PedAM
Pediatric Disease Annotations & Medicines
| Disease | epilepsy |
| Symptom | |seizures |
| Sentences | 329 |
| PubMedID- 26140313 | Kcnt1 mutations have been found in epilepsy of infancy with migrating focal seizures (eimfs; also known as migrating partial seizures in infancy), autosomal dominant nocturnal frontal lobe epilepsy, and other types of early onset epileptic encephalopathies (eoees). |
| PubMedID- 22000954 | Purpose: ring chromosome 20 {r(20)}--manifests as a refractory epilepsy syndrome with complex partial seizures (cps), nocturnal frontal lobe seizures and non-convulsive status epilepticus (ncse) in the majority of cases. |
| PubMedID- 25914447 | Abbreviations: aeds - antiepileptic drugs, blast - basic local alignment search tool, cbz - carbamazepine, gefs+ - generalized epilepsy with febrile seizures plus, gpcr - g protein coupled receptor, nav - sodium channel with specific voltage conduction, pdb - protein data bank, pht - phenytoin, pir - protein information resources, saves - structural analysis and verification server, vgsc - voltage-gated sodium channels. |
| PubMedID- 23928193 | In total, we reviewed 491 seizures: 277 seizures in patients with temporal lobe epilepsy (tle) associated with hippocampal sclerosis (tle-hs group) and 214 in tle caused by other lesions (tle-oth group). |
| PubMedID- 25661285 | Objective: hyperventilation induces absence seizures in children with absence epilepsy, and routine electroencephalography studies include three minutes of hyperventilation. |
| PubMedID- 22525008 | Generalized epilepsy with febrile seizures plus (gefs+) and severe myoclonic epilepsy of infancy (smei) differ in their clinical severity and prognosis even though mutations of the na(v) 1.1 sodium channel are responsible for both disorders. |
| PubMedID- 23323131 | Automotor seizures are typical of temporal lobe epilepsy but occasionally can also be seen with frontal lobe seizures. |
| PubMedID- 26509114 | Despite the focality of cts and rolandic seizures in patients with benign epilepsy, there is growing evidence from neuroimaging studies reporting memory, language, attention, auditory and cognitive impairments in bects patients that bects may functionally and structurally affect a larger portion of the brain at rest (bocquillon et al., 2009; cataldi et al., 2013; lopes et al., 2014; northcott et al., 2007; verrotti et al., 2014). |
| PubMedID- 26554554 | He developed epilepsy with generalized tonic-clonic seizures at 12 months, which is currently under control on phenytoin. |
| PubMedID- 24282673 | )-induced seizures, quantified expression levels of several epilepsy-related genes (fos, casp 3, ccl3, ccl4, npy, arc, penk, camk2a, bdnf and egr1) by qpcr using hippocampal, neocortical and prefrontal cortical tissue samples before examining correlations between expression changes and seizure severity. |
| PubMedID- 24778885 | Schindler and his colleagues find that the correlation of multichannel eeg either remains approximately unchanged or decreases during the first half of the seizures in patients with pharmacoresistant focal epilepsy . |
| PubMedID- 20722665 | Recent evidence has suggested possible genetic links to the gefs+ (generalized epilepsy with febrile seizures plus) family, and, additionally, some children with structural brain lesions can mimic the doose syndrome phenotype. |
| PubMedID- 20237798 | The only known β1 mutation causes generalized epilepsy with febrile seizures plus for which skeletal muscle dysfunction has not been described . |
| PubMedID- 24024028 | There is no known cause of mae identified although there may be a possible genetic link to the generalized epilepsy with febrile seizures plus (gefs+) family . |
| PubMedID- 26333769 | epilepsy of infancy with migrating focal seizures (eimfs) is an early-infantile epileptic encephalopathy (eiee) previously known as migrating partial seizures of infancy. |
| PubMedID- 22007171 | Mutation sites responsible for causing genetic epilepsy with febrile seizures plus (gefs + 1), temporal lobe epilepsy (tle), and dravet syndrome are located in the extracellular immunoglobulin loop (meadows et al., 2002; wallace et al., 2002; audenaert et al., 2003; scheffer et al., 2007; patino et al., 2009). |
| PubMedID- 23256267 | Recurrent seizures in pregnancy-epilepsy or eclampsia: a diagnostic dilemma. |
| PubMedID- 22957238 | Drawn to these findings, sir horsley was likely the first to attempt amelioration of epilepsy in a patient with posttraumatic seizures via a craniotomy 4. |
| PubMedID- 23349592 | The clinical manifestations of seizures, causes of epilepsy, and choice of anti-epileptic drugs (aeds) are different in elderly people with epilepsy compared to the young. |
| PubMedID- 23180096 | We show that in pilocarpine-challenged mice developing epilepsy with recurrent seizures after a latent period of 2 weeks, hippocampal leptin receptor (obr) immunofluorescence was increased at 6 weeks. |
| PubMedID- 20345938 | In one patient, we diagnosed a focal epilepsy with seizures occurring in cluster. |
| PubMedID- 23032131 | Scn1a is a gene that codes for the voltage-dependent sodium channel alpha1 subunit and has been implicated in generalized epilepsy with febrile seizures plus and severe myoclonic epilepsy in infancy. |
| PubMedID- 26513359 | To this end, we compare the dynamics of the qeeg measures x immediately before, during and directly after seizures in patients with focal epilepsy syndromes. |
| PubMedID- 22883631 | Results: two hundred and ninety-one cases of active epilepsy, all with convulsive seizures, were identified. |
