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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease viral meningitis
Comorbidity C0024266|lymphocytic choriomeningitis
Sentences 1
PubMedID- 22848163 When lymphocytic choriomeningitis viral vectors were injected into mice intravenously, viral particles accumulated in 11% and 60% of splenic dcs on days 3 and 7 after injection.8 lps displaying bacterial flagellin-related peptide could accumulate in about 20% of splenic dcs 1 hour after intravenous injection.14 moreover, α-cd11c f(ab)2-fused ags could accumulate in 1.5% and 81.4% of splenic dcs at 4 and 12 hours after subcutaneous injection.13 these results demonstrated that the α-cd11c-zz-bnc complexes could more promptly and efficiently accumulate in splenic dcs (in 62% of cd11c+ splenocytes at 40 minutes after intravenous injection) than other dc-targeting nanocarriers.

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