PedAM
Pediatric Disease Annotations & Medicines
| Disease | epilepsy |
| Symptom | |seizures |
| Sentences | 329 |
| PubMedID- 23951148 | The increase in extracellular glutamate in the hippocampus may trigger spontaneous seizures in patients with complex partial epilepsy . |
| PubMedID- 23806632 | Purpose: little is known about the triggering factors (tfs) of seizures in persons with epilepsy (pwe). |
| PubMedID- 23555229 | Zonisamide is a sulfonamide anticonvulsant approved for using as an adjunctive treatment of partial seizures in adults with epilepsy by blocking sodium and calcium channels, which leads to the suppression of neuronal hypersynchronization (i.e. |
| PubMedID- 25729654 | Other causes are neurologic, sometimes resulting in seizures in patients with epilepsy and head trauma. |
| PubMedID- 20618407 | Bearing some similarities in triggering factor and manifestations of the seizures in patients with eating-evoked epilepsy, seizures in fasted animals may provide insight into the mechanism(s) of this rare and partially controlled form of reflex epilepsy. |
| PubMedID- 22770914 | People who were reported to have seizures were interviewed with an epilepsy-specific questionnaire11 and those who were classed as positive were invited to be assessed by a clinician. |
| PubMedID- 22247871 | this has recently been approved for the treatment of partial seizures in patients with epilepsy and for the treatment of neuropathic pain, in europe. |
| PubMedID- 25455727 | We investigated inflammatory markers to determine the chronic inflammatory process underlying the pathophysiology of intractable epilepsy presenting with frequent motor seizures in children. |
| PubMedID- 20301601 | epilepsy with generalized tonic-clonic seizures and/or complex-partial seizures typically appears around age ten years. |
| PubMedID- 20153261 | Ictal behavior coupled with spect findings during 28 seizures in patients with temporal lobe epilepsy (tle) with unilateral hippocampal sclerosis (13 left; 15 right) was displayed as flowcharts from right-sided (rtle) plus left-sided (ltle) seizures. |
| PubMedID- 24358150 | Here we report on abolished expression of α2δ-2 in a patient, offspring to consanguineous parents characterized by the association of epilepsy with also absence seizures, dyskinetic movements and cerebellar atrophy, a clinical picture closely resembling the phenotype displayed by the ducky mouse. |
| PubMedID- 23945787 | Genetic epilepsy with febrile seizures plus (gefs(+)) is an inherited epilepsy that can result from mutations in at least four ion channel subunits. |
| PubMedID- 25107880 | There were higher twin concordance estimates for monozygotic (mz) than for dizygotic (dz) twins for idiopathic generalized epilepsies (mz = 0.77; dz = 0.35), genetic epilepsy with febrile seizures plus (mz = 0.85; dz = 0.25), and focal epilepsies (mz = 0.40; dz = 0.03). |
| PubMedID- 24891901 | 8 it is true that epilepsy with the absence seizures is among those most frequently described in glut1 deficiency syndrome, but more often it has an early onset (before the age of 4), while in the forms with later onset, as in our patient, the combination of drug-resistant absence seizures (without other types of seizures) and mental retardation, present in the case we have reported, has not been described. |
| PubMedID- 24269665 | The findings offer some support to the theory that alf is associated with uncontrolled seizures and that elimination of seizures via epilepsy surgery may improve retention by providing a stable environment for "slow" consolidation to occur. |
| PubMedID- 21645995 | We have identified an epilepsy syndrome with temporal lobe seizures commonly evolving to generalised convulsions. |
| PubMedID- 20117752 | Generalized epilepsy with febrile seizures plus: novel scn1a mutation. |
| PubMedID- 26291284 | The epileptic syndrome at presentation was epilepsy of infancy with migrating focal seizures (eimfs) in 7 and ohtahara syndrome in 2. |
| PubMedID- 20598821 | Purpose: to describe the eeg pattern of seizures in patients with benign childhood epilepsy with centro-temporal spikes (bcects). |
| PubMedID- 20194124 | Generalized epilepsy with febrile seizures plus (gefs+) is caused by missense mutations in nav1.1 channels, which have variable biophysical effects on sodium channels expressed in non-neuronal cells, but may primarily cause loss of function when expressed in mice. |
| PubMedID- 21826277 | Under certain conditions, and definitely not in the majority of cases, seizures may lead to epilepsy or neurodevelopmental deficits. |
| PubMedID- 23630422 | Although, like other aeds (eg, carbamazepine, lamotrigine), it acts on voltage-gated sodium channels, it is believed to do so by enhancing slow inactivation rather than stabilizing fast inactivation.7 it was included in the systematic review of clinical evidence and original cost-effectiveness analysis of different pharmacological interventions for epilepsy in adults with refractory focal seizures in the 2012 update. |
| PubMedID- 23205932 | Genetic epilepsy with febrile seizures plus (gefs+) phenotypes occurred in 16 relatives. |
| PubMedID- 23531455 | We present findings observed in a patient with atonic seizures due to focal epilepsy, who underwent intracranial video-eeg monitoring and epilepsy surgery, and discuss possible underlying mechanisms. |
| PubMedID- 26236192 | Abbreviations: gefs+, generalized epilepsy with febrile seizures plus; smei, severe myoclonic epilepsy of infancy; fhm1-3, familial hemiplegic migraine type 1-3, respectively; bfns, benign familial neonatal seizures; bfnis, benign familial neonatal-infantile seizures; ee, epileptic encephalopathy; pe, primary erythermalgia; pepd, paroxysmal extreme pain disorder; cip, congenital insensitivity to pain; feps2-3, familial episodic pain syndrome type 2-3, respectively; hsan7, hereditary sensory and autonomic neuropathy type 7; ea1-2, episodic ataxia type 1-2, respectively; sca6-13, spinocerebellar ataxia type 6-13, respectively; pme, progressive myoclonus epilepsy; cdsrr, cone dystrophy with supernormal rod electroretinogram. |
