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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease thrombocytopenia
Comorbidity C0035078|renal failure
Sentences 2
PubMedID- 21694933 Hemolytic uremic syndrome (hus) is a thrombotic microangiopathy characterized by hemolytic anemia and thrombocytopenia often complicated by acute renal failure in children.1 both typical or diarrhea-associated hus form is associated with infection by escherichia coli and has a good prognosis.2 a second less common from, termed atypical, nondiarrhea-associated hus (ahus) is a heterogeneous recurrent disorder which displays high mortality and morbidity.3 this form can occur at any age with familial and sporadic cases.
PubMedID- 20392606 Recent studies have reported that the incidence of linezolid-induced thrombocytopenia was higher in patients with renal failure than in patients with normal renal function, although the underlying mechanisms of this toxicity are still unknown.

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