Intravesical bacillus Calmette Guérin (BCG) instillation has been used as immunotherapy for early stage bladder cancer for >40 years. Complications from this therapy are rare but may result in a spectrum of infectious sequelae. In Jun 17, 2017, Tara Rachakonda and others published an article in << Open Forum Infectious Diseases>> which title is “Pleural Effusion Caused by Bacillus Calmette-Guérin Immunotherapy for Bladder Cancer”, described the case of an elderly man who presented with a pleural effusion and subcutaneous nodule several years after treatment with BCG.
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