eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | small cell carcinoma |
| Comorbidity | C0085110|severe combined immunodefic |
| Sentences | 2 |
| PubMedID- 21625386 | Furthermore, a recent study has shown a therapeutic effect of anti-pthrp treatment with zoledronic acid (a third-generation bisphosphonate) for bone metastases of small cell lung cancer in severe combined immunodeficient mice [35]. |
| PubMedID- 21551260 | Intravenous inoculation into natural killer cell-depleted severe combined immunodeficient mice of the small cell lung cancer cell lines h1048 (producing low amounts of vegf) and sbc-5 (producing intermediate amounts of vegf) resulted in hematogenous metastases into multiple organs, including the liver, lungs, kidneys, and bones, whereas intravenous inoculation of pc14pe6, a non-small cell lung cancer cell line producing high amounts of vegf, resulted in lung metastases followed by massive pleural effusion. |
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