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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease splenic marginal zone lymphoma
Comorbidity C0024299|lymphoma
Sentences 8
PubMedID- 25925423 Some authors have hypothesized that hms could be considered as a pre-malignant state that could evolve to chronic lymphocytic or hairy cell leukaemia or splenic lymphoma with villous lymphocytes, as a result of a multi-step process with a single clone selection in a set of deregulated polyclonal expansion of lymphocytes [21-23].
PubMedID- 24171046 However, in our patient, there was no evidence of splenomegaly and circulating villous lymphocytes, which is the characteristic of splenic lymphoma with villous lymphocytes.
PubMedID- 24764738 Further diagnostic and staging workup including bone marrow biopsy, touch, and imaging revealed stage iv splenic lymphoma with villous lymphocytes.
PubMedID- 22956970 The authors concluded that splenic lymphoma with villous lymphocytes could be integrated in the spectrum of cryoglobulin-associated b-cell proliferations, configuring a new clinical entity.
PubMedID- 24416499 There are case reports of b-cell chronic lymphocytic leukemia, splenic lymphoma with villous lymphocytes, hairy cell leukemia, monocloncal gammopathy of undetermined significance (mgus), and multiple myeloma associated with lgl leukemia.13-15 in a french cohort, myelodysplasia and b-cell lymphoid neoplasms were diagnosed in 17% and 5% of patients, respectively.
PubMedID- 22712014 splenic lymphoma with villous lymphocytes with central nervous system involvement and bone marrow invasion by malignant lymphoma cells (b cell, cd20+) was diagnosed based on whole-body ct, brain mri, lumbar puncture, and bone marrow aspiration.
PubMedID- 23543122 On bone marrow examination, differential diagnosis was given as splenic lymphoma with villous lymphocytes (slvl) and prolymphocytic variant of hairy cell leukemia.
PubMedID- 24290221 Materials and methods: our studies were conducted in mcl cell lines jeko-1 and mino, as well as primary b-cell lymphoma samples of mcl and splenic marginal zone lymphoma (smzl), where we treated cells with sgi-1776 and bendamustine.

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