eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | synovitis |
| Comorbidity | C0022116|ischemia |
| Sentences | 1 |
| PubMedID- 26069547 | Although the exact mechanisms by which pain in osteoarthritis is generated remains unknown—nociceptive fibers are found only in the subchondral bone and joint capsule but not in cartilage—it is believed that intraarticular factors released from bone or synovium cause hypersensitivity of related structures such as the periosteum, subchondral bone, or marrow bone.4 concomitant intraarticular hypertension and ischemia due to synovitis could be other sources of joint pain. |
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