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PedAM

Pediatric Disease Annotations & Medicines




Disease influenza
Symptom |infection
Sentences 1183
PubMedID- 21434564 This case report demonstrates that infection with influenza a virus can present with severe pneumonia and status asthmaticus refractory to medical and ventilatory treatment.
PubMedID- 23468921 Several other clinical studies in adults or children have been reported by investigators in which the addition of various serum or nasal biomarker level measurements to the standard clinical evaluation appeared to add to the diagnostic certainty of respiratory virus infection with seasonal influenza –.
PubMedID- 25598263 According to the analysis of the local autocorrelation and hot spot, northern zhejiang and southern guangdong showed high spatial clusters of human infection with avian influenza a (h7n9) (z>2.58).
PubMedID- 24832117 Factors that trigger human infection with animal influenza virus progressing into a pandemic are poorly understood.
PubMedID- 23653627 For example, amphiregulin produced by ilc2s is required for airway remodeling after infection with the influenza virus (monticelli et al., 2011).
PubMedID- 24655394 Female sex was significantly associated with increased infection risk, while duration of disease and anti-influenza vaccination were protective, the latter even for cutaneous/soft-tissue (mainly herpetic) infections.
PubMedID- 25784441 8 used a knockout mouse model to show mice lacking ifitm3 gene display fulminant viral pneumonia on infection with a low-pathogenicity influenza virus.
PubMedID- 21990967 Because infection with an influenza virus does not always make people ill, the only way to determine the true size and severity of an influenza outbreak is to monitor the occurrence of antibodies (proteins made by the immune system in response to infections) to the influenza virus in the population—so-called serologic surveillance.
PubMedID- 21986509 The yogurt (0.4 ml/day) and eps (20 mug/day) were orally administered to balb/c mice for 21 days prior to intranasal infection with influenza virus a/pr/8/34 (h1n1).
PubMedID- 20031038 On april 24, 2009, international authorities reported cases of infection with a novel influenza a virus (h1n1) strain of swine origin, now known as pandemic (h1n1) 2009 virus; 7 cases in the united states and 3 clusters in mexico were confirmed, and surveillance indicated influenza-like-illness (ili) had been increasing in mexico since march 18, 2009 (1).
PubMedID- 21801627 Although the prevalence of pneumococcal infection in patients with influenza might have been overestimated by more frequent urinary sampling among those with pneumonia, we found that more than one third of the patients had nonpneumonic pneumococcal infections.
PubMedID- 26038443 To assess the potential risk of infection with influenza a h9n2 viruses in mammals, we evaluated the efficiency of viral replication in primary, well-differentiated nhbe cells grown at the air/liquid interface.
PubMedID- 23148654 Some co-morbidities (e.g., immunosuppression, pre-existing pulmonary disease, cardiac disease, diabetes, asthma that requires regular medical attention, smoking, and obesity) have been demonstrated to increase the risk of hospitalization for infection with influenza a/h1n1.
PubMedID- 22399010 Furthermore, fcna-null mice have a greatly increased susceptibility to infection with the influenza a virus.
PubMedID- 21801617 This finding suggests that apart from age (which is likely to reflect past infection with influenza strains that protected against pandemic h1n1 2009) (25), other participant characteristics were not important for determining susceptibility for infection.
PubMedID- 23364956 It has been well established that natural infection with an influenza virus results in protective immunity against reinfection with the same virus strain (strain-specific immunity), drift viruses within the same subtype (subtype-specific immunity) and even with different subtype viruses (heterosubtypic immunity), albeit with less strength than against a homologous strain.45 such commonly observed cross-protection by natural infection serves as a working model of protection afforded by the caivs.
PubMedID- 19592477 The production of regulated on activation, normal t cell expressed and secreted (rantes, a chemokine belong to ccl5) has been found in nasal secretions of patients suffering from upper respiratory tract infection with influenza virus and is implicated in the pathogenesis of airway during influenza virus infection 3.
PubMedID- 22487223 Background: many questions remain concerning the burden, risk factors and impact of bacterial and viral co-infection in patients with pandemic influenza admitted to the intensive care unit (icu).
PubMedID- 21742505 Acute encephalitis, encephalopathy, and seizures are known rare neurologic sequelae of respiratory tract infection with seasonal influenza a and b virus, but the neurological complications of the pandemic 2009 swine influenza a (h1n1) virus, particularly in adults, are ill-defined.
PubMedID- 21994773 Four different strategies were used to delineate the transcriptional response to infection: infection with wild-type influenza virus; infection with a virus lacking ns1, which is impaired in counteracting the antiviral host response; stimulation with ifnβ and transfecting viral rna that triggers the rna-sensing pathway.
PubMedID- 23074666 Goals of the national surveillance system are (1) to monitor and describe the incidence, distribution, and basic epidemiologic characteristics of deaths among children related to infection with influenza, (2) provide data to guide future influenza immunization policy, and (3) recognize influenza seasons in which the impact of influenza is unusually severe among children 5.
PubMedID- 26038770 An h5n1-based matrix protein 2 ectodomain tetrameric peptide vaccine provides cross-protection against lethal infection with h7n9 influenza virus.
PubMedID- 24195173 Two cases of central nervous system manifestation caused by co-infection with influenza type a/h3 and type b.
PubMedID- 23069683 This review focuses on recent understanding of the dynamics of the cytokine response, neutrophil activity, and responsiveness to cytokines and neutrophil lifespan as major elements of lung inflammation resulting in favorable or poor outcomes in lung infection primarily due to pneumococcus and influenza virus.
PubMedID- 21623379 infection with influenza a virus, which activates the nlrp3 inflammasome, resulted in much more production of il-33 by alveolar macrophages, which in turn activated natural helper cells producing substantial il-13.
PubMedID- 23886073 In ferret experiments, infection with various influenza virus a/h1n1 strains or an influenza virus b strain did not produce cross-reactive antibody responses between influenza a and b viruses in hemagglutination inhibition or neutralization assays .
PubMedID- 22815957 To describe such processes at a global level, we recorded gene expression changes in mouse lungs after a non-lethal infection with influenza a virus over a period of 60 days.
PubMedID- 23723976 Evidence that il-18 may act on alternative inflammatory cells is supported by kang et al (15), who showed that il-18r−/− mice were protected from lung damage and inflammation initiated by tobacco smoke plus poly i:c or infection with influenza virus.
PubMedID- 26068081 Sublethal infection of mice with influenza a virus is cleared by day10–14 and no infectious particles can be isolated from the lung of theseanimals there upon48.
PubMedID- 22837197 During infection with influenza a/pr8/34 virus, the absence of either tlr7 or myd88 leads to reduced virus-specific antibodies in the serum and antibody-secreting cells in their secondary lymphoid organs, particularly in bone marrow.
PubMedID- 26236615 Was unique from the fact that legionella co-infection with influenza virus was associated with dic .
PubMedID- 21383977 As ifnar1−/− mice of b6 background exhibited severe pathology in terms of hyper secretion of pro-inflammatory cytokines and neutrophilia in lung after infection with influenza virus, we examined profiles of infiltrated cell populations in balf in a time-dependent manner.
PubMedID- 22210139 The goal of this work was to determine whether the cotton rat sigmodon hispidus, a small laboratory animal susceptible to infection with unadapted influenza viruses, may become such a model.
PubMedID- 22396483 Since human infection with influenza viruses occurs via the respiratory route, infection of laboratory personnel can be prevented by the use of powered air-purifying respirators.
PubMedID- 23734333 Developed a transgenic model of prostate adenocarcinoma expressing a mhc class i-restricted epitope recognized by the 2c clonotypic t-cell receptor (tcr).25 in these mice, the adoptive transfer of cd8+ 2c cells followed by infection with a siy-expressing influenza virus results in the differentiation of transferred lymphocytes into effector cells that rapidly become tolerize upon tumor infiltration.
PubMedID- 23218952 Background: infection with pandemic a/h1n1/2009 influenza virus led to hospitalisation of patients not expected to be at risk of severe disease from seasonal influenza infection.
PubMedID- 25166617 In the context of co-infection with influenza a virus, the pneumococcus was transmitted among wildtype littermates, with approximately half of the contact mice acquiring colonization.
PubMedID- 19888576 N-acetyl-d-neuraminic acid (neu5ac) is a precursor for producing many pharmaceutical drugs such as zanamivir which have been used in clinical trials to treat and prevent the infection with influenza virus, such as the avian influenza virus h5n1 and the current 2009 h1n1.
PubMedID- 19880818 These data demonstrate that infection with influenza results in the reduced expression of transcription factor irf7 in necs from smokers, and that these effects may be mediated by an epigenetic modification of the irf7 gene, thus providing a potential mechanism rendering smokers more susceptible to respiratory virus infections.
PubMedID- 25293394 In response to infection with influenza viruses and bacteria, a complex interplay of cellular signalling mechanisms is initiated, regulating the anti-pathogen response but also pathogen-supportive functions.
PubMedID- 22247048 Animal studies most strongly support a single pathway of coinfection with influenza inoculation occurring approximately 7 days before inoculation with streptococcus pneumoniae, but less-examined pathways of infection also may be important for human disease.
PubMedID- 21429196 In other cases, muscle inflammation may be caused by an allergic reaction, cancer or rheumatoid conditions, or following environmental exposure to xenobiotics or drugs, or infection with viruses (influenza, coxsackie viruses, arboviruses), bacteria (i.e.
PubMedID- 25940072 In 2013, the first human case of infection with avian influenza a (h6n1) virus was reported in taiwan.
PubMedID- 21642589 infection with influenza virus induces il-33 in murine lungs.
PubMedID- 26056568 Following infection with the influenza virus, inflammatory cells of the innate immune system accumulate in the mucosal membrane.
PubMedID- 22269828 Main methods: we assessed survival, weight loss, lung viral load (by rt-pcr), lung injury (by protein content in bronchoalveolar lavage), and inflammation (cell counts, differentials and cytokines in the bronchoalveolar lavage) in balb/c mice after infection with mouse-adapted pandemic influenza strain a/california/04/2009.
PubMedID- 21600019 Notably, human infection with h1n1 swine influenza has been a nationally notifiable disease in united state since 2007 .
PubMedID- 24309113 Upon co-infection with influenza b virus (flub), influenza a virus (flua) replication is substantially impaired.
PubMedID- 24990477 Background: selective prophylactic decontamination of the digestive tract is a strategy for the prevention of secondary nosocomial infection in patients with avian influenza virus subtype h7n9 infection.
PubMedID- 23769236 Human co-infection with novel avian influenza a h7n9 and influenza a h3n2 viruses in jiangsu province, china.

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