eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | small cell carcinoma |
| Comorbidity | C0220650|brain metastasis |
| Sentences | 22 |
| PubMedID- 26014133 | Background: non-small cell lung cancer (nsclc) with brain metastasis (bm) harboring an epidermal growth factor receptor (egfr) mutation shows good response to tyrosine kinase inhibitors (tkis). |
| PubMedID- 22580972 | Five-year tumor-free survival after aggressive trimodality therapy for t3n0m1b non-small cell lung cancer with synchronous solitary brain metastasis. |
| PubMedID- 25510753 | Efficacy of surgical treatment for brain metastasis in patients with non-small cell lung cancer. |
| PubMedID- 21626441 | Primary esophageal small cell carcinoma with brain metastasis and with cd56, kit, and pdgfra expressions. |
| PubMedID- 23467694 | Objective: to assess prognostic factors and validate the effectiveness of recursive partitioning analysis (rpa) classes and graded prognostic assessment (gpa) in 290 non-small cell lung cancer (nsclc) patients with brain metastasis (bm). |
| PubMedID- 25993304 | Herein, we present evidence that elevated levels of visfatin in the serum of sclc patients were associated with brain metastasis, and visfain was increased in nci-h446 cells, a sclc cell line, during interacting with human brain microvascular endothelial cells (hbmec). |
| PubMedID- 24023324 | Conclusion: the number of involved extracranial organs is an independent prognostic factor of survival in sclc patients with brain metastasis. |
| PubMedID- 26498354 | Greater efficacy of chemotherapy plus bevacizumab compared to chemo- and targeted therapy alone on non-small cell lung cancer patients with brain metastasis. |
| PubMedID- 24077347 | Associations between single-nucleotide polymorphisms in the pi3k-pten-akt-mtor pathway and increased risk of brain metastasis in patients with non-small cell lung cancer. |
| PubMedID- 24864257 | Clinical studies using fotemustine have been conducted in malignant glioma, brain metastasis of non-small cell lung cancer, and disseminated malignant melanoma. |
| PubMedID- 24628530 | Findings: many single center studies showed low incidence of brain metastasis in patients with esophageal small cell carcinoma (scc). |
| PubMedID- 25579245 | Background: the appropriate treatment of non-small cell lung cancer (nsclc) with single brain metastasis (sbm) is still controversial. |
| PubMedID- 24345489 | Methods: the clinical data of 46 non-small cell lung cancer patients with synchronous solitary brain metastasis were retrospectively reviewed. |
| PubMedID- 25749580 | Fighting cancer on all fronts: stereotactic radiosurgery and the role for aggressive primary treatment in non-small cell lung cancer patients with one brain metastasis. |
| PubMedID- 24495594 | Definitive chemoradiation therapy following surgical resection or radiosurgery plus whole-brain radiation therapy in non-small cell lung cancer patients with synchronous solitary brain metastasis: a curative approach. |
| PubMedID- 19592127 | Background: the optimal treatment for non-small cell lung cancer (nsclc) patients with asymptomatic brain metastasis is still controversial. |
| PubMedID- 26467930 | This study showed that pci reduces the incidence of brain metastasis in patients with ed-sclc who achieve stable disease or a better response with initial therapy, but it does not prolong survival [5••]. |
| PubMedID- 25735792 | Activity of pemetrexed-based regimen as first-line chemotherapy for advanced non-small cell lung cancer with asymptomatic inoperable brain metastasis: a retrospective study. |
| PubMedID- 22984665 | The histological distribution was as follows: two falx meningioma, six glioblastoma multiform (gbm), two anaplastic oligodendroglioma, one low grade oligodendroglioma, and one small cell lung cancer with brain metastasis. |
| PubMedID- 20169130 | Aggressive treatment, including resection of both metastasis and primary tumor, has been studied for non-small cell lung cancer patients with synchronous solitary brain metastasis. |
| PubMedID- 20224732 | The present case suggests that there are small cell carcinomas with a solitary brain metastasis without a radiologically detected primary site. |
| PubMedID- 25239373 | We conducted a retrospective study to evaluate risk factors for brain metastasis (bm) in patients with surgically resected sclc to identify those most likely to benefit from pci. |
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