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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease thrombophilia
Comorbidity C0021053|immune disorder
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PubMedID- 22121422 Antiphospholipid syndrome (aps) is an autoimmune disorder of acquired hypercoagulability characterized by the association of vascular thromboses (venous, arterial, small vessels) and or pregnancy morbidity (foetal loss, premature birth or recurrent embryonic losses) and persistent elevated serum levels of antiphospholipid antibodies (anticardiolipin, lupus anticoagulant or anti- b2glycoprotein i) [1] it is also considered as a multisystemic disorder with a wide spectrum of presentations cutting across all subspecialties of medicine.

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