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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease thrombocytopenia
Comorbidity C0155765|microangiopathy
Sentences 6
PubMedID- 25852897 thrombocytopenia with or without microangiopathy following quinine is often referred to as quinine ‘hypersensitivity’.
PubMedID- 23607458 Typical haemolytic uraemic syndrome (hus) is caused by shiga toxin (stx)-producing escherichia coli infections and is characterized by thrombotic microangiopathy that leads to haemolytic anaemia, thrombocytopenia and acute renal failure.
PubMedID- 22507807 Except in the occasional situations in which thrombocytopenia is associated with thrombotic microangiopathy, such as catastrophic aps, bleeding is uncommon in aps patients.
PubMedID- 20350374 Hus is a thrombotic microangiopathy and consists of nonimmune hemolytic anemia, thrombocytopenia, and renal failure (1).
PubMedID- 22309967 In adults, the difficulty of differentiating ttp, which is much more common than hus and the need for a speedy diagnosis to provide life-saving plasma therapy has resulted in the term ttp/hus for adult forms of thrombotic microangiopathy that present with unexplained thrombocytopenia and microangiopathic hemolytic anemia without a dic.
PubMedID- 22851928 Typical hus is a thrombotic microangiopathy with hemolytic anemia, thrombocytopenia and acute renal failure that is epidemic, diarrhea related and caused by verotoxin (shiga toxin)-producing escherichia coli (o157:h7, o104:h4).

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