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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease thrombophilia
Comorbidity C0018801|heart failure
Sentences 3
PubMedID- 22934233 Given the absence of other risk factors, it was our firm believe that our patient's uedvt was due to a hypercoagulable state associated with congestive heart failure (chf) and hiv infection.
PubMedID- 20947383 Pharmacokinetics and pharmacodynamics of rivaroxaban and its effect on biomarkers of hypercoagulability in patients with chronic heart failure.
PubMedID- 23946906 We considered reversal of heparin anticoagulation with protamine sulfate; however, we were concerned about the potential risk of rebound hypercoagulability leading to valvular thrombosis, heart failure, thromboembolism, and even maternal mortality.6 the options for management of valve thrombosis include clot lysis with thrombolytic agents or emergency valvular surgery.7 however, in the setting of intracranial hemorrhage, thrombolytic therapy is absolutely contraindicated and the surgical option would have required intravenous ufh infusion during and following surgery that could be fatal in a setting of intracranial bleeding.

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