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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease thrombocytopenia
Comorbidity C0030312|bone marrow failure
Sentences 3
PubMedID- 20823093 Anaemia, leucopenias and thrombocytopenia may result from bone marrow failure or excessive peripheral cell destruction, both of which may be immune mediated.
PubMedID- 24778999 Organ infiltration by mc may lead not only to organomegaly, but also to impairment or even loss of organ function and in severe (high grade) disease, bone marrow failure with anemia, thrombocytopenia, and/or recurrent infections (due to neutropenia) may occur.
PubMedID- 23690288 Pathophysiology and management of thrombocytopenia in bone marrow failure: possible clinical applications of tpo receptor agonists in aplastic anemia and myelodysplastic syndromes.

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