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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease sickle cell anemia
Comorbidity C0020542|pulmonary hypertension
Sentences 22
PubMedID- 22536523 The observations by this study tend to suggest that these parameters could be useful for early detection and prevention of pulmonary hypertension in patients with sickle cell anaemia.
PubMedID- 21510733 pulmonary hypertension in children with sickle cell disease.
PubMedID- 22829869 As such, upregulation of arginase activity and expression has been reported to play a role in various vascular pathologies, such as pulmonary hypertension associated with sickle cell disease [1], primary pulmonary arterial hypertension, [2] ischemia-reperfusion, [3] uremia, [4] as well as various animal models of arterial hypertension, [5] aging, [6] sexual arousal, [7], [8] diabetes [9] and atherosclerosis [10], [11], [12].
PubMedID- 22030000 pulmonary hypertension in sickle cell disease.
PubMedID- 22029997 pulmonary hypertension in sickle cell disease.
PubMedID- 25710019 Qtc dispersion, the difference between maximal and minimal qt interval duration in the 12 standard ecg leads, was also significantly increased in sickle cell disease, especially in patients with pulmonary hypertension, correlated with regional inhomogeneity of ventricular repolarization [104].
PubMedID- 21732836 A hemodynamic study of pulmonary hypertension in sickle cell disease.
PubMedID- 24515990 Hypoxic response contributes to altered gene expression and precapillary pulmonary hypertension in patients with sickle cell disease.
PubMedID- 20553267 pulmonary hypertension in sickle cell disease children under 10 years of age.
PubMedID- 22210808 pulmonary hypertension in patients with sickle cell disease: not so frequent but so different.
PubMedID- 24942020 Elevated tricuspid regurgitant velocity as a marker for pulmonary hypertension in children with sickle cell disease: less prevalent and predictive than previously thought.
PubMedID- 22029998 pulmonary hypertension in sickle cell disease.
PubMedID- 22029996 pulmonary hypertension in sickle cell disease.
PubMedID- 26370739 Pulmonary endarterectomy as treatment for chronic thromboembolic pulmonary hypertension in sickle cell disease.
PubMedID- 22029999 pulmonary hypertension in sickle cell disease.
PubMedID- 24791052 Prevalence of pulmonary hypertension in sickle cell anaemia patients of a tertiary hospital in nigeria.
PubMedID- 26176970 pulmonary hypertension in sickle cell disease.
PubMedID- 25398989 Vasculopathy and pulmonary hypertension in sickle cell disease.
PubMedID- 23271856 Previous studies have reported abnormal pulmonary function and pulmonary hypertension among nigerians with sickle cell disease, but there is no report of interstitial lung disease among them.
PubMedID- 21873028 Abnormalities in cardiac structure and function in adults with sickle cell disease are not associated with pulmonary hypertension.
PubMedID- 26270484 This study aimed to evaluate the characteristics and severity of pulmonary hypertension in patients with sickle cell disease using detailed echocardiography.
PubMedID- 19488751 Significant, independent associations were found with both elevated ldh concentration and degree of anemia, suggesting that hemolytic and other mechanisms contribute to pulmonary hypertension in patients with sickle cell disease.

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