eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | tuberous sclerosis |
| Comorbidity | C0018552|hamartomas |
| Sentences | 4 |
| PubMedID- 25390511 | We present three unique cases of multifocal and bilateral retinal astrocytic hamartomas in patients with suspected tuberous sclerosis complex. |
| PubMedID- 22654497 | It has been shown that hamartomas associated with tuberous sclerosis complex involving organs other than the eyes (kidney, brain, and skin) are highly angiogenic and may express vegf.3,8,9 as far as we know, there are no reports regarding vegf expression in the tumor of aggressive retinal astrocytoma, although the vitreous vegf concentration has been reported to be high in aggressive retinal astrocytoma (table 1).3 in the present study, we showed vegf expression in both retinal tumor and epiretinal membrane. |
| PubMedID- 26057258 | Conclusion: retinal astrocytic hamartomas in association with tuberous sclerosis complex is considered to be a relatively stationary lesion that has little potential for aggressive behavior. |
| PubMedID- 26550497 | Medical history was significant for tuberous sclerosis with retinal hamartomas, renal mass, mental retardation, complex partial epilepsy, quadriparesis, severe kyphoscoliosis, iron deficiency anemia, reflux esophagitis with esophageal ulcers, chronic gastritis, and multiple pulmonary nodules. |
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