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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease tetralogy of fallot
Comorbidity C0020305|hydrops fetalis
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PubMedID- 25032061 Premature constriction of the distal ductus arteriosus as a result of maternal nonsteroidal anti-inflammatory drug exposure or congenital heart defects such as truncus arteriosus or tetralogy of fallot have been associated with hydrops fetalis.22 large thoracic space occupying lesions such as congenital cystic adenomatoid malformations, bronchopulmonary sequestrations, bronchogenic cysts, congenital lobar emphysema, and segmental bronchial atresia may also result in hydrops from direct cardiac compression.23 less common intrathoracic tumors that have also been reported to cause hydrops fetalis include mediastinal teratomas, fibrosarcomas, lymphangiomas, and intrapericardial teratomas.242526272829 in our case, we propose that multiple ganglioneuromas compressed the distal ductal and aortic arches as well as the proximal descending aorta, eventually leading to the development of nih fetalis.

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