eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | thrombophilia |
| Comorbidity | C0040034|thrombocytopenia |
| Sentences | 3 |
| PubMedID- 21081779 | Heparin-induced thrombocytopenia is an example of an acquired hypercoagulable state that has been well studied and, when recognized, responds to appropriate therapy. |
| PubMedID- 20478689 | Compensated hypercoagulability states associated with a thrombocytopenia (plt<150k/mm(3)) affect 25 to 50% of severe pe patients. |
| PubMedID- 21415977 | Sepsis is almost invariably associated with haemostatic abnormalities ranging from isolated thrombocytopenia and/or subclinical activation of blood coagulation (hypercoagulability), to sustained systemic clotting activation with massive thrombin and fibrin formation and subsequent consumption of platelets and proteins of the haemostatic system (acute disseminated intravascular coagulation, dic).1 from a clinical standpoint, isolated thrombocytopenia, which is seen mainly in viral infections, is only occasionally serious enough to cause a bleeding diathesis. |
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