eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | sickle cell anemia |
| Comorbidity | C0018799|heart disease |
| Sentences | 3 |
| PubMedID- 25600143 | Although cardiovascular mortality has declined by ≈30% in the past decade, the incidence of sudden cardiac death (scd) remains high.1 an estimated 80% of scds are associated with coronary heart disease (chd),2 but despite significant advances in the management of cardiovascular risk factors, approximately half of all scds may be the first clinical manifestation of chd. |
| PubMedID- 25867016 | The techniques described herein are important for researchers and clinicians seeking to elucidate comorbid thrombotic pathologies such as myocardial infarctions, ischemic heart disease, and strokes in patients with diabetes or sickle cell disease. |
| PubMedID- 24455402 | Although more than 80% of scds occur in patients with coronary heart disease or congestive heart failure, conditions strongly linked to adiposity [3–5], several traditional adiposity-related risk factors such as high cholesterol or high blood pressure are not strongly predictive of scd. |
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