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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease thrombophilia
Comorbidity C0040053|thrombosis
Sentences 38
PubMedID- 26102090 We present a case of a successful living-related renal transplant in man with a recent history of repeat episodes of vascular access thrombosis attributed to inherited thrombophilia (heterozygosity for factor v mutation q506 and homozygosity for mutation t677 for methylene-tetrahydrofolate reductase).
PubMedID- 20962562 We postulated that ivc thrombosis occurred due to hypercoagulable status of uc and intra-abdominal inflammation caused by mesalazine-induced pancreatitis.
PubMedID- 20979943 Aims: to review our single-center experience of preemptive anticoagulation for the prevention of allograft thrombosis in patients with hypercoagulable states.
PubMedID- 20358016 Some reports have suggested significant side effects with the procedure, such as arterial thrombosis, due to the hypercoagulable state of pregnancy, which may increase vascular complications (10).
PubMedID- 21847433 The risk of thrombosis attributable to a thrombophilia during free flap surgery is not known, and the relative risk ratios for thrombophiliacs versus normal cohorts have not been reported.
PubMedID- 23569516 This can be attributed to the short half-lives of these two proteins – 1.5 to 6 hours for factor vii and 8 hours for protein c. the resultant hypercoagulable state leads to thrombosis and blood clots the in the dermal capillaries which causes skin necrosis due to interruption in the blood supply to skin.
PubMedID- 24416352 [2], [3], [4] the predisposing thrombophilic factors, particularly thrombosis due to the hypercoagulable state, or thrombophlebitis resulted from long-term oral contraceptives, cause the secondary onset of thrombus in hv and obstruction of hv.
PubMedID- 26161329 The final diagnosis was cerebral venous sinus thrombosis probably due to hypercoagulable state in pregnancy.
PubMedID- 22688554 Inflammation in sepsis is associated with hypercoagulation that may lead to thrombosis and disseminated intravascular coagulation.
PubMedID- 24672719 hypercoagulable disorders can lead to deep vein thrombosis (dvt), arterial thrombosis or embolization, and early or recurrent bypass graft failure [1, 2].
PubMedID- 20939207 Atypical presentation of basilar artery thrombosis due to hypercoagulable state and incidental patent foramen ovale: a case report.
PubMedID- 25875603 Antiphospholipid syndrome (aps) is a hypercoagulable state that leads to thrombosis and recurrent pregnancy loss related to the presence of antiphospholipid antibodies (lac, anticardiolipin, antia2-glycoprotein).
PubMedID- 20082713 Hence, in the context of hiv infection, we suspected a hypercoagulable state with micro-thrombosis in the distal portal veins causing nrh.
PubMedID- 25015068 The perioperative period is a unique state of generalized hypercoagulability which can predispose people to des thrombosis when combined with the rebound hypercoagulable effect of antiplatelet withdrawal.
PubMedID- 20083915 Candidates for anticoagulation are women with a current thrombosis, a history of thrombosis, thrombophilia, and a history of poor pregnancy outcome, or risk factors for postpartum thrombosis.
PubMedID- 23518853 Our findings suggest that rfa is an effective microinvasive technique, which can result in a hypercoagulable state, with venous thrombosis and stenosis.
PubMedID- 24700919 The most common underlying mechanisms implicated in ami during pregnancy are atherosclerotic coronary artery disease (cad), coronary thrombosis with hypercoagulability and coronary artery dissection.
PubMedID- 21445949 We present a pediatric patient treated with high dose intravenous immunoglobulin (ivig) for acute immune thrombocytopenic purpura (itp), who developed cerebral sinus thrombosis in the absence of any identifiable hypercoagulable state.
PubMedID- 23768451 Introduction: congenital antithrombin (at) deficiency is an inherited thrombophilia with high thrombosis prevalence.
PubMedID- 24613695 Background: hereditary thrombophilias may associate with uteroplacental thrombosis leading to adverse pregnancy outcomes.
PubMedID- 24772710 Embolism from mitral valve prosthesis, in-situ thrombosis due to hypercoagulable state of pregnancy or coronary spasm could be responsible.
PubMedID- 25228558 Oral contraceptive pills, often prescribed to adolescent females for various indications, such as tobacco use, obesity and hypertension may trigger symptomatic thrombosis, especially in carriers of genetic thrombophilia traits.
PubMedID- 23946906 We considered reversal of heparin anticoagulation with protamine sulfate; however, we were concerned about the potential risk of rebound hypercoagulability leading to valvular thrombosis, heart failure, thromboembolism, and even maternal mortality.6 the options for management of valve thrombosis include clot lysis with thrombolytic agents or emergency valvular surgery.7 however, in the setting of intracranial hemorrhage, thrombolytic therapy is absolutely contraindicated and the surgical option would have required intravenous ufh infusion during and following surgery that could be fatal in a setting of intracranial bleeding.
PubMedID- 24254895 The purpose of this study was to characterize differences in the prevalence of hereditary and acquired thrombophilia in patients with splanchnic vein thrombosis (svt).
PubMedID- 22140507 The ebv virus was also found to have caused venous thrombosis in a patient with hereditary thrombophilia [24].
PubMedID- 25013680 The major causes of non-cirrhotic portal hypertension include hypercoagulable states leading to spontaneous thrombosis, radiation, severe pancreatitis and intra-abdominal tumors [15].
PubMedID- 23247829 Background: the utility of thrombophilia testing in patients with splanchnic vein thrombosis (spvt) has not previously been rigorously evaluated.
PubMedID- 23840992 Malignancy is known to be one of the predisposing factors of cerebral venous thrombosis (cvt) due to its hypercoagulable state.
PubMedID- 25709842 We [2] and then others [3] have postulated a sequence for development of on: venous thrombosis due to thrombophilia-hypofibrinolysis [4] causes osseous venous outflow obstruction, leading to increased intraosseous venous pressure, reduced arterial flow, ischemia, and bone death.
PubMedID- 22188175 Conclusions: simple signal processing of the aptt and the use of dynamic parameters represents a stronger predictive marker for hypercoagulation in patients with verified venous thrombosis than the standard aptt measurement.
PubMedID- 26064514 The final diagnosis was aki secondary to bilateral renal artery thrombosis probably due to hypercoagulability of acute necrotizing pancreatitis.
PubMedID- 21220364 Several small studies have reported an elevated risk of venous thrombosis (vt) with thrombophilia and oral contraceptive (ocp) use.
PubMedID- 21105319 hypercoagulability with thrombosis further impairs blood flow, while oxidative stress damages endothelial cells and compromises vascular patency.
PubMedID- 21389667 Uc has been reported to show hypercoagulation status, leading to deep vein thrombosis within the body which sometimes causes pulmonary infarction, but occurrence of cerebral sinus thrombosis is rare.
PubMedID- 22927730 The prognosis and pathophysiology of optic neuropathy in autoimmune diseases like lupus is different than ms.49–54 small vessel vasculitis and thrombosis associated with hypercoagulability may cause ischemic optic neuropathy.
PubMedID- 24501870 This case shows the need of large prospective studies that should be undertaken to refine the risks and establish the associations of thrombophilias with venous thrombosis among contraceptive users.
PubMedID- 24441348 Thyrotoxic hypercoagulable state with cerebral venous thrombosis and venous infarction masquerading as epilepsia partialis continua.
PubMedID- 24693443 A significant added risk to thrombosis is the presence of coexistent inherited thrombophilia during pregnancy [19].

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