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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease tremor
Comorbidity C0011570|depression
Sentences 3
PubMedID- 26167103 At the same dose, mice showed respiratory depression after administration of 14 and revealed tremors after administration of 22. only one compound 24 revealed neurotoxicity at a dose of 100 mg/kg.
PubMedID- 24086664 It is noteworthy that this distributed neural pathway is engaged in clinical phenomena that involve both emotions and sensorimotor processes, such as essential tremor associated with anxiety and depression disorders [28], stuttering [29,30], impulsivity [31] and even hysteria [32-35].
PubMedID- 25744879 Rearing, grooming, jumping, genital licking, leg licking, head shakes with associated depression (increased immobility in forced swim test) as well as anxiety (decreased the number of entries and time spent in open arm in elevated plus maze) in nicotine dependent animals.

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