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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease sickle cell anemia
Comorbidity C1260402|splenic sequestration
Sentences 3
PubMedID- 23657515 Context: homozygous (ss) sickle-cell anemia complicated by acute splenic sequestration in adults is a rare event, and it has never been reported during pregnancy.
PubMedID- 26344060 There is a need for a well-designed, adequately-powered, randomized controlled trial to assess the benefits and risks of splenectomy compared to transfusion programmes, as a means of improving survival and decreasing mortality from acute splenic sequestration in people with sickle cell disease.there are no trials included in the review and we have not identified any relevant trials up to june 2015.
PubMedID- 23728644 There is a need for a well-designed, adequately-powered, randomized controlled trial to assess the benefits and risks of splenectomy compared to transfusion programmes, as a means of improving survival and decreasing mortality from acute splenic sequestration in people with sickle cell disease.

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