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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease vasculitis
Comorbidity C0010403|cryoglobulinemia
Sentences 8
PubMedID- 22956970 All 18 patients had type ii mixed cryoglobulinemia, with symptoms of vasculitis in 13. clinical symptoms of cryoglobulinemia preceded the diagnosis of lymphoma in 7 patients (at a mean time of 3.5 years before lymphoma diagnosis) and were concurrent in the other 6 patients.
PubMedID- 23237994 Rituximab is also an option in essential mixed cryoglobulinemia with uncontrolled vasculitis despite glucocorticoid and/or immunosuppressive treatment.
PubMedID- 21188196 An appropriate approach to treatment of severe acute flares of cryoglobulinemia with glomerulonephritis or vasculitis is combination antiviral therapy using peginterferon and ribavirin for 48 weeks, adding corticosteroids and cyclophosphamide as needed to control severe symptoms.
PubMedID- 20506150 Objective: an uncommon manifestation of hepatitis c virus (hcv) infection is systemic vasculitis associated with type ii cryoglobulinemia (cryoglobulinemic vasculitis), a proliferative b cell disorder that transforms into b cell malignancy in 5-10% of patients.
PubMedID- 22087127 However, ifn-α may induce vasculitis with or without cryoglobulinemia, and can increase preexisting ischemia, leading to purpura, skin ulcerations, arthritis or ischemic polyneuropathy [24][25].
PubMedID- 21049729 In this report, the clinical course of a patient with established psoriasis who received rituximab therapy for vasculitis associated with mixed cryoglobulinemia (mc) type ii is described.
PubMedID- 20952479 Objective: to describe hepatitis c virus (hcv)-related systemic vasculitis in patients without detectable mixed cryoglobulinemia (mc) and to compare them to typical cases of hcv-mc vasculitis.
PubMedID- 25659437 In another report, reactivation of cerebral toxoplasmosis after rtx therapy in a 71-year-old female with cutaneous vasculitis associated with type i cryoglobulinemia was described [14].

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