| PubMedID- 21731658 | In one example, the disease family “generalized epilepsy with febrile seizures plus” obtains little information from the ppi network. |
| PubMedID- 21040232 | Methods: a microsatellite marker analysis was performed on the known fs and generalized epilepsy with febrile seizures plus (gefs+) loci. |
| PubMedID- 23364654 | Sudden unexplained death in epilepsy (sudep) is associated with generalized tonic-clonic seizures and occurs most often when patients are in bed. |
| PubMedID- 20410126 | Several missense mutations of the na(v)1.1 channel (scn1a), which alter channel properties, have been reported in a familial syndrome of gefs+ (generalized epilepsy with febrile seizures plus). |
| PubMedID- 20522430 | Background mutations in scn1a can cause genetic epilepsy with febrile seizures plus (gefs+, inherited missense mutations) or dravet syndrome (ds, de novo mutations of all types). |
| PubMedID- 21719429 | D = (scn1a protein) domain; genetic epilepsy with febrile seizures plus = genetic epilepsy with febrile seizures plus; s = (scn1a protein) segment. |
| PubMedID- 24790647 | Clobazam appears to have a safe profile and sustained effectiveness over the first 3 years of use in lgs and other epilepsy syndromes with intractable seizures, which makes it a viable long-term treatment option. |
| PubMedID- 26379618 | Surgical intervention is the treatment of choice for controlling seizures in patients with epilepsy refractory to medication. |
| PubMedID- 20933440 | Patient and methods: we present a case of focal criptogenetic epilepsy with speech arrest seizures and bilateral synchronous spike and wave scalp eeg pattern (secondary bilateral synchrony). |
| PubMedID- 22998946 | The idiopathic generalized epilepsy, characterized with typical absence seizures, has been assumed to be a type of benign epilepsies. |
| PubMedID- 21194458 | Actually, clinicians follow general guidelines for the acute therapeutic management of seizures in patients with both epilepsy and brain tumours, including intravenous benzodiazepines, valproic acid, and levetiracetam, followed by phenytoin and then barbiturate if necessary . |
| PubMedID- 24172878 | epilepsy poses challenges because of uncontrolled seizures, treatment complexity, social disadvantages (e.g., unemployment), and stigma. |
| PubMedID- 26244497 | Electroencephalogram (eeg) is a non-invasive measurement that provides temporal and spatial information regarding the electrical activity of the brain that has been widely used to detect seizures in patients with epilepsy 3. |
| PubMedID- 26288758 | A 19-year-old right-handed man had attention deficit disorder and treatment-resistant focal epilepsy with weekly seizures (behavioral arrest, incomprehensible speech, and postictal confusion) since the age of nine. |
| PubMedID- 25667824 | This case report emphasizes the importance of ongoing rational therapy changes when seizures in patients with epilepsy are treated unsatisfactorily. |
| PubMedID- 22425777 | The first described beta1 subunit mutation is the c121w, that is related to generalized epilepsy with febrile seizures plus (gefs+), a childhood genetic epilepsy syndrome. |
| PubMedID- 23914154 | Estradiol has been known to play a role in the exacerbation of seizures in women with epilepsy (logothetis et al., 1959; bäckström, 1976; jacono and robinson, 1987). |
| PubMedID- 22379786 | Effect of electroacupuncture of different regions of the auricle on epileptic seizures in epilepsy rats. |
| PubMedID- 23420672 | For example, in mouse models of familial alzheimer's disease, it has been suggested that nav1.1 sodium channels are reduced at the cell surface of gabaergic basket cells of the dg, leading to disinhibition of granule cells; in some genetic forms of epilepsy (generalized epilepsy with febrile seizures-plus; severe myoclonic epilepsy in infancy), mutations in nav1.1 cause the disease (catterall et al., 2010; scharfman, 2012b; verret et al., 2012). |
| PubMedID- 24148888 | To determine the status of white matter following cessation of seizures, participants with epilepsy were classified as active versus remitted and comparisons included: (1) controls versus all children with epilepsy, (2) controls versus children with remitted seizures, (3) controls versus children with active seizures, and (4) children with active versus remitted epilepsy. |
| PubMedID- 23742147 | Another clinical case study example is the repurposing of gabapentin, an fda-approved drug for controlling seizures in patients with epilepsy, to treat patients with tinnitus, as shown in sentence: “gabapentin for the treatment of tinnitus: a case report” (pmid 11233342). |
| PubMedID- 24355397 | Scn1a mutations have been associated to a number of neurological disorders, including generalized epilepsy with febrile seizures plus, dravet syndrome, borderline myoclonic epilepsy in infancy, intractable childhood epilepsy with generalized tonic-clonic seizures, familial hemiplegic migraine, and a number of cryptogenic focal and generalized epilepsies. |
| PubMedID- 21442966 | epilepsy with generalized seizures was found in majority of patients from examined group. |
| PubMedID- 23936641 | These include ohtahara syndrome, early myoclonic encephalopathy, epilepsy of infancy with migrating focal seizures, west syndrome, dravet syndrome, lennox-gastaut syndrome, epilepsy with myoclonic atonic seizures, and landau-kleffner syndrome. |
| PubMedID- 21488303 | Disease: generalized epilepsy with febrile seizures plus. |
| PubMedID- 23093905 | In most cases, epilepsy, including epilepsy with partialonset seizures, is idiopathic, that is, cause unknown. |