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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease well-differentiated liposarcoma
Comorbidity C0023827|liposarcomas
Sentences 2
PubMedID- 20706648 Dedifferentiated liposarcoma (ddlps) is a term first introduced by evans in 1979 [3] to describe liposarcomas containing a mixture of atypical lipoma/well-differentiated liposarcoma and a high-grade nonlipogenic sarcomatous component, the latter arising either within the same primary tumour (around 90% of cases) or in a recurrence (around 10% of cases).
PubMedID- 21359911 There is considerable variation in the sensitivity of the three main subtypes of liposarcomas, with well-differentiated liposarcomas showing generalised chemo-resistance through to the impressive responses seen anthracyclines and to trabectedin with the myxoid subtype.

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