Home Contact Sitemap

eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease whooping cough
Comorbidity C0006017|pertussis
Sentences 16
PubMedID- 21115396 The occasionally severe neurological complications following the human respiratory tract infection 'whooping cough' have been attributed to pertussis toxin (pt) expressed by the causative agent bordetella pertussis.
PubMedID- 24219484 Although there is a high uptake of vaccinations providing protection against bordetella pertussis, the main cause of whooping cough, there has been an increase in the incidence of notifications of the disease in the uk and other developed countries in recent years.
PubMedID- 22794120 The resurgence of pertussis (whooping cough) in australia has attracted community concern, especially with recent deaths in two infants from the australian state of new south wales (nsw) [1,2].
PubMedID- 24312558 Bordetella pertussis, the causative agent of the “whooping cough”, is one such pathogen in which the t3ss is essential for its virulence and persistence in the lower respiratory tract [1], [2].
PubMedID- 25674816 Bordetella pertussis, the causative agent of human whooping cough (pertussis) produces a complex array of virulence factors in order to establish efficient infection in the host.
PubMedID- 23596573 Diphtheria-tetanus-pertussis (whooping cough) (dtp) vaccine in 1955, killed polio vaccine in 1958, and inactivated vaccine for typhoid fever in 1960 were used.
PubMedID- 22940441 Bordetella pertussis, the cause of whooping cough, is highly contagious.
PubMedID- 22863321 B. pertussis, the etiological agent of pertussis (whooping cough) is exclusively adapted to humans; b. parapertussis refers to two groups, one infects only humans and the other infects sheep [2,3]; and b. bronchiseptica establishes both asymptomatic and symptomatic infections in a broad range of mammalian hosts, which sometimes include humans [4-7].
PubMedID- 21524285 In this work we focused on the pathogenic bacterium bordetella pertussis, the causative agent of whooping cough, which remains an important global health problem, with up to 300,000 annual deaths and approximately 45 million cases each year [18,19].
PubMedID- 22608348 Bordetella pertussis, the causative agent of whooping cough, continues to circulate among children and adolescents even in regions with high vaccine coverage.
PubMedID- 21695123 Bordetella pertussis, the causative agent of whooping cough, has been shown to express a variety of virulence-associated factors that in concert enable the bacteria to colonize the mucosa of the upper respiratory tract in humans.
PubMedID- 23027528 Parapertussis in whooping cough cases has been increasing since the introduction of acellular pertussis vaccines containing purified antigens that are common to both strains.
PubMedID- 22479653 Bordetella pertussis, the etiologic agent of whooping cough, was thought to have originated recently from bordetella bronchiseptica that was infecting domestic animals such as pigs and dogs [1]–[3].
PubMedID- 24721229 Infection with b holmesii is frequently misidentified as being with b pertussis, the cause of whooping cough, because routine diagnostic tests for pertussis are not species-specific.
PubMedID- 23012649 Interestingly, these molecules also inhibited the related cam-dependent adenylate cyclase toxin, cyaa, produced by bordetella pertussis the causative agent of whooping cough.
PubMedID- 22852066 Similar to ef, the adenylyl cyclase toxin cyaa secreted by bordetella pertussis, the causative agent of whooping cough, was recently shown to form ccmp, cimp and cump, too [163].

Page: 1