| PubMedID- 22171027 | Neonatal seizures can lead to epilepsy and long-term cognitive deficits into adulthood. |
| PubMedID- 19937810 | The present study was thus designed to validate potential reference genes in a mouse model of mesiotemporal lobe epilepsy (mtle) with focal seizures after unilateral intrahippocampal injection of kainate (ka). |
| PubMedID- 24791094 | Generalized epilepsy with febrile seizures plus syndrome with mutation in various sodium channel genes scn1a, scn1b, scn2a or gaba receptor (gabrg2) genes is being increasingly recognized syndrome in children but semiology is variable and remains not completely understood story. |
| PubMedID- 21109486 | Significance: spike localization may be useful for predicting prognosis in epilepsy with sensorimotor seizures and spikes along with central sulcus. |
| PubMedID- 24578711 | These include diseases of the nervous system (e.g., generalized epilepsy with febrile seizures plus, familial hemiplegic migraine, episodic ataxia, and hyperkalemic and hypokalemic periodic paralysis), the cardiovascular system (e.g., long qt syndrome, short qt syndrome, brugada syndrome, and catecholaminergic polymorphic ventricular tachycardia), the respiratory system (e.g., cystic fibrosis), the endocrine system (e.g., neonatal diabetes mellitus, familial hyperinsulinemic hypoglycemia, thyrotoxic hypokalemic periodic paralysis, and familial hyperaldosteronism), the urinary system (e.g., bartter syndrome, nephrogenic diabetes insipidus, autosomal-dominant polycystic kidney disease, and hypomagnesemia with secondary hypocalcemia), and the immune system (e.g., myasthenia gravis, neuromyelitis optica, isaac syndrome, and anti-nmda n-methyl-d-aspartate receptor encephalitis). |
| PubMedID- 22424762 | We review the effectiveness of the kd in dravet syndrome, epilepsy with myoclonic-atonic seizures, mitochondrial disease, tuberous sclerosis, late infantile and juvenile neuronal ceroid lipofuscinosis, and febrile infection-related epilepsy syndrome. |
| PubMedID- 23684007 | Focality in electro-clinical or neuroimaging data often motivates epileptologists to consider epilepsy surgery in patients with medically-uncontrolled seizures, while not all focal findings are causally associated with the generation of epileptic seizures. |
| PubMedID- 21377902 | Present data demonstrates that epilepsy with frequently recurring seizures may be associated with secondary immune system activation. |
| PubMedID- 21488261 | Disease: generalized epilepsy with febrile seizures plus. |
| PubMedID- 23653348 | Familial cases most commonly arise in genetic epilepsy with febrile seizures plus (gefs+). |
| PubMedID- 22464827 | In only two cases, epilepsy started with myoclonic seizures, and spasms were never observed. |
| PubMedID- 25954161 | As an example, different neural networks may be involved in the generation and maintenance of seizures in patients with temporal lobe epilepsy (bonilha et al., 2012). |
| PubMedID- 21423490 | Likewise, altered eegs are observed commonly in fxs children, and 10–20% display benign focal epilepsy with childhood seizures, typically remitting in late adolescence (musumeci et al., 1999; sabaratnam et al., 2001; berry-kravis, 2002; qiu et al., 2008; hagerman and stafstrom, 2009). |
| PubMedID- 21393095 | During the course of the disease, the patient developed medically refractory epilepsy with partial seizures originating predominantly from the contralateral temporo-occipital area as well as myoclonic and myoclonic-astatic seizures. |
| PubMedID- 20092979 | Ictal single proton emission computed tomography (spect) has demonstrated high levels of sensitivity in localizing seizures among patients with epilepsy of the mesial temporal lobe (mtle). |
| PubMedID- 23998423 | Both experimental and clinical evidence suggests a different inflammatory response to seizures in patients with temporal lobe epilepsy (tle) in comparison to those with extra-tle (xtle). |
| PubMedID- 23773973 | Linkage analysis to seven known loci for fs and/or genetic epilepsy with febrile seizures plus (gefs plus) was performed in a small colombian family. |
| PubMedID- 21750525 | Nonepileptic individuals who are adversely affected by seizures (for example, parents of pediatric patients with epilepsy, and patients with psychogenic nonepileptic seizures) show increased levels of depression, similar to patients with epilepsy. |
| PubMedID- 23823012 | In addition, pyridoxine-dependent seizures, a rare form of early childhood epilepsy, is refractory to usual anti-epileptic medications but can be successfully treated with high doses of pyridoxine. |
| PubMedID- 24151604 | However, the establishment of a reliable and valid animal model of focal neocortical epilepsy with recurrent spontaneous seizures is not trivial 3. |
| PubMedID- 25281316 | This mild impairment of excitability of interneurons leads to a milder disease phenotype in 129/svj mice, similar to genetic epilepsy with febrile seizures plus in humans. |
| PubMedID- 23091322 | After controlling seizures, no patients with absence epilepsy had adhd in our study. |
| PubMedID- 25887401 | His main medical issues are refractory epilepsy with predominantly tonic seizures and recurrent airway infections. |
| PubMedID- 21488258 | Disease: generalized epilepsy with febrile seizures plus. |
| PubMedID- 26236162 | As many as 10%-20% of cases referred to specialized epilepsy units with seemingly intractable seizures do not have epilepsy (6). |