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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease thrombocytopenia
Comorbidity C0040053|thrombus
Sentences 3
PubMedID- 23056879 Maeda et al found a subpopulation of ph patients with increased propensity to thrombosis as suggested by increased platelet protease-activated receptor 1 (par1, a key element in the activation of human platelets by thrombin) expression and par-mediated surface exposure of p-selectin (an adhesion molecule, a marker for in vivo platelet activation, and an essential component in thrombus formation), associated with thrombocytopenia [6].
PubMedID- 25250305 Thrombotic microangiopathies (tma) are rare but severe disorders, characterized by endothelial cell activation and thrombus formation leading to hemolytic anemia, thrombocytopenia, and organ failure.
PubMedID- 21242799 The adrenal gland has a vascular construction that lends itself to venous thrombus in the setting of heparin-induced thrombocytopenia and subsequent arterial hemorrhage.

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