID- 22457654 | Specifically, mutations in the nav1.1 alpha subunit gene (scn1a) are responsible for “generalized epilepsy with febrile seizures plus” (gefs+; scheffer and berkovic, 1997) and dravet’s syndrome (mantegazza et al., 2010; meisler et al., 2010). |
| PubMedID- 20957120 | All these findings taken together clearly suggest that advantages from an appropriate treatment of seizures in people with epilepsy clearly overcome potential disadvantages, making aeds potentially protective agents against suicide. |
| PubMedID- 22011963 | Purpose: mutation analysis of the scn1b, scn1a and gabrg2 genes in children affected by genetic (generalised) epilepsy with febrile seizures plus (gefs(+)) and their affected and some unaffected family members, coming from a restricted geographic area, was performed. |
| PubMedID- 24138934 | Stress is known to trigger seizures in patients with epilepsy, highlighting the physiological stress response as a possible therapeutic target for epilepsy treatment. |
| PubMedID- 25127174 | Available treatments do not fully control seizures in a third of patients with epilepsy, and produce substantial side-effects. |
| PubMedID- 25167889 | Lacosamide (lcm) is a functionalized amino acid specifically developed for use as an antiepileptic drug (aed) and is currently indicated as adjunctive treatment for partial-onset seizures in adults with focal epilepsy (maximum approved dose 400 mg/day). |
| PubMedID- 21843600 | A novel scn1a missense mutation causes generalized epilepsy with febrile seizures plus in a chinese family. |
| PubMedID- 24014518 | It bears the largest number of known epilepsy-related mutations, some associated with febrile seizures (oliva et al., 2012). |
| PubMedID- 23032136 | In univariable analysis, active epilepsy with tonic-clonic seizures at admission was significantly associated with increased participation in employment or education at follow-up, so was decreased frequency of tonic-clonic seizures from admission to follow-up. |
| PubMedID- 25965391 | Dravet syndrome (ds) is a devastating form of childhood epilepsy that begins with prolonged seizures in the first year of life. |
| PubMedID- 26489091 | The aim of the present study was to partially characterize the evolution of the functional network during the preictal-ictal transition in partial seizures in patients with temporal lobe epilepsy (tle). |
| PubMedID- 24727311 | Methods: prospective testing during partial seizures was performed in patients with epilepsy using the responsiveness in epilepsy scale (n = 83 partial seizures, 30 patients). |
| PubMedID- 23970964 | epilepsy of infancy with migrating focal seizures, is a rare, age-specific epileptic encephalopathy with a malignant course with onset in the first 6 months of age. |
| PubMedID- 25206590 | The present study demonstrated that when gastrodine was combined with antiepileptic drugs, epileptic seizures in patients with focal epilepsy could be controlled, and gastrodine induced repair of abnormal perfusion foci as well as potentiating antiepileptic drug effects. |
| PubMedID- 22976060 | Finally, there are times when epileptic seizures resemble one of the epilepsy mimics. |
| PubMedID- 22533250 | Nowadays it is well presumed that the writer could have had temporal lobe epilepsy with secondary generalized seizures, the symptoms of which he by no means was producing throughout his life. |
| PubMedID- 26308341 | It has been shown that natural cyclic fluctuations of p4 and e2 during the menstrual cycle could influence exacerbation of seizures in women with epilepsy . |
| PubMedID- 21248271 | Missense mutations occurred most frequently in the voltage and ion-pore regions where changes in amino acid polarity were greater in the dravet group compared to the genetic epilepsy with febrile seizures plus group (3.6 vs 2.7; p = 0.031). |
| PubMedID- 20548952 | Approximately 60% of the sca10 patients also suffer from epilepsy with complex partial seizures and generalized tonic-clonic seizures, which become life-threatening due to development of status epilepticus . |