Paroxysmal kinesigenic dyskinesia (PKD) is a rare heritable neurologic disorder characterized by attacks of involuntary movement induced by sudden voluntary movements. No previous reports have described cases showing comorbidity with psychiatric disease or symptoms. In Aug 16, 2017, Yasuto Kunii and others published an article in << Neuropsychiatric Disease and Treatment >> which title is “A case of paroxysmal kinesigenic dyskinesia which exhibited the phenotype of anxiety disorder”. In this case, they showed a patient with PKD who exhibited several manifestations of anxiety disorder. This is the first report to describe psychiatric comorbidities or symptoms in a PKD case. The efficacy of psychotropic medication used in this case, the resulting changes in plasma monoamine metabolite levels, and the recent advances in the molecular understanding of PKD suggested slight, but widespread alterations to the neurotransmitter systems in the brain.
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