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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease thrombocytopenia
Comorbidity C0002878|hemolytic anemia
Sentences 25
PubMedID- 20436664 Thrombotic microangiopathies (tma) represent a rare and heterogeneous group of diseases defined by microangiopathic hemolytic anemia with peripheral thrombocytopenia and organ failure of variable severity.
PubMedID- 21776377 A 15-year-old female was admitted to our hospital because of thrombocytopenia with hemolytic anemia.
PubMedID- 21295897 We report the first case to our knowledge of a patient who developed an acute decrease in kidney function, nonimmune microangiopathic hemolytic anemia with schistocytes, and thrombocytopenia after 4 intravitreal injections of ranibizumab.
PubMedID- 21151638 [8] reported a case of thrombocytopenia associated with hemolytic anemia in a patient with intracardiac metastasis originating from a testicular teratoma.
PubMedID- 23827373 Hemolytic and uremic syndrome (hus) is a classical form of thrombotic microangiopathies characterized by the association of hemolytic anemia with schizocytes, thrombocytopenia, and acute renal failure.
PubMedID- 20056203 Result(s): both patients developed a very rare complication after surgery of severe thrombocytopenia with microangiopathic hemolytic anemia leading to acute renal failure.
PubMedID- 25821808 Eryptosis is triggered by hemolytic uremic syndrome (hus), characterized by hemolytic anemia with fragmented erythrocytes, thrombocytopenia, and acute renal failure [198].
PubMedID- 20359326 This disease causes hemolytic anemia with fragmentation of erythrocytes, thrombocytopenia, diffuse and nonfocal neurologic findings, and decreased renal function.
PubMedID- 23304632 The traditional diagnostic criteria for this syndrome include hemolytic anemia with fragmented erythrocytes, thrombocytopenia, and renal failure [1].
PubMedID- 21151550 Peripheral blood smear examination revealed schistocytes and thrombocytopenia consistent with microangiopathic hemolytic anemia (fig.
PubMedID- 20331741 Recognition of cancer-associated microangiopathic hemolytic anemia with thrombocytopenia (ca-mha) is paramount to avoid inappropriate pe therapy and delays in cancer-specific chemotherapy.
PubMedID- 21559455 The criteria for hus diagnosis were microangiopathic hemolytic anemia with schizocytes, thrombocytopenia (platelet count <150×109/l) and acute renal failure (serum creatinine level higher than the normal values considering the age of the patient).
PubMedID- 21772952 Evans syndrome (es) is an autoimmune disorder characterized by thrombocytopenia and/or neutropenia associated with hemolytic anemia (aha).1–3 it is a potentially life-threatening condition that may be associated with other underlying autoimmune or lymph-proliferative disorders.4 standard treatment consists of transfusions, corticosteroids and immunoglobulins (ivig); second-line treatment in es evolved over the last decade, and includes at present anti-cd20 rituximab, vincristine, alkalizing agents, mycophenolate mofetil (mmf) or cyclosporine (cya).5–6,8–14 long-term remissions induced by splenectomy are less frequent than in uncomplicated immune thrombocytopenia purpura (itp).
PubMedID- 21961487 He was diagnosed to have es at the age of 8, during another bout of thrombocytopenia, this time associated with coombs-positive hemolytic anemia.
PubMedID- 23961497 The overall impression on hematological examination was hemolytic anemia with thrombocytopenia and reactive marrow hyperplasia.
PubMedID- 23602056 thrombocytopenia together with microangiopathic hemolytic anemia is mandatory for the diagnosis of ttp and if these two criteria met in a patient, tpe should be performed immediately.
PubMedID- 22374533 It is important to suspect ttp when hemolytic anemia with thrombocytopenia is observed, and to check the activity and antigen of adamts13 immediately for the diagnosis.
PubMedID- 20636987 Objective: to identify and characterize the syndrome of immune-mediated hemolytic anemia (imha) with concurrent severe thrombocytopenia (
PubMedID- 20399168 hemolytic anemia with schistocytes, thrombocytopenia without evidence of disseminated intravascular coagulation, and renal failure are consistently found.
PubMedID- 23842487 Background: hemolytic anemia with thrombocytopenia and schistocytosis is suggestive of thrombotic thrombocytopenic purpura (ttp).
PubMedID- 22929300 59. thrombocytopenia associated with mechanical hemolytic anemia should suggest tma, even in the absence of organ failure (strong agreement).
PubMedID- 23943710 A congenital or acquired deficiency of adamts-13 can result in accumulation of the ultralarge vwf multimers leading to microangiopathic thromboses and severe thrombocytopenia with resultant hemolytic anemia and thrombotic sequelae.6 in the rare familial forms of ttp, mutations of the adamts-13 gene can be found resulting in significant risk of ttp in pregnancy in affected women.6 acquired ttp is postulated to be secondary to viral infections that trigger production of antibodies targeted against adamts-13.7 women with acquired ttp also have a high risk of recurrence in a subsequent pregnancy.6 it has been proposed that specific proteins found in the placental circulation serve as antigens that trigger maternal antibody production against adamts-13.
PubMedID- 24013519 A mixed-type autoimmune hemolytic anemia with immune thrombocytopenia related with myositis and post-transplantation lymphoproliferative disorder.
PubMedID- 23989401 For thrombotic thrombocytopenic purpura and hemolytic uremic syndrome (ttp-hus) the diagnosis of coombs negative hemolytic anemia together with thrombocytopenia should lead to the detection of fragmentocytes in peripheral blood smears.
PubMedID- 24490094 There are many reported cases of hemolytic anemia with or without thrombocytopenia in gastric cancer.

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