Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease that presents with sicca symptoms of the main mucosal surfaces. Patients with pSS have a broad spectrum of laboratory features, such as cytopenias and hypergammaglobulinemia. Although hematological abnormalities are usually seen in pSS patients, agranulocytosis and autoimmune hemolytic anemia (AIHA) are rare. In Dec， 2016, Lin Qiao and others published an article in << International Journal of Rheumatic Disease >> which title is “Agranulocytosis and mixed-type autoimmune hemolytic anemia in primary sjögren's syndrome: a case report and review of the literature”, described a 40-year-old woman with pSS who developed both agranulocytosis and mixed-type AIHA and the patients' blood samples were analyzed.